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Maria João Saraiva

Researcher Next ID · RN-041108

Researcher · Biochemistry, Genetics and Molecular Biology

i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto

Porto, Portugal

Accepting doctoral researchersFunding unknown
Works count
394
Citation count
18,096
H-index
72
i10-index
238

Research interests

Biochemistry, Genetics and Molecular Biology
Medicine
Amyloidosis: Diagnosis, Treatment, Outcomes
Alzheimer's disease research and treatments
Cellular transport and secretion
Protein Kinase Regulation and GTPase Signaling
Coagulation, Bradykinin, Polyphosphates, and Angioedema

Publications

  • Amyloid nomenclature 2024: update, novel proteins, and recommendations by the International Society of Amyloidosis (ISA) Nomenclature Committee

    Amyloid · 2024 · 10.1080/13506129.2024.2405948

  • Amyloid nomenclature 2022: update, novel proteins, and recommendations by the International Society of Amyloidosis (ISA) Nomenclature Committee

    Amyloid · 2022 · 10.1080/13506129.2022.2147636

  • Amyloid nomenclature 2020: update and recommendations by the International Society of Amyloidosis (ISA) nomenclature committee

    Amyloid · 2020 · https://doi.org/10.1080/13506129.2020.1835263

  • Amyloid nomenclature 2018: recommendations by the International Society of Amyloidosis (ISA) nomenclature committee

    Amyloid · 2018 · https://doi.org/10.1080/13506129.2018.1549825

  • Amyloid fibril proteins and amyloidosis: chemical identification and clinical classification International Society of Amyloidosis 2016 Nomenclature Guidelines

    Amyloid · 2016 · https://doi.org/10.1080/13506129.2016.1257986

  • Transthyretin: a multifaceted protein

    BioMolecular Concepts · 2014 · 10.1515/bmc-2013-0038

  • Nomenclature 2014: Amyloid fibril proteins and clinical classification of the amyloidosis

    Amyloid · 2014 · https://doi.org/10.3109/13506129.2014.964858

  • Doxycycline plus tauroursodeoxycholic acid for transthyretin amyloidosis: a phase II study

    Amyloid · 2012 · 10.3109/13506129.2012.678508

  • Amyloid fibril protein nomenclature: 2012 recommendations from the Nomenclature Committee of the International Society of Amyloidosis

    Amyloid · 2012 · 10.3109/13506129.2012.734345

  • Natural polyphenols inhibit different steps of the process of transthyretin (TTR) amyloid fibril formation

    FEBS Letters · 2011 · 10.1016/j.febslet.2011.06.030

  • Synergy of combined Doxycycline/TUDCA treatment in lowering Transthyretin deposition and associated biomarkers: studies in FAP mouse models

    Journal of Translational Medicine · 2010 · 10.1186/1479-5876-8-74

  • Amyloid fibril protein nomenclature: 2010 recommendations from the nomenclature committee of the International Society of Amyloidosis

    Amyloid · 2010 · 10.3109/13506129.2010.526812

  • Transthyretin binding to A‐Beta peptide – Impact on A‐Beta fibrillogenesis and toxicity

    FEBS Letters · 2008 · 10.1016/j.febslet.2008.02.034

  • A primer of amyloid nomenclature

    Amyloid · 2007 · 10.1080/13506120701460923

  • Doxycycline disrupts transthyretin amyloid: evidence from studies in a FAP transgenic mice model

    The FASEB Journal · 2006 · 10.1096/fj.05-4509com

  • Amyloid: Toward terminology clarification Report from the Nomenclature Committee of the International Society of Amyloidosis

    Amyloid · 2005 · 10.1080/13506120500032196

  • Amyloid Fibril Protein Nomenclature - 2002

    Amyloid · 2002 · 10.3109/13506120209114823

  • Tetramer Dissociation and Monomer Partial Unfolding Precedes Protofibril Formation in Amyloidogenic Transthyretin Variants

    Journal of Biological Chemistry · 2001 · 10.1074/jbc.m101024200

  • Deposition of Transthyretin in Early Stages of Familial Amyloidotic Polyneuropathy

    American Journal Of Pathology · 2001 · 10.1016/s0002-9440(10)63050-7

  • Familial Amyloid Polyneuropathy: Receptor for Advanced Glycation End Products-Dependent Triggering of Neuronal Inflammatory and Apoptotic Pathways

    Journal of Neuroscience · 2001 · 10.1523/jneurosci.21-19-07576.2001

  • Transthyretin mutations in hyperthyroxinemia and amyloid diseases

    Human Mutation · 2001 · 10.1002/humu.1132

  • Interaction of the Receptor for Advanced Glycation End Products (RAGE) with Transthyretin Triggers Nuclear Transcription Factor kB (NF-kB) Activation

    Laboratory Investigation · 2000 · 10.1038/labinvest.3780116

  • The Tetrameric Protein Transthyretin Dissociates to a Non-native Monomer in Solution

    Journal of Biological Chemistry · 1999 · 10.1074/jbc.274.46.32943

  • Geographical distribution of TTR met30 carriers in northern Sweden: discrepancy between carrier frequency and prevalence rate.

    Journal of Medical Genetics · 1994 · 10.1136/jmg.31.5.351

  • Amyloid fibril protein in familial amyloidotic polyneuropathy, Portuguese type. Definition of molecular abnormality in transthyretin (prealbumin).

    Journal of Clinical Investigation · 1984 · https://doi.org/10.1172/jci111390

Current projects

    No projects listed.