Ursula Fearon

Research interests

Publications

• STAT3 Mediates the Differential Effects of Oncostatin M and TNFα on RA Synovial Fibroblast and Endothelial Cell Function

  Frontiers in Immunology · 2019 · 10.3389/fimmu.2019.02056

• JAK / STAT Blockade Alters Synovial Bioenergetics, Mitochondrial Function, and Proinflammatory Mediators in Rheumatoid Arthritis

  Arthritis & Rheumatology · 2018 · 10.1002/art.40569

• Integrative analysis reveals CD38 as a therapeutic target for plasma cell-rich pre-disease and established rheumatoid arthritis and systemic lupus erythematosus

  Arthritis Research & Therapy · 2018 · 10.1186/s13075-018-1578-z

• Hypoxia, oxidative stress and inflammation

  Free Radical Biology and Medicine · 2018 · https://doi.org/10.1016/j.freeradbiomed.2018.03.042

• The Utility and Limitations of CRP, ESR and DAS28-CRP in Appraising Disease Activity in Rheumatoid Arthritis

  Frontiers in Medicine · 2018 · 10.3389/fmed.2018.00185

• The pathogenesis of psoriatic arthritis

  The Lancet · 2018 · https://doi.org/10.1016/s0140-6736(18)30830-4

• Ex-Th17 (Nonclassical Th1) Cells Are Functionally Distinct from Classical Th1 and Th17 Cells and Are Not Constrained by Regulatory T Cells

  The Journal of Immunology · 2017 · 10.4049/jimmunol.1600737

• Resolution of inflammation by interleukin-9-producing type 2 innate lymphoid cells

  Nature Medicine · 2017 · https://doi.org/10.1038/nm.4373

• The role of metabolism in the pathogenesis of osteoarthritis

  Nature Reviews Rheumatology · 2017 · https://doi.org/10.1038/nrrheum.2017.50

• Synovial tissue research: a state-of-the-art review

  Nature Reviews Rheumatology · 2017 · 10.1038/nrrheum.2017.115

• CD40L-Dependent Pathway Is Active at Various Stages of Rheumatoid Arthritis Disease Progression

  The Journal of Immunology · 2017 · 10.4049/jimmunol.1601988

• Cellular and molecular perspectives in rheumatoid arthritis

  Seminars in Immunopathology · 2017 · 10.1007/s00281-017-0633-1

• Hypoxia, mitochondrial dysfunction and synovial invasiveness in rheumatoid arthritis

  Nature Reviews Rheumatology · 2016 · https://doi.org/10.1038/nrrheum.2016.69

• Dysregulated bioenergetics: a key regulator of joint inflammation

  Annals of the Rheumatic Diseases · 2016 · 10.1136/annrheumdis-2015-208476

• Tofacitinib regulates synovial inflammation in psoriatic arthritis, inhibiting STAT activation and induction of negative feedback inhibitors

  Annals of the Rheumatic Diseases · 2015 · 10.1136/annrheumdis-2014-207201

• Hypoxia and STAT3 signalling interactions regulate pro-inflammatory pathways in rheumatoid arthritis

  Annals of the Rheumatic Diseases · 2014 · 10.1136/annrheumdis-2013-204105

• Notch signalling pathways mediate synovial angiogenesis in response to vascular endothelial growth factor and angiopoietin 2

  Annals of the Rheumatic Diseases · 2012 · 10.1136/annrheumdis-2012-201978

• Macrophages in Synovial Inflammation

  Frontiers in Immunology · 2011 · 10.3389/fimmu.2011.00052

• Angiogenesis and blood vessel stability in inflammatory arthritis

  Arthritis & Rheumatism · 2010 · 10.1002/art.27287

• Synovial tissue hypoxia and inflammation in vivo

  Annals of the Rheumatic Diseases · 2010 · 10.1136/ard.2009.119776

• Synovial Tissue Sublining CD68 Expression Is a Biomarker of Therapeutic Response in Rheumatoid Arthritis Clinical Trials: Consistency Across Centers

  The Journal of Rheumatology · 2009 · 10.3899/jrheum.090348

• Human rheumatoid arthritis tissue production of IL-17A drives matrix and cartilage degradation: synergy with tumour necrosis factor-α, Oncostatin M and response to biologic therapies

  Arthritis Research & Therapy · 2009 · 10.1186/ar2772

• Acute‐phase serum amyloid A stimulation of angiogenesis, leukocyte recruitment, and matrix degradation in rheumatoid arthritis through an NF‐κB–dependent signal transduction pathway

  Arthritis & Rheumatism · 2005 · 10.1002/art.21518

• Turnover of type II collagen and aggrecan in cartilage matrix at the onset of inflammatory arthritis in humans: Relationship to mediators of systemic and local inflammation

  Arthritis & Rheumatism · 2003 · 10.1002/art.11331

• Angiopoietins, growth factors, and vascular morphology in early arthritis.

  PubMed · 2003

Current projects

No projects listed.