Roisín M. Connolly

Research interests

Publications

• Trastuzumab deruxtecan in HER2-positive advanced breast cancer with or without brain metastases: a phase 3b/4 trial

  Nature Medicine · 2024 · https://doi.org/10.1038/s41591-024-03261-7

• The PD-1- and LAG-3-targeting bispecific molecule tebotelimab in solid tumors and hematologic cancers: a phase 1 trial

  Nature Medicine · 2023 · 10.1038/s41591-023-02593-0

• Phase 1 study of single-agent WNT974, a first-in-class Porcupine inhibitor, in patients with advanced solid tumours

  British Journal of Cancer · 2021 · https://doi.org/10.1038/s41416-021-01389-8

• TBCRC 022: A Phase II Trial of Neratinib and Capecitabine for Patients With Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer and Brain Metastases

  Journal of Clinical Oncology · 2019 · https://doi.org/10.1200/jco.18.01511

• Entinostat Converts Immune-Resistant Breast and Pancreatic Cancers into Checkpoint-Responsive Tumors by Reprogramming Tumor-Infiltrating MDSCs

  Cancer Immunology Research · 2018 · https://doi.org/10.1158/2326-6066.cir-18-0070

• Entinostat: a promising treatment option for patients with advanced breast cancer

  Future Oncology · 2017 · https://doi.org/10.2217/fon-2016-0526

• ESMO / ASCO Recommendations for a Global Curriculum in Medical Oncology Edition 2016

  ESMO Open · 2016 · 10.1136/esmoopen-2016-000097

• Translational Breast Cancer Research Consortium (TBCRC) 022: A Phase II Trial of Neratinib for Patients With Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer and Brain Metastases

  Journal of Clinical Oncology · 2016 · https://doi.org/10.1200/jco.2015.63.0343

• Combination Epigenetic Therapy in Advanced Breast Cancer with 5-Azacitidine and Entinostat: A Phase II National Cancer Institute/Stand Up to Cancer Study

  Clinical Cancer Research · 2016 · https://doi.org/10.1158/1078-0432.ccr-16-1729

• FDG-PET/CT and MRI for Evaluation of Pathologic Response to Neoadjuvant Chemotherapy in Patients With Breast Cancer: A Meta-Analysis of Diagnostic Accuracy Studies

  The Oncologist · 2016 · https://doi.org/10.1634/theoncologist.2015-0353

• Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers

  Oncotarget · 2014 · https://doi.org/10.18632/oncotarget.1782

• Treatment of HER2-positive breast cancer

  The Breast · 2013 · 10.1016/j.breast.2013.11.011

• Molecular Pathways: Current Role and Future Directions of the Retinoic Acid Pathway in Cancer Prevention and Treatment

  Clinical Cancer Research · 2013 · https://doi.org/10.1158/1078-0432.ccr-12-3175

• Beta Blockers and Breast Cancer Mortality: A Population- Based Study

  Journal of Clinical Oncology · 2011 · https://doi.org/10.1200/jco.2010.33.5422

• Early discontinuation of tamoxifen

  Cancer · 2007 · https://doi.org/10.1002/cncr.22485

Current projects

No projects listed.