Patrı́cio Soares-da-Silva

Research interests

Publications

• Opicapone as Adjunct to Levodopa Therapy in Patients With Parkinson Disease and Motor Fluctuations

  JAMA Neurology · 2016 · https://doi.org/10.1001/jamaneurol.2016.4703

• Opicapone as an adjunct to levodopa in patients with Parkinson's disease and end-of-dose motor fluctuations: a randomised, double-blind, controlled trial

  The Lancet Neurology · 2015 · https://doi.org/10.1016/s1474-4422(15)00336-1

• Eslicarbazepine and the enhancement of slow inactivation of voltage-gated sodium channels: A comparison with carbamazepine, oxcarbazepine and lacosamide

  Neuropharmacology · 2014 · https://doi.org/10.1016/j.neuropharm.2014.09.008

• Pharmacokinetics and drug interactions of eslicarbazepine acetate

  Epilepsia · 2012 · https://doi.org/10.1111/j.1528-1167.2012.03519.x

• Eslicarbazepine acetate as adjunctive therapy in adult patients with partial epilepsy

  Epilepsy Research · 2010 · https://doi.org/10.1016/j.eplepsyres.2010.01.014

• Discovery of a Long-Acting, Peripherally Selective Inhibitor of Catechol-O-methyltransferase

  Journal of Medicinal Chemistry · 2010 · https://doi.org/10.1021/jm1001524

• Pharmacokinetic and safety profile oftrans‐resveratrol in a rising multiple‐dose study in healthy volunteers

  Molecular Nutrition & Food Research · 2009 · https://doi.org/10.1002/mnfr.200800177

• Efficacy and safety of eslicarbazepine acetate as adjunctive treatment in adults with refractory partial‐onset seizures: A randomized, double‐blind, placebo‐controlled, parallel‐group phase III study

  Epilepsia · 2009 · https://doi.org/10.1111/j.1528-1167.2008.01946.x

• Efficacy and safety of 800 and 1200 mg eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures

  Acta Neurologica Scandinavica · 2009 · https://doi.org/10.1111/j.1600-0404.2009.01218.x

• Dopamine 5 receptor mediates Ang II type 1 receptor degradation via a ubiquitin-proteasome pathway in mice and human cells

  Journal of Clinical Investigation · 2008 · https://doi.org/10.1172/jci33637c1

• Eslicarbazepine Acetate: A Double‐blind, Add‐on, Placebo‐controlled Exploratory Trial in Adult Patients with Partial‐onset Seizures

  Epilepsia · 2007 · https://doi.org/10.1111/j.1528-1167.2007.00984.x

• Catechol‐ O ‐methyltransferase and Its Inhibitors in Parkinson's Disease

  CNS Drug Reviews · 2007 · https://doi.org/10.1111/j.1527-3458.2007.00020.x

• Eslicarbazepine Acetate (BIA 2-093)

  Neurotherapeutics · 2007 · https://doi.org/10.1016/j.nurt.2006.10.005

• Decrease of adenosine A 1 receptor density and of adenosine neuromodulation in the hippocampus of kindled rats

  European Journal of Neuroscience · 2003 · https://doi.org/10.1046/j.1460-9568.2003.02815.x

• Mechanisms of Action of Carbamazepine and Its Derivatives, Oxcarbazepine, BIA 2-093, and BIA 2-024

  Neurochemical Research · 2002 · https://doi.org/10.1023/a:1014814924965

• Mice Lacking D5Dopamine Receptors Have Increased Sympathetic Tone and Are Hypertensive

  Journal of Neuroscience · 2002 · https://doi.org/10.1523/jneurosci.22-24-10801.2002

• Impaired Synthesis or Cellular Storage of Norepinephrine, Dopamine, and 5-Hydroxytryptamine in Human Inflammatory Bowel Disease

  Digestive Diseases and Sciences · 2002 · https://doi.org/10.1023/a:1013256629600

• Anticonvulsant and Sodium Channel-Blocking Properties of Novel 10,11-Dihydro-5H-dibenz[b,f]azepine-5-carboxamide Derivatives

  Journal of Medicinal Chemistry · 1999 · https://doi.org/10.1021/jm980627g

Current projects

No projects listed.