Dominik Wolf‎

Research interests

Publications

• Comprehensive characterization of the prostate tumor microenvironment identifies CXCR4/CXCL12 crosstalk as a novel antiangiogenic therapeutic target in prostate cancer

  Molecular Cancer · 2022 · 10.1186/s12943-022-01597-7

• High-resolution single-cell atlas reveals diversity and plasticity of tissue-resident neutrophils in non-small cell lung cancer

  Cancer Cell · 2022 · https://doi.org/10.1016/j.ccell.2022.10.008

• Functional Precision Medicine Provides Clinical Benefit in Advanced Aggressive Hematologic Cancers and Identifies Exceptional Responders

  Cancer Discovery · 2021 · https://doi.org/10.1158/2159-8290.cd-21-0538

• Sorafenib Maintenance After Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia With FLT3 –Internal Tandem Duplication Mutation (SORMAIN)

  Journal of Clinical Oncology · 2020 · https://doi.org/10.1200/jco.19.03345

• Overcoming immunotherapy resistance in non-small cell lung cancer (NSCLC) - novel approaches and future outlook

  Molecular Cancer · 2020 · https://doi.org/10.1186/s12943-020-01260-z

• Ropeginterferon alfa-2b versus standard therapy for polycythaemia vera (PROUD-PV and CONTINUATION-PV): a randomised, non-inferiority, phase 3 trial and its extension study

  The Lancet Haematology · 2020 · https://doi.org/10.1016/s2352-3026(19)30236-4

• Tumor Endothelial Cells (TECs) as Potential Immune Directors of the Tumor Microenvironment – New Findings and Future Perspectives

  Frontiers in Cell and Developmental Biology · 2020 · 10.3389/fcell.2020.00766

• Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells

  Nature Medicine · 2018 · https://doi.org/10.1038/nm.4484

• Midostaurin added to chemotherapy and continued single-agent maintenance therapy in acute myeloid leukemia with FLT3-ITD

  Blood · 2018 · https://doi.org/10.1182/blood-2018-08-869453

• Measurable residual disease-guided treatment with azacitidine to prevent haematological relapse in patients with myelodysplastic syndrome and acute myeloid leukaemia (RELAZA2): an open-label, multicentre, phase 2 trial

  The Lancet Oncology · 2018 · https://doi.org/10.1016/s1470-2045(18)30580-1

• Nilotinib-induced vasculopathy: identification of vascular endothelial cells as a primary target site

  Leukemia · 2017 · https://doi.org/10.1038/leu.2017.245

• Bleeding, thrombosis, and anticoagulation in myeloproliferative neoplasms (MPN): analysis from the German SAL-MPN-registry

  Journal of Hematology & Oncology · 2016 · 10.1186/s13045-016-0242-9

• Ruxolitinib in corticosteroid-refractory graft-versus-host disease after allogeneic stem cell transplantation: a multicenter survey

  Leukemia · 2015 · https://doi.org/10.1038/leu.2015.212

• Ropeginterferon alfa-2b, a novel IFNα-2b, induces high response rates with low toxicity in patients with polycythemia vera

  Blood · 2015 · 10.1182/blood-2015-04-637280

• Vascular safety issues in CML patients treated with BCR/ABL1 kinase inhibitors

  Blood · 2014 · https://doi.org/10.1182/blood-2014-09-594432

• The EADC‐ADNI Harmonized Protocol for manual hippocampal segmentation on magnetic resonance: Evidence of validity

  Alzheimer s & Dementia · 2014 · https://doi.org/10.1016/j.jalz.2014.05.1756

• Treatment of Acute Myeloid Leukemia or Myelodysplastic Syndrome Relapse after Allogeneic Stem Cell Transplantation with Azacitidine and Donor Lymphocyte Infusions—A Retrospective Multicenter Analysis from the German Cooperative Transplant Study Group

  Transplantation and Cellular Therapy · 2014 · 10.1016/j.bbmt.2014.12.016

• The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells

  Nature · 2014 · https://doi.org/10.1038/nature12998

• The JAK-inhibitor ruxolitinib impairs dendritic cell function in vitro and in vivo

  Blood · 2013 · https://doi.org/10.1182/blood-2013-03-484642

• Potential Role of Regulatory T Cells in Reversing Obesity-Linked Insulin Resistance and Diabetic Nephropathy

  Diabetes · 2011 · https://doi.org/10.2337/db11-0358

• Pharmacologic inhibition of hepcidin expression reverses anemia of chronic inflammation in rats

  Blood · 2011 · 10.1182/blood-2011-03-345066

• CD4+CD25+ Regulatory T Cells Inhibit Experimental Anti-Glomerular Basement Membrane Glomerulonephritis in Mice

  Journal of the American Society of Nephrology · 2005 · 10.1681/asn.2004100837

• The Expression of the Regulatory T Cell–Specific Forkhead Box Transcription Factor FoxP3 Is Associated with Poor Prognosis in Ovarian Cancer

  Clinical Cancer Research · 2005 · https://doi.org/10.1158/1078-0432.ccr-05-1244

• Adiponectin induces the anti-inflammatory cytokines IL-10 and IL-1RA in human leukocytes

  Biochemical and Biophysical Research Communications · 2004 · https://doi.org/10.1016/j.bbrc.2004.08.145

• Increase of regulatory T cells in the peripheral blood of cancer patients.

  PubMed · 2003

• Importance of Kupffer Cells for T-Cell-Dependent Liver Injury in Mice

  American Journal Of Pathology · 2000 · https://doi.org/10.1016/s0002-9440(10)64804-3

Current projects

No projects listed.