Yufeng Shen

Research interests

Publications

• Tissue Determinants of Human NK Cell Development, Function, and Residence

  Cell · 2020 · https://doi.org/10.1016/j.cell.2020.01.022

• Large-scale targeted sequencing identifies risk genes for neurodevelopmental disorders

  Nature Communications · 2020 · https://doi.org/10.1038/s41467-020-18723-y

• Nanodroplet processing platform for deep and quantitative proteome profiling of 10–100 mammalian cells

  Nature Communications · 2018 · https://doi.org/10.1038/s41467-018-03367-w

• Proteomic Analysis of Single Mammalian Cells Enabled by Microfluidic Nanodroplet Sample Preparation and Ultrasensitive NanoLC‐MS

  Angewandte Chemie International Edition · 2018 · https://doi.org/10.1002/anie.201802843

• Informed-Proteomics: open-source software package for top-down proteomics

  Nature Methods · 2017 · https://doi.org/10.1038/nmeth.4388

• Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands

  Nature Genetics · 2017 · 10.1038/ng.3970

• Formularity: Software for Automated Formula Assignment of Natural and Other Organic Matter from Ultrahigh-Resolution Mass Spectra

  Analytical Chemistry · 2017 · https://doi.org/10.1021/acs.analchem.7b03318

• Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study

  Gastroenterology · 2016 · https://doi.org/10.1053/j.gastro.2016.12.016

• Long-read sequencing and de novo assembly of a Chinese genome

  Nature Communications · 2016 · https://doi.org/10.1038/ncomms12065

• The support of human genetic evidence for approved drug indications

  Nature Genetics · 2015 · 10.1038/ng.3314

• De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies

  Science · 2015 · 10.1126/science.aac9396

• Increased Frequency of De Novo Copy Number Variants in Congenital Heart Disease by Integrative Analysis of Single Nucleotide Polymorphism Array and Exome Sequence Data

  Circulation Research · 2014 · https://doi.org/10.1161/circresaha.115.304458

• Reversed‐phase chromatography with multiple fraction concatenation strategy for proteome profiling of human MCF10A cells

  PROTEOMICS · 2011 · https://doi.org/10.1002/pmic.201000722

• The Genome of the Sea Urchin Strongylocentrotus purpuratus

  Science · 2006 · 10.1126/science.1133609

• Automated 20 kpsi RPLC-MS and MS/MS with Chromatographic Peak Capacities of 1000−1500 and Capabilities in Proteomics and Metabolomics

  Analytical Chemistry · 2005 · https://doi.org/10.1021/ac0483062

• Utilizing Human Blood Plasma for Proteomic Biomarker Discovery

  Journal of Proteome Research · 2005 · https://doi.org/10.1021/pr0500657

• An accurate mass tag strategy for quantitative and high-throughput proteome measurements

  PROTEOMICS · 2002 · https://doi.org/10.1002/1615-9861(200205)2:5<513::aid-prot513>3.0.co;2-w

• Global analysis of the Deinococcus radiodurans proteome by using accurate mass tags

  Proceedings of the National Academy of Sciences · 2002 · https://doi.org/10.1073/pnas.172170199

Current projects

No projects listed.