Richard W. Costello

Research interests

Publications

• Eosinophilic and Noneosinophilic Asthma

  CHEST Journal · 2021 · https://doi.org/10.1016/j.chest.2021.04.013

• Composite type-2 biomarker strategy versus a symptom–risk-based algorithm to adjust corticosteroid dose in patients with severe asthma: a multicentre, single-blind, parallel group, randomised controlled trial

  The Lancet Respiratory Medicine · 2020 · 10.1016/s2213-2600(20)30397-0

• Characterization of the Inflammatory Response to Severe COVID-19 Illness

  American Journal of Respiratory and Critical Care Medicine · 2020 · https://doi.org/10.1164/rccm.202005-1583oc

• Remotely Monitored Therapy and Nitric Oxide Suppression Identifies Nonadherence in Severe Asthma

  American Journal of Respiratory and Critical Care Medicine · 2018 · 10.1164/rccm.201806-1182oc

• Digital technologies and adherence in respiratory diseases: the road ahead

  European Respiratory Journal · 2018 · 10.1183/13993003.01147-2018

• A randomised clinical trial of feedback on inhaler adherence and technique in patients with severe uncontrolled asthma

  European Respiratory Journal · 2018 · 10.1183/13993003.01126-2017

• Eosinophils increase airway sensory nerve density in mice and in human asthma

  Science Translational Medicine · 2018 · 10.1126/scitranslmed.aar8477

• Objective Assessment of Adherence to Inhalers by Patients with Chronic Obstructive Pulmonary Disease

  American Journal of Respiratory and Critical Care Medicine · 2016 · 10.1164/rccm.201604-0733oc

• The use of multiple respiratory inhalers requiring different inhalation techniques has an adverse effect on COPD outcomes

  International Journal of COPD · 2016 · 10.2147/copd.s117196

• Increased expression of bronchial epithelial transient receptor potential vanilloid 1 channels in patients with severe asthma

  Journal of Allergy and Clinical Immunology · 2013 · 10.1016/j.jaci.2013.09.016

• Short term and long term effects of pulmonary rehabilitation on physical activity in COPD

  Respiratory Medicine · 2012 · 10.1016/j.rmed.2012.08.016

• Impact of Cough Across Different Chronic Respiratory Diseases

  CHEST Journal · 2007 · 10.1378/chest.07-0141

• Extending a home from hospital care programme for COPD exacerbations to include pulmonary rehabilitation

  Respiratory Medicine · 2005 · 10.1016/j.rmed.2005.02.033

• Lung Mechanics and Dyspnea during Exacerbations of Chronic Obstructive Pulmonary Disease

  American Journal of Respiratory and Critical Care Medicine · 2005 · 10.1164/rccm.200504-595oc

• Use of Sniff Nasal-Inspiratory Force to Predict Survival in Amyotrophic Lateral Sclerosis

  American Journal of Respiratory and Critical Care Medicine · 2004 · https://doi.org/10.1164/rccm.200403-314oc

• Eosinophil recruitment to the airway nerves

  Journal of Allergy and Clinical Immunology · 2001 · 10.1067/mai.2001.112940

• Reversible hypercapnia in chronic obstructive pulmonary disease: A distinct pattern of respiratory failure with a favorable prognosis

  The American Journal of Medicine · 1997 · 10.1016/s0002-9343(97)00017-x

• Pretreatment with antibody to eosinophil major basic protein prevents hyperresponsiveness by protecting neuronal M2 muscarinic receptors in antigen-challenged guinea pigs.

  Journal of Clinical Investigation · 1997 · 10.1172/jci119763

• Localization of eosinophils to airway nerves and effect on neuronal M2 muscarinic receptor function

  American Journal of Physiology-Lung Cellular and Molecular Physiology · 1997 · 10.1152/ajplung.1997.273.1.l93

Current projects

No projects listed.