Thomas A. Bayer

Research interests

Publications

• Immune hyperreactivity of Aβ plaque-associated microglia in Alzheimer's disease

  Neurobiology of Aging · 2017 · 10.1016/j.neurobiolaging.2017.03.021

• Endothelial LRP1 transports amyloid-β1–42 across the blood-brain barrier

  Journal of Clinical Investigation · 2015 · https://doi.org/10.1172/jci81108

• Focusing the amyloid cascade hypothesis on N-truncated Abeta peptides as drug targets against Alzheimer’s disease

  Acta Neuropathologica · 2014 · 10.1007/s00401-014-1287-x

• N-truncated amyloid β (Aβ) 4-42 forms stable aggregates and induces acute and long-lasting behavioral deficits

  Acta Neuropathologica · 2013 · 10.1007/s00401-013-1129-2

• Pyroglutamate Amyloid-β (Aβ): A Hatchet Man in Alzheimer Disease

  Journal of Biological Chemistry · 2011 · 10.1074/jbc.r111.288308

• Laser Treatment of Benign Prostatic Obstruction: Basics and Physical Differences

  European Urology · 2011 · https://doi.org/10.1016/j.eururo.2011.10.009

• Motor deficits, neuron loss, and reduced anxiety coinciding with axonal degeneration and intraneuronal Aβ aggregation in the 5XFAD mouse model of Alzheimer's disease

  Neurobiology of Aging · 2010 · https://doi.org/10.1016/j.neurobiolaging.2010.05.027

• Intraneuronal pyroglutamate-Abeta 3–42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model

  Acta Neuropathologica · 2009 · 10.1007/s00401-009-0557-5

• A modified β‐amyloid hypothesis: intraneuronal accumulation of the β‐amyloid peptide – the first step of a fatal cascade

  Journal of Neurochemistry · 2004 · https://doi.org/10.1111/j.1471-4159.2004.02737.x

• Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease

  Journal of Lipid Research · 2004 · 10.1194/jlr.m300320-jlr200

• Massive CA1/2 Neuronal Loss with Intraneuronal and N-Terminal Truncated Aβ42 Accumulation in a Novel Alzheimer Transgenic Model

  American Journal Of Pathology · 2004 · https://doi.org/10.1016/s0002-9440(10)63388-3

• Hippocampal Neuron Loss Exceeds Amyloid Plaque Load in a Transgenic Mouse Model of Alzheimer's Disease

  American Journal Of Pathology · 2004 · 10.1016/s0002-9440(10)63235-x

• Time sequence of maturation of dystrophic neurites associated with Aβ deposits in APP/PS1 transgenic mice

  Experimental Neurology · 2003 · 10.1016/s0014-4886(03)00252-8

• Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Aβ production in APP23 transgenic mice

  Proceedings of the National Academy of Sciences · 2003 · 10.1073/pnas.2332818100

• Intraneuronal Aβ accumulation precedes plaque formation in β-amyloid precursor protein and presenilin-1 double-transgenic mice

  Neuroscience Letters · 2001 · 10.1016/s0304-3940(01)01876-6

• Review of Immunological and Immunopathological Findings in Schizophrenia

  Brain Behavior and Immunity · 2001 · 10.1006/brbi.2001.0648

• Homodimerization of Amyloid Precursor Protein and Its Implication in the Amyloidogenic Pathway of Alzheimer's Disease

  Journal of Biological Chemistry · 2001 · 10.1074/jbc.m105410200

• Key Factors in Alzheimer's Disease: β‐amyloid Precursor Protein Processing, Metabolism and Intraneuronal Transport

  Brain Pathology · 2001 · 10.1111/j.1750-3639.2001.tb00376.x

• Evidence for activation of microglia in patients with psychiatric illnesses

  Neuroscience Letters · 1999 · https://doi.org/10.1016/s0304-3940(99)00545-5

• Genetic and non-genetic vulnerability factors in schizophrenia: the basis of the “Two hit hypothesis”

  Journal of Psychiatric Research · 1999 · https://doi.org/10.1016/s0022-3956(99)00039-4

• A genetic variation of the inflammatory cytokine interleukin-6 delays the initial onset and reduces the risk for sporadic Alzheimer's disease

  Annals of Neurology · 1999 · 10.1002/1531-8249(199905)45:5<666::aid-ana18>3.0.co;2-3

• A long-term study of 370 autotransplanted premolars. Part IV. Root development subsequent to transplantation

  European Journal of Orthodontics · 1990 · 10.1093/ejo/12.1.38

• A long-term study of 370 autotransplanted premolars. Part II. Tooth survival and pulp healing subsequent to transplantation

  European Journal of Orthodontics · 1990 · https://doi.org/10.1093/ejo/12.1.14

• A long-term study of 370 autotransplanted premolars. Part I. Surgical procedures and standardized techniques for monitoring healing

  European Journal of Orthodontics · 1990 · 10.1093/ejo/12.1.3

• Prognosis of root‐fractured permanent incisors — prediction of healing modalities

  Dental Traumatology · 1989 · 10.1111/j.1600-9657.1989.tb00331.x

Current projects

No projects listed.