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Ori D. Rotstein

Researcher Next ID · RN-040461

Researcher · Immunology and Microbiology

St. Michael's Hospital

Toronto, Ireland

Accepting doctoral researchersFunding unknown
Works count
419
Citation count
17,681
H-index
77
i10-index
245

Research interests

Immunology and Microbiology
Medicine
Immune Response and Inflammation
Appendicitis Diagnosis and Management
Sepsis Diagnosis and Treatment
Trauma, Hemostasis, Coagulopathy, Resuscitation
Cardiac, Anesthesia and Surgical Outcomes

Publications

  • Postoperative ERAS Interventions Have the Greatest Impact on Optimal Recovery

    Annals of Surgery · 2018 · 10.1097/sla.0000000000002632

  • Prevalence and Causes of Attrition Among Surgical Residents

    JAMA Surgery · 2016 · https://doi.org/10.1001/jamasurg.2016.4086

  • Trial of Short-Course Antimicrobial Therapy for Intraabdominal Infection

    New England Journal of Medicine · 2015 · https://doi.org/10.1056/nejmoa1411162

  • Comparative Operative Outcomes of Early and Delayed Cholecystectomy for Acute Cholecystitis

    Annals of Surgery · 2013 · 10.1097/sla.0b013e3182a5cf36

  • Cell Contact–dependent Regulation of Epithelial–Myofibroblast Transition via the Rho-Rho Kinase-Phospho-Myosin Pathway

    Molecular Biology of the Cell · 2007 · 10.1091/mbc.e06-07-0602

  • Oxidative stress generated by hemorrhagic shock recruits Toll-like receptor 4 to the plasma membrane in macrophages

    The Journal of Experimental Medicine · 2006 · 10.1084/jem.20060943

  • The Immunomodulatory Effects of Hypertonic Saline Resuscitation in Patients Sustaining Traumatic Hemorrhagic Shock

    Annals of Surgery · 2005 · 10.1097/01.sla.0000193608.93127.b1

  • Delayed neutrophil apoptosis in sepsis is associated with maintenance of mitochondrial transmembrane potential and reduced caspase-9 activity*

    Critical Care Medicine · 2004 · 10.1097/01.ccm.0000129975.26905.77

  • Integrity of Cell-Cell Contacts Is a Critical Regulator of TGF-β1-Induced Epithelial-to-Myofibroblast Transition

    American Journal Of Pathology · 2004 · 10.1016/s0002-9440(10)63247-6

  • Pre–B cell colony–enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis

    Journal of Clinical Investigation · 2004 · https://doi.org/10.1172/jci19930

  • Central role for Rho in TGF-β 1 -induced α-smooth muscle actin expression during epithelial-mesenchymal transition

    American Journal of Physiology-Renal Physiology · 2003 · 10.1152/ajprenal.00183.2002

  • Ertapenem Versus Piperacillin/Tazobactam in the Treatment of Complicated Intraabdominal Infections

    Annals of Surgery · 2003 · 10.1097/01.sla.0000048551.32606.73

  • Osmotic stress-induced remodeling of the cortical cytoskeleton

    American Journal of Physiology-Cell Physiology · 2002 · 10.1152/ajpcell.00018.2002

  • Nonopsonic monocyte/macrophage phagocytosis of Plasmodium falciparum–parasitized erythrocytes: a role for CD36 in malarial clearance

    Blood · 2000 · 10.1182/blood.v96.9.3231

  • Tertiary Peritonitis: Clinical Features of a Complex Nosocomial Infection

    World Journal of Surgery · 1998 · 10.1007/s002689900364

  • Hemorrhagic Shock Primes for Increased Expression of Cytokine-Induced Neutrophil Chemoattractant in the Lung: Role in Pulmonary Inflammation Following Lipopolysaccharide

    The Journal of Immunology · 1998 · 10.4049/jimmunol.161.1.440

  • Host Resistance to Intracellular Infection: Mutation of Natural Resistance-associated Macrophage Protein 1 (Nramp1) Impairs Phagosomal Acidification

    The Journal of Experimental Medicine · 1998 · 10.1084/jem.188.2.351

  • Immunomodulatory Effects of Hypertonic Resuscitation on the Development of Lung Inflammation Following Hemorrhagic Shock

    The Journal of Immunology · 1998 · 10.4049/jimmunol.161.11.6288

  • Ribavirin Inhibits Viral-Induced Macrophage Production of TNF, IL-1, the Procoagulant fgl2 Prothrombinase and Preserves Th1 Cytokine Production But Inhibits Th2 Cytokine Response

    The Journal of Immunology · 1998 · https://doi.org/10.4049/jimmunol.160.7.3487

  • Neutrophil apoptosis is modulated by endothelial transmigration and adhesion molecule engagement

    The Journal of Immunology · 1997 · 10.4049/jimmunol.158.2.945

  • Mechanism of Decreased In Vitro Murine Macrophage Cytokine Release After Exposure to Carbon Dioxide

    Annals of Surgery · 1997 · 10.1097/00000658-199708000-00010

  • Results of a Randomized Trial Comparing Sequential Intravenous/Oral Treatment with Ciprofloxacin Plus Metronidazole to Imipenem/Cilastatin for Intra-Abdominal Infections

    Annals of Surgery · 1996 · 10.1097/00000658-199603000-00012

  • Definition of the role of enterococcus in intraabdominal infection: Analysis of a prospective randomized trial

    Surgery · 1995 · 10.1016/s0039-6060(05)80040-6

  • A vacuolar type H(+)-ATPase regulates cytoplasmic pH in murine macrophages.

    Journal of Biological Chemistry · 1990 · 10.1016/s0021-9258(19)39163-x

  • Phagosomal acidification is mediated by a vacuolar-type H(+)-ATPase in murine macrophages.

    Journal of Biological Chemistry · 1990 · 10.1016/s0021-9258(17)45332-4

Current projects

    No projects listed.