Antonı́n Holý

Research interests

Publications

• Acyclic nucleoside phosphonates: a key class of antiviral drugs

  Nature Reviews Drug Discovery · 2005 · https://doi.org/10.1038/nrd1877

• Synthesis and Cytostatic Activity of Substituted 6-Phenylpurine Bases and Nucleosides: Application of the Suzuki−Miyaura Cross-Coupling Reactions of 6-Chloropurine Derivatives with Phenylboronic Acids

  Journal of Medicinal Chemistry · 2000 · https://doi.org/10.1021/jm991167+

• Structure−Antiviral Activity Relationship in the Series of Pyrimidine and Purine N-[2-(2-Phosphonomethoxy)ethyl] Nucleotide Analogues. 1. Derivatives Substituted at the Carbon Atoms of the Base

  Journal of Medicinal Chemistry · 1999 · https://doi.org/10.1021/jm9811256

• Differential antiherpesvirus and antiretrovirus effects of the (S) and (R) enantiomers of acyclic nucleoside phosphonates: potent and selective in vitro and in vivo antiretrovirus activities of (R)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurine

  Antimicrobial Agents and Chemotherapy · 1993 · https://doi.org/10.1128/aac.37.2.332

• Phosphonylmethoxyethyl purine derivatives, a new class of anti-human immunodeficiency virus agents

  Antimicrobial Agents and Chemotherapy · 1988 · https://doi.org/10.1128/aac.32.7.1025

• Antiviral activity of phosphonylmethoxyalkyl derivatives of purine and pyrimidines

  Antiviral Research · 1987 · https://doi.org/10.1016/s0166-3542(87)80004-9

• A novel selective broad-spectrum anti-DNA virus agent

  Nature · 1986 · https://doi.org/10.1038/323464a0

Current projects

No projects listed.