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Marián Hajdúch

Researcher Next ID · RN-041706

Researcher · Biochemistry, Genetics and Molecular Biology

University Hospital Olomouc

Olomouc, Czechia

Accepting doctoral researchersFunding unknown
Works count
751
Citation count
15,727
H-index
59
i10-index
281

Research interests

Biochemistry, Genetics and Molecular Biology
Chemistry
Medicine
Natural product bioactivities and synthesis
Cancer Cells and Metastasis
HIV/AIDS drug development and treatment
Synthesis and biological activity
Cancer Genomics and Diagnostics

Publications

  • Circulating tumor nucleic acids: biology, release mechanisms, and clinical relevance

    Molecular Cancer · 2023 · 10.1186/s12943-022-01710-w

  • Cellular Senescence: Molecular Targets, Biomarkers, and Senolytic Drugs

    International Journal of Molecular Sciences · 2022 · 10.3390/ijms23084168

  • Human virus detection with graphene-based materials

    Biosensors and Bioelectronics · 2020 · 10.1016/j.bios.2020.112436

  • Disulfiram’s anti-cancer activity reflects targeting NPL4, not inhibition of aldehyde dehydrogenase

    Oncogene · 2019 · 10.1038/s41388-019-0915-2

  • Genetic Markers in Triple-Negative Breast Cancer

    Clinical Breast Cancer · 2018 · 10.1016/j.clbc.2018.07.023

  • Nucleosidic DNA demethylating epigenetic drugs – A comprehensive review from discovery to clinic

    Pharmacology & Therapeutics · 2018 · 10.1016/j.pharmthera.2018.02.006

  • Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4

    Nature · 2017 · https://doi.org/10.1038/nature25016

  • YAP regulates cell mechanics by controlling focal adhesion assembly

    Nature Communications · 2017 · https://doi.org/10.1038/ncomms15321

  • Multicentre validation of a microRNA-based assay for diagnosing indeterminate thyroid nodules utilising fine needle aspirate smears

    Journal of Clinical Pathology · 2016 · 10.1136/jclinpath-2016-204089

  • MEG3: a novel long noncoding potentially tumour-suppressing RNA in meningiomas

    Journal of Neuro-Oncology · 2013 · 10.1007/s11060-012-1038-6

  • Aurora kinase inhibitors: Progress towards the clinic

    Investigational New Drugs · 2012 · 10.1007/s10637-012-9798-6

  • MiR‐195, miR‐196b, miR‐181c, miR‐21 expression levels and O‐6‐methylguanine‐DNA methyltransferase methylation status are associated with clinical outcome in glioblastoma patients

    Cancer Science · 2011 · 10.1111/j.1349-7006.2011.02092.x

  • Mass Spectrometry-Based Analysis of Proteomic Changes in the Root Tips of Flooded Soybean Seedlings

    Journal of Proteome Research · 2011 · 10.1021/pr200701y

  • Systems Analysis of Seed Filling in Arabidopsis: Using General Linear Modeling to Assess Concordance of Transcript and Protein Expression

    PLANT PHYSIOLOGY · 2010 · 10.1104/pp.109.152413

  • Clinical Relevance of KRAS in Human Cancers

    BioMed Research International · 2010 · https://doi.org/10.1155/2010/150960

  • The Expression of Three Genes in Primary Non–Small Cell Lung Cancer Is Associated with Metastatic Spread to the Brain

    Clinical Cancer Research · 2009 · 10.1158/1078-0432.ccr-08-2124

  • In-Depth Investigation of the Soybean Seed-Filling Proteome and Comparison with a Parallel Study of Rapeseed

    PLANT PHYSIOLOGY · 2008 · 10.1104/pp.108.119222

  • Novel markers for differentiation of lobular and ductal invasive breast carcinomas by laser microdissection and microarray analysis

    BMC Cancer · 2007 · https://doi.org/10.1186/1471-2407-7-55

  • Proteomic Analysis of Seed Filling in Brassica napus. Developmental Characterization of Metabolic Isozymes Using High-Resolution Two-Dimensional Gel Electrophoresis

    PLANT PHYSIOLOGY · 2006 · 10.1104/pp.105.075390

  • Protein and lipid composition analysis of oil bodies from two Brassica napus cultivars

    PROTEOMICS · 2006 · https://doi.org/10.1002/pmic.200600020

  • Pharmacological activities of natural triterpenoids and their therapeutic implications

    Natural Product Reports · 2006 · https://doi.org/10.1039/b515312n

  • 4-Arylazo-3,5-diamino-1H-pyrazole CDK Inhibitors: SAR Study, Crystal Structure in Complex with CDK2, Selectivity, and Cellular Effects

    Journal of Medicinal Chemistry · 2006 · 10.1021/jm0605740

  • A Systematic Proteomic Study of Seed Filling in Soybean. Establishment of High-Resolution Two-Dimensional Reference Maps, Expression Profiles, and an Interactive Proteome Database

    PLANT PHYSIOLOGY · 2005 · 10.1104/pp.104.056614

  • Synthesis of A-Seco Derivatives of Betulinic Acid with Cytotoxic Activity

    Journal of Natural Products · 2004 · 10.1021/np049938m

  • High-resolution two-dimensional electrophoresis separation of proteins from metal-stressed rice (Oryza sativa L.) leaves: Drastic reductions/ fragmentation of ribulose-1,5-bisphosphate carboxylase/oxygenase and induction of stress-related proteins

    Electrophoresis · 2001 · 10.1002/1522-2683(200108)22:13<2824::aid-elps2824>3.0.co;2-c

Current projects

    No projects listed.