Anna S. Berghoff

Research interests

Publications

• Trastuzumab deruxtecan in HER2-positive breast cancer with brain metastases: a single-arm, phase 2 trial

  Nature Medicine · 2022 · https://doi.org/10.1038/s41591-022-01935-8

• EANO–ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up of patients with brain metastasis from solid tumours

  Annals of Oncology · 2021 · 10.1016/j.annonc.2021.07.016

• Prognostic validation and clinical implications of the EANO ESMO classification of leptomeningeal metastasis from solid tumors

  Neuro-Oncology · 2020 · 10.1093/neuonc/noaa298

• Sarcopenia in Neurological Patients: Standard Values for Temporal Muscle Thickness and Muscle Strength Evaluation

  Journal of Clinical Medicine · 2020 · 10.3390/jcm9051272

• CDKN2A/B homozygous deletion is associated with early recurrence in meningiomas

  Acta Neuropathologica · 2020 · https://doi.org/10.1007/s00401-020-02188-w

• Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma

  Nature Genetics · 2020 · https://doi.org/10.1038/s41588-020-0592-7

• Quantitative evidence for early metastatic seeding in colorectal cancer

  Nature Genetics · 2019 · https://doi.org/10.1038/s41588-019-0423-x

• Intertumoral Heterogeneity in SCLC Is Influenced by the Cell Type of Origin

  Cancer Discovery · 2018 · 10.1158/2159-8290.cd-17-0987

• Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate

  Nature Medicine · 2018 · 10.1038/s41591-018-0095-6

• Survival prediction using temporal muscle thickness measurements on cranial magnetic resonance images in patients with newly diagnosed brain metastases

  European Radiology · 2017 · https://doi.org/10.1007/s00330-016-4707-6

• DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis

  The Lancet Oncology · 2017 · 10.1016/s1470-2045(17)30155-9

• Correlation of immune phenotype with IDH mutation in diffuse glioma

  Neuro-Oncology · 2017 · https://doi.org/10.1093/neuonc/nox054

• Impact of Blood–Brain Barrier Integrity on Tumor Growth and Therapy Response in Brain Metastases

  Clinical Cancer Research · 2016 · 10.1158/1078-0432.ccr-16-1327

• Tumor infiltrating lymphocytes and PD-L1 expression in brain metastases of small cell lung cancer (SCLC)

  Journal of Neuro-Oncology · 2016 · https://doi.org/10.1007/s11060-016-2216-8

• Descriptive statistical analysis of a real life cohort of 2419 patients with brain metastases of solid cancers

  ESMO Open · 2016 · https://doi.org/10.1136/esmoopen-2015-000024

• Brain tumour cells interconnect to a functional and resistant network

  Nature · 2015 · 10.1038/nature16071

• Density of tumor-infiltrating lymphocytes correlates with extent of brain edema and overall survival time in patients with brain metastases

  OncoImmunology · 2015 · https://doi.org/10.1080/2162402x.2015.1057388

• Activity of T-DM1 in Her2-positive breast cancer brain metastases

  Clinical & Experimental Metastasis · 2015 · https://doi.org/10.1007/s10585-015-9740-3

• Programmed death ligand 1 expression and tumor-infiltrating lymphocytes in glioblastoma

  Neuro-Oncology · 2014 · https://doi.org/10.1093/neuonc/nou307

• Invasion patterns in brain metastases of solid cancers

  Neuro-Oncology · 2013 · https://doi.org/10.1093/neuonc/not112

• Intrathecal administration of trastuzumab for the treatment of meningeal carcinomatosis in HER2-positive metastatic breast cancer: a systematic review and pooled analysis

  Breast Cancer Research and Treatment · 2013 · https://doi.org/10.1007/s10549-013-2525-y

• Immunohistochemical Detection of the BRAF V600E-mutated Protein in Papillary Thyroid Carcinoma

  The American Journal of Surgical Pathology · 2012 · 10.1097/pas.0b013e318246b527

• BRAFV600E mutant protein is expressed in cells of variable maturation in Langerhans cell histiocytosis

  Blood · 2012 · 10.1182/blood-2012-06-429597

• Brain metastases: pathobiology and emerging targeted therapies

  Acta Neuropathologica · 2012 · https://doi.org/10.1007/s00401-011-0933-9

• Immunohistochemical testing of BRAF V600E status in 1,120 tumor tissue samples of patients with brain metastases

  Acta Neuropathologica · 2011 · 10.1007/s00401-011-0887-y

Current projects

No projects listed.