Owen Smith

Research interests

Publications

• Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes

  Nature Medicine · 2021 · 10.1038/s41591-021-01511-6

• Adolescents and young adults (AYA) with cancer: a position paper from the AYA Working Group of the European Society for Medical Oncology (ESMO) and the European Society for Paediatric Oncology (SIOPE)

  ESMO Open · 2021 · https://doi.org/10.1016/j.esmoop.2021.100096

• The clinical landscape for AAV gene therapies

  Nature Reviews Drug Discovery · 2021 · https://doi.org/10.1038/d41573-021-00017-7

• Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes

  Nature Medicine · 2021 · 10.1038/s41591-021-01511-6

• Flash survey on severe acute respiratory syndrome coronavirus-2 infections in paediatric patients on anticancer treatment

  European Journal of Cancer · 2020 · 10.1016/j.ejca.2020.03.021

• RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia

  Nature Communications · 2017 · 10.1038/s41467-017-02177-w

• Prevalence, clinical characteristics, and prognosis of GATA2-related myelodysplastic syndromes in children and adolescents

  Blood · 2015 · https://doi.org/10.1182/blood-2015-09-669937

• Collaborative Efforts Driving Progress in Pediatric Acute Myeloid Leukemia

  Journal of Clinical Oncology · 2015 · https://doi.org/10.1200/jco.2015.62.8289

• Improved Outcome in Pediatric Relapsed Acute Myeloid Leukemia: Results of a Randomized Trial on Liposomal Daunorubicin by the International BFM Study Group

  Journal of Clinical Oncology · 2013 · https://doi.org/10.1200/jco.2012.43.7384

• Partial MCM4 deficiency in patients with growth retardation, adrenal insufficiency, and natural killer cell deficiency

  Journal of Clinical Investigation · 2012 · https://doi.org/10.1172/jci61014

• Elevated factor VIII levels and risk of venous thrombosis

  British Journal of Haematology · 2012 · https://doi.org/10.1111/j.1365-2141.2012.09134.x

• X-linked lymphoproliferative disease due to SAP/SH2D1A deficiency: a multicenter study on the manifestations, management and outcome of the disease

  Blood · 2010 · https://doi.org/10.1182/blood-2010-06-284935

• Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome

  The Lancet · 2008 · https://doi.org/10.1016/s0140-6736(08)61341-0

• Circulating microparticles: pathophysiology and clinical implications

  Blood Reviews · 2006 · https://doi.org/10.1016/j.blre.2006.09.001

• An open-label study of the role of adjuvant hemostatic support with protein C replacement therapy in purpura fulminans–associated meningococcemia

  Blood · 2000 · 10.1182/blood.v96.12.3719

• Activated protein C inhibits lipopolysaccharide‐induced nuclear translocation of nuclear factor κB (NF‐κB) and tumour necrosis factor α (TNF‐α) production in the THP‐1 monocytic cell line

  British Journal of Haematology · 2000 · 10.1046/j.1365-2141.2000.02128.x

• Haematological abnormalities in Shwachman‐Diamond syndrome

  British Journal of Haematology · 1996 · 10.1046/j.1365-2141.1996.d01-1788.x

• Progress in the Diagnosis and Management of Aspergillosis in Bone Marrow Transplantation: 13 Years' Experience

  Clinical Infectious Diseases · 1993 · 10.1093/clinids/17.3.397

Current projects

No projects listed.