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Kazuhiro Aoki

Researcher Next ID · RN-040576

Researcher · Biochemistry, Genetics and Molecular Biology

Tokyo Medical and Dental University

Tokyo, Ireland

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Accepting doctoral researchersFunding unknown
Works count
367
Citation count
7,339
H-index
39
i10-index
125

Research interests

Biochemistry, Genetics and Molecular Biology
Medicine
Bone Metabolism and Diseases
Bone health and treatments
Bone health and osteoporosis research
Ear Surgery and Otitis Media
NF-κB Signaling Pathways

Publications

  • Coupling of bone resorption and formation by RANKL reverse signalling

    Nature · 2018 · https://doi.org/10.1038/s41586-018-0482-7

  • Osteoclast formation and differentiation: an overview.

    PubMed · 2012

  • IκBζ regulates TH17 development by cooperating with ROR nuclear receptors

    Nature · 2010 · 10.1038/nature08922

  • Signaling pathway via TNF-α/NF-κB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis

    American Journal of Physiology-Gastrointestinal and Liver Physiology · 2009 · 10.1152/ajpgi.00071.2008

  • Cathepsin K-Dependent Toll-Like Receptor 9 Signaling Revealed in Experimental Arthritis

    Science · 2008 · https://doi.org/10.1126/science.1150110

  • Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2−/− mice

    The Journal of Cell Biology · 2007 · 10.1083/jcb.200701148

  • A TNF receptor loop peptide mimic blocks RANK ligand–induced signaling, bone resorption, and bone loss

    Journal of Clinical Investigation · 2006 · 10.1172/jci22513

  • Regulation of osteoclast differentiation and function by the CaMK-CREB pathway

    Nature Medicine · 2006 · https://doi.org/10.1038/nm1515

  • Inhibition of RANKL-Induced Osteoclastogenesis by (−)-DHMEQ, a Novel NF-κB Inhibitor, Through Downregulation of NFATc1

    Journal of Bone and Mineral Research · 2005 · 10.1359/jbmr.041213

  • Selective inhibition of NF-κB blocks osteoclastogenesis and prevents inflammatory bone destruction in vivo

    Nature Medicine · 2004 · https://doi.org/10.1038/nm1054

  • Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2

    Genes & Development · 2004 · 10.1101/gad.1167304

  • Overexpression of ΔFosB transcription factor(s) increases bone formation and inhibits adipogenesis

    Nature Medicine · 2000 · https://doi.org/10.1038/79683

  • Effects of surface roughness of titanium implants on bone remodeling activity of femur in rabbits

    Bone · 1997 · 10.1016/s8756-3282(97)00204-4

Current projects

    No projects listed.