Yves Moreau

Research interests

Publications

• Associations of Disease-Modifying Therapies With COVID-19 Severity in Multiple Sclerosis

  Neurology · 2021 · 10.1212/wnl.0000000000012753

• Repurposing High-Throughput Image Assays Enables Biological Activity Prediction for Drug Discovery

  Cell chemical biology · 2018 · 10.1016/j.chembiol.2018.01.015

• From hype to reality: data science enabling personalized medicine

  BMC Medicine · 2018 · https://doi.org/10.1186/s12916-018-1122-7

• GRNBoost2 and Arboreto: efficient and scalable inference of gene regulatory networks

  Bioinformatics · 2018 · 10.1093/bioinformatics/bty916

• ACE-inhibition induces a cardioprotective transcriptional response in the metabolic syndrome heart

  Scientific Reports · 2018 · 10.1038/s41598-018-34547-9

• Effective diagnosis of genetic disease by computational phenotype analysis of the disease-associated genome

  Science Translational Medicine · 2014 · 10.1126/scitranslmed.3009262

• Computational tools for prioritizing candidate genes: boosting disease gene discovery

  Nature Reviews Genetics · 2012 · 10.1038/nrg3253

• Microarray analysis reveals abnormal chromosomal complements in over 70% of 14 normally developing human embryos

  Human Reproduction · 2012 · 10.1093/humrep/des362

• Heterozygous missense mutations in SMARCA2 cause Nicolaides-Baraitser syndrome

  Nature Genetics · 2012 · https://doi.org/10.1038/ng.1105

• Optimized Data Fusion for Kernel k-Means Clustering

  IEEE Transactions on Pattern Analysis and Machine Intelligence · 2011 · 10.1109/tpami.2011.255

• A guide to web tools to prioritize candidate genes

  Briefings in Bioinformatics · 2010 · 10.1093/bib/bbq007

• Chromosome instability is common in human cleavage-stage embryos

  Nature Medicine · 2009 · https://doi.org/10.1038/nm.1924

• DECIPHER: Database of Chromosomal Imbalance and Phenotype in Humans Using Ensembl Resources

  The American Journal of Human Genetics · 2009 · 10.1016/j.ajhg.2009.03.010

• Using Ribosomal Protein Genes as Reference: A Tale of Caution

  PLoS ONE · 2008 · 10.1371/journal.pone.0001854

• ENDEAVOUR update: a web resource for gene prioritization in multiple species

  Nucleic Acids Research · 2008 · 10.1093/nar/gkn325

• A human phenome-interactome network of protein complexes implicated in genetic disorders

  Nature Biotechnology · 2007 · https://doi.org/10.1038/nbt1295

• Predicting the prognosis of breast cancer by integrating clinical and microarray data with Bayesian networks

  Bioinformatics · 2006 · 10.1093/bioinformatics/btl230

• Gene prioritization through genomic data fusion

  Nature Biotechnology · 2006 · 10.1038/nbt1203

• Single-cell chromosomal imbalances detection by array CGH

  Nucleic Acids Research · 2006 · 10.1093/nar/gkl336

• BioMart and Bioconductor: a powerful link between biological databases and microarray data analysis

  Computer applications in the biosciences · 2005 · https://doi.org/10.1093/bioinformatics/bti525

• Versatile Gene-Specific Sequence Tags forArabidopsisFunctional Genomics: Transcript Profiling and Reverse Genetics Applications

  Genome Research · 2004 · https://doi.org/10.1101/gr.2544504

• Biclustering microarray data by Gibbs sampling

  Bioinformatics · 2003 · 10.1093/bioinformatics/btg1078

• A Gibbs Sampling Method to Detect Overrepresented Motifs in the Upstream Regions of Coexpressed Genes

  Journal of Computational Biology · 2002 · 10.1089/10665270252935566

• Adaptive quality-based clustering of gene expression profiles

  Bioinformatics · 2002 · 10.1093/bioinformatics/18.5.735

• A higher-order background model improves the detection of promoter regulatory elements by Gibbs sampling

  Bioinformatics · 2001 · 10.1093/bioinformatics/17.12.1113

Current projects

No projects listed.