Walter Berger

Research interests

Publications

• Single-Cell RNA-Seq Reveals Cellular Hierarchies and Impaired Developmental Trajectories in Pediatric Ependymoma

  Cancer Cell · 2020 · 10.1016/j.ccell.2020.06.004

• TERTpromoter mutations are associated with poor prognosis and cell immortalization in meningioma

  Neuro-Oncology · 2018 · 10.1093/neuonc/noy104

• Metal Drugs and the Anticancer Immune Response

  Chemical Reviews · 2018 · 10.1021/acs.chemrev.8b00396

• Podoplanin expression in primary brain tumors induces platelet aggregation and increases risk of venous thromboembolism

  Blood · 2017 · https://doi.org/10.1182/blood-2016-06-720714

• Structure–activity relationships for ruthenium and osmium anticancer agents – towards clinical development

  Chemical Society Reviews · 2017 · https://doi.org/10.1039/c7cs00332c

• Anticancer metal drugs and immunogenic cell death

  Journal of Inorganic Biochemistry · 2016 · 10.1016/j.jinorgbio.2016.06.021

• New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

  Cell · 2016 · https://doi.org/10.1016/j.cell.2016.01.015

• Target profiling of an antimetastatic RAPTA agent by chemical proteomics: relevance to the mode of action

  Chemical Science · 2015 · 10.1039/c4sc03905j

• NKP-1339, the first ruthenium-based anticancer drug on the edge to clinical application

  Chemical Science · 2014 · https://doi.org/10.1039/c3sc53243g

• Spatio‐temporally precise activation of engineered receptor tyrosine kinases by light

  The EMBO Journal · 2014 · 10.15252/embj.201387695

• Organometallic anticancer complexes of lapachol: metal centre-dependent formation of reactive oxygen species and correlation with cytotoxicity

  Chemical Communications · 2013 · 10.1039/c3cc40432c

• Ophiobolin A induces paraptosis-like cell death in human glioblastoma cells by decreasing BKCa channel activity

  Cell Death and Disease · 2013 · 10.1038/cddis.2013.85

• Mechanisms underlying reductant-induced reactive oxygen species formation by anticancer copper(II) compounds

  JBIC Journal of Biological Inorganic Chemistry · 2011 · 10.1007/s00775-011-0864-x

• Anticancer Activity of Metal Complexes: Involvement of Redox Processes

  Antioxidants and Redox Signaling · 2011 · https://doi.org/10.1089/ars.2010.3663

• Intracellular protein binding patterns of the anticancer ruthenium drugs KP1019 and KP1339

  JBIC Journal of Biological Inorganic Chemistry · 2010 · 10.1007/s00775-010-0642-1

• Impact of Metal Coordination on Cytotoxicity of 3-Aminopyridine-2-carboxaldehyde Thiosemicarbazone (Triapine) and Novel Insights into Terminal Dimethylation

  Journal of Medicinal Chemistry · 2009 · 10.1021/jm900528d

• Structure−Activity Relationship Analysis of Novel Derivatives of Narciclasine (an Amaryllidaceae Isocarbostyril Derivative) as Potential Anticancer Agents

  Journal of Medicinal Chemistry · 2009 · 10.1021/jm8013585

• KP1019, A New Redox‐Active Anticancer Agent – Preclinical Development and Results of a Clinical Phase I Study in Tumor Patients

  Chemistry & Biodiversity · 2008 · https://doi.org/10.1002/cbdv.200890195

• Vaults and the major vault protein: Novel roles in signal pathway regulation and immunity

  Cellular and Molecular Life Sciences · 2008 · 10.1007/s00018-008-8364-z

• Resistance against novel anticancer metal compounds: Differences and similarities

  Drug Resistance Updates · 2008 · https://doi.org/10.1016/j.drup.2008.02.002

• Green tea extract and (−)‐epigallocatechin‐3‐gallate, the major tea catechin, exert oxidant but lack antioxidant activities

  The FASEB Journal · 2005 · 10.1096/fj.04-2915fje

• Multidrug resistance markers P-glycoprotein, multidrug resistance protein 1, and lung resistance protein in non-small cell lung cancer: prognostic implications

  Journal of Cancer Research and Clinical Oncology · 2005 · 10.1007/s00432-004-0653-9

• Heterocyclic complexes of ruthenium(III) induce apoptosis in colorectal carcinoma cells

  Journal of Cancer Research and Clinical Oncology · 2004 · 10.1007/s00432-004-0617-0

Current projects

No projects listed.