John P. Dalton

Research interests

Publications

• A prospective view of animal and human Fasciolosis

  Parasite Immunology · 2016 · https://doi.org/10.1111/pim.12343

• Fasciola hepatica vaccine: We may not be there yet but we’re on the right road

  Veterinary Parasitology · 2015 · https://doi.org/10.1016/j.vetpar.2015.01.004

• The Fasciola hepatica genome: gene duplication and polymorphism reveals adaptation to the host environment and the capacity for rapid evolution

  Genome biology · 2015 · https://doi.org/10.1186/s13059-015-0632-2

• Immunomodulatory molecules of Fasciola hepatica: Candidates for both vaccine and immunotherapeutic development

  Veterinary Parasitology · 2013 · https://doi.org/10.1016/j.vetpar.2013.04.008

• Zoonotic helminth infections with particular emphasis on fasciolosis and other trematodiases

  Philosophical Transactions of the Royal Society B Biological Sciences · 2009 · https://doi.org/10.1098/rstb.2009.0089

• An Integrated Transcriptomics and Proteomics Analysis of the Secretome of the Helminth Pathogen Fasciola hepatica

  Molecular & Cellular Proteomics · 2009 · https://doi.org/10.1074/mcp.m900045-mcp200

• Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase

  Proceedings of the National Academy of Sciences · 2009 · https://doi.org/10.1073/pnas.0807398106

• Helminth 2‐Cys peroxiredoxin drives Th2 responses through a mechanism involving alternatively activated macrophages

  The FASEB Journal · 2008 · https://doi.org/10.1096/fj.08-106278

• The silencing of cysteine proteases in Fasciola hepatica newly excysted juveniles using RNA interference reduces gut penetration

  International Journal for Parasitology · 2007 · https://doi.org/10.1016/j.ijpara.2007.10.007

• Vaccines against the zoonotic trematodes Schistosoma japonicum , Fasciola hepatica and Fasciola gigantica

  Parasitology · 2006 · https://doi.org/10.1017/s0031182006001806

• Cathepsin L1, the Major Protease Involved in Liver Fluke (Fasciola hepatica) Virulence

  Journal of Biological Chemistry · 2004 · https://doi.org/10.1074/jbc.m308831200

• Role of the tegument and gut in nutrient uptake by parasitic platyhelminths

  Canadian Journal of Zoology · 2004 · https://doi.org/10.1139/z03-213

• Thioredoxin Peroxidase Secreted by Fasciola hepatica Induces the Alternative Activation of Macrophages

  Infection and Immunity · 2004 · https://doi.org/10.1128/iai.73.1.166-173.2005

• Fasciola hepatica infection downregulates Th1 responses in mice

  Parasite Immunology · 2000 · https://doi.org/10.1046/j.1365-3024.2000.00290.x

• Vaccination with Cathepsin L Proteinases and with Leucine Aminopeptidase Induces High Levels of Protection against Fascioliasis in Sheep

  Infection and Immunity · 1999 · https://doi.org/10.1128/iai.67.4.1954-1961.1999

• Proteinases and Associated Genes of Parasitic Helminths

  Advances in Parasitology/Advances in parasitology · 1999 · https://doi.org/10.1016/s0065-308x(08)60243-2

• Fasciola hepaticaSuppresses a Protective Th1 Response againstBordetella pertussis

  Infection and Immunity · 1999 · https://doi.org/10.1128/iai.67.10.5372-5378.1999

• Peroxidoxins: A New Antioxidant Family

  Parasitology Today · 1998 · https://doi.org/10.1016/s0169-4758(97)01211-8

• Progress in Development of Liver Fluke Vaccines

  Parasitology Today · 1998 · https://doi.org/10.1016/s0169-4758(98)01245-9

• Immunodiagnosis of Fasciola hepatica infection (fascioliasis) in a human population in the Bolivian Altiplano using purified cathepsin L cysteine proteinase.

  American Journal of Tropical Medicine and Hygiene · 1998 · https://doi.org/10.4269/ajtmh.1998.58.417

• Induction of protective immunity in cattle against infection with Fasciola hepatica by vaccination with cathepsin L proteinases and with hemoglobin

  Infection and Immunity · 1996 · https://doi.org/10.1128/iai.64.12.5066-5074.1996

• Cathepsin L proteinase secreted by Fasciola hepatica in vitro prevents antibody-mediated eosinophil attachment to newly excysted juveniles

  Molecular and Biochemical Parasitology · 1993 · https://doi.org/10.1016/0166-6851(93)90172-t

• Purification of a cathepsin L-like proteinase secreted by adult Fasciola hepatica

  Molecular and Biochemical Parasitology · 1993 · https://doi.org/10.1016/0166-6851(93)90171-s

• Receptor-like specificity of a Plasmodium knowlesi malarial protein that binds to Duffy antigen ligands on erythrocytes.

  The Journal of Experimental Medicine · 1988 · https://doi.org/10.1084/jem.167.6.1873

• A new system of chemical philosophy

  Journal · 1808 · https://doi.org/10.5479/sil.324338.39088000885681

Current projects

No projects listed.