Michael Grimm

Research interests

Publications

• Impact of gastrointestinal tract variability on oral drug absorption and pharmacokinetics: An UNGAP review

  European Journal of Pharmaceutical Sciences · 2021 · https://doi.org/10.1016/j.ejps.2021.105812

• The Role of Mitochondria in the Mechanisms of Cardiac Ischemia-Reperfusion Injury

  Antioxidants · 2019 · https://doi.org/10.3390/antiox8100454

• Impact of regional differences along the gastrointestinal tract of healthy adults on oral drug absorption: An UNGAP review

  European Journal of Pharmaceutical Sciences · 2019 · https://doi.org/10.1016/j.ejps.2019.04.013

• The mechanisms of pharmacokinetic food-drug interactions – A perspective from the UNGAP group

  European Journal of Pharmaceutical Sciences · 2019 · https://doi.org/10.1016/j.ejps.2019.04.003

• RPC4046, a Monoclonal Antibody Against IL13, Reduces Histologic and Endoscopic Activity in Patients With Eosinophilic Esophagitis

  Gastroenterology · 2018 · https://doi.org/10.1053/j.gastro.2018.10.051

• Navigating the human gastrointestinal tract for oral drug delivery: Uncharted waters and new frontiers

  Advanced Drug Delivery Reviews · 2016 · https://doi.org/10.1016/j.addr.2016.03.009

• Intragastric pH and pressure profiles after intake of the high-caloric, high-fat meal as used for food effect studies

  Journal of Controlled Release · 2015 · https://doi.org/10.1016/j.jconrel.2015.10.022

• Current status and recommendations for use of the frozen elephant trunk technique: a position paper by the Vascular Domain of EACTS

  European Journal of Cardio-Thoracic Surgery · 2015 · https://doi.org/10.1093/ejcts/ezv085

• Current trends in cannulation and neuroprotection during surgery of the aortic arch in Europe

  European Journal of Cardio-Thoracic Surgery · 2014 · https://doi.org/10.1093/ejcts/ezu284

• 2014 ESC Guidelines on the diagnosis and treatment of aortic diseases

  European Heart Journal · 2014 · https://doi.org/10.1093/eurheartj/ehu281

• H9c2 and HL-1 cells demonstrate distinct features of energy metabolism, mitochondrial function and sensitivity to hypoxia-reoxygenation

  Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 2014 · https://doi.org/10.1016/j.bbamcr.2014.11.015

• Investigation of pH and Temperature Profiles in the GI Tract of Fasted Human Subjects Using the Intellicap® System

  Journal of Pharmaceutical Sciences · 2014 · https://doi.org/10.1002/jps.24274

• Ca 2+ /Calmodulin-Dependent Protein Kinase II δ Mediates Myocardial Ischemia/Reperfusion Injury Through Nuclear Factor-κB

  Circulation Research · 2013 · https://doi.org/10.1161/circresaha.112.276915

• Mechanisms of Symptomatic Spinal Cord Ischemia After TEVAR: Insights From the European Registry of Endovascular Aortic Repair Complications (EuREC)

  Journal of Endovascular Therapy · 2012 · https://doi.org/10.1583/11-3578.1

• Changes in mitochondrial redox state, membrane potential and calcium precede mitochondrial dysfunction in doxorubicin-induced cell death

  Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 2011 · https://doi.org/10.1016/j.bbamcr.2011.03.002

• Mitochondrial ROS production under cellular stress: comparison of different detection methods

  Analytical and Bioanalytical Chemistry · 2011 · https://doi.org/10.1007/s00216-011-4764-2

• Natural History of Very Severe Aortic Stenosis

  Circulation · 2009 · https://doi.org/10.1161/circulationaha.109.894170

• β-Adrenergic receptor signaling in the heart: Role of CaMKII

  Journal of Molecular and Cellular Cardiology · 2009 · https://doi.org/10.1016/j.yjmcc.2009.10.016

• Renal Function and Outcome After Continuous Flow Left Ventricular Assist Device Implantation

  The Annals of Thoracic Surgery · 2009 · https://doi.org/10.1016/j.athoracsur.2009.01.022

• The La‐related protein LARP7 is a component of the 7SK ribonucleoprotein and affects transcription of cellular and viral polymerase II genes

  EMBO Reports · 2008 · https://doi.org/10.1038/embor.2008.72

• Left ventricular assist devices decrease fixed pulmonary hypertension in cardiac transplant candidates

  Journal of Thoracic and Cardiovascular Surgery · 2007 · https://doi.org/10.1016/j.jtcvs.2006.08.104

• Superior Prevention of Acute Rejection by Tacrolimus vs. Cyclosporine in Heart Transplant Recipients—A Large European Trial

  American Journal of Transplantation · 2006 · https://doi.org/10.1111/j.1600-6143.2006.01300.x

• Statins as antioxidant therapy for preventing cardiac myocyte hypertrophy

  Journal of Clinical Investigation · 2001 · https://doi.org/10.1172/jci13350

• Complete revascularization in coronary artery bypass grafting with and without cardiopulmonary bypass

  The Annals of Thoracic Surgery · 2001 · https://doi.org/10.1016/s0003-4975(00)02230-x

• Measuring extracellular matrix turnover in the serum of patients with idiopathic or ischemic dilated cardiomyopathy and impact on diagnosis and prognosis

  The American Journal of Cardiology · 1995 · https://doi.org/10.1016/s0002-9149(99)80686-9

Current projects

No projects listed.