Chris H. Senanayake

Research interests

Publications

• P-Chiral Phosphorus Ligands Based on a 2,3-Dihydrobenzo[ d ][1,3]oxaphosphole Motif for Asymmetric Catalysis

  Accounts of Chemical Research · 2019 · https://doi.org/10.1021/acs.accounts.9b00029

• Ligand-Enabled γ-C(sp3)–H Activation of Ketones

  Journal of the American Chemical Society · 2018 · 10.1021/jacs.8b01359

• Nickel‐Catalyzed Esterification of Aliphatic Amides

  Angewandte Chemie International Edition · 2016 · 10.1002/anie.201607856

• The Reaction of Grignard Reagents with Bunte Salts: A Thiol-Free Synthesis of Sulfides

  Organic Letters · 2014 · 10.1021/ol500067f

• Overcoming barriers to green chemistry in the pharmaceutical industry – the Green Aspiration Level™ concept

  Green Chemistry · 2014 · https://doi.org/10.1039/c4gc01563k

• Efficient Asymmetric Synthesis of P -Chiral Phosphine Oxides via Properly Designed and Activated Benzoxazaphosphinine-2-oxide Agents

  Journal of the American Chemical Society · 2013 · 10.1021/ja312352p

• Efficient Syntheses of Korupensamines A, B and Michellamine B by Asymmetric Suzuki-Miyaura Coupling Reactions

  Journal of the American Chemical Society · 2013 · https://doi.org/10.1021/ja409669r

• Efficient Chiral Monophosphorus Ligands for Asymmetric Suzuki–Miyaura Coupling Reactions

  Organic Letters · 2012 · 10.1021/ol300659d

• The Eight Criteria Defining a Good Chemical Manufacturing Process

  Organic Process Research & Development · 2012 · 10.1021/op300144g

• The Growing Impact of Catalysis in the Pharmaceutical Industry

  Advanced Synthesis & Catalysis · 2011 · https://doi.org/10.1002/adsc.201100488

• Efficient Monophosphorus Ligands for Palladium-Catalyzed Miyaura Borylation

  Organic Letters · 2011 · 10.1021/ol2000556

• A General and Special Catalyst for Suzuki–Miyaura Coupling Processes

  Angewandte Chemie International Edition · 2010 · 10.1002/anie.201002404

• Room Temperature Palladium-Catalyzed Cross Coupling of Aryltrimethylammonium Triflates with Aryl Grignard Reagents

  Organic Letters · 2010 · 10.1021/ol1018739

• Copper Catalyzed Asymmetric Propargylation of Aldehydes

  Journal of the American Chemical Society · 2010 · 10.1021/ja103312x

• Novel, Tunable, and Efficient Chiral Bisdihydrobenzooxaphosphole Ligands for Asymmetric Hydrogenation

  Organic Letters · 2009 · 10.1021/ol9025815

• Organometallic methods for the synthesis and functionalization of azaindoles

  Chemical Society Reviews · 2007 · 10.1039/b607868k

• Activation of TMSCN by N-Heterocyclic Carbenes for Facile Cyanosilylation of Carbonyl Compounds

  The Journal of Organic Chemistry · 2006 · 10.1021/jo052206u

• A Practical Mild, One-Pot, Regiospecific Synthesis of 2,3-Disubstituted Indoles via Consecutive Sonogashira and Cacchi Reactions

  Organic Letters · 2006 · 10.1021/ol061136q

• Activation of TMSCN by N‐Heterocyclic Carbenes for Facile Cyanosilylation of Carbonyl Compounds.

  ChemInform · 2006 · 10.1002/chin.200625094

• Asymmetric Synthesis of Active Pharmaceutical Ingredients

  Chemical Reviews · 2006 · https://doi.org/10.1021/cr040700c

• A Superior Method for the Reduction of Secondary Phosphine Oxides

  Organic Letters · 2005 · 10.1021/ol0517832

• N-Heterocyclic Carbene Catalyzed Trifluoromethylation of Carbonyl Compounds

  Organic Letters · 2005 · 10.1021/ol050568i

• The First Regioselective Palladium-Catalyzed Indolization of 2-Bromo- or 2-Chloroanilines with Internal Alkynes: A New Approach to 2,3-Disubstituted Indoles

  Organic Letters · 2004 · 10.1021/ol048114t

• The behavior of indene oxide in the ritter reaction: A simple route to cis-aminoindanol

  Tetrahedron Letters · 1995 · 10.1016/0040-4039(95)00696-a

• Improved Fischer Indole Reaction for the Preparation of N,N-Dimethyltryptamines: Synthesis of L-695,894, a Potent 5-HT1D Receptor Agonist

  The Journal of Organic Chemistry · 1994 · 10.1021/jo00092a046

Current projects

No projects listed.