Vladimı́r Křen

Research interests

Publications

• The silymarin composition… and why does it matter???

  Food Research International · 2017 · 10.1016/j.foodres.2017.07.017

• European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)

  Redox Biology · 2017 · 10.1016/j.redox.2017.05.007

• Isoquercitrin: Pharmacology, toxicology, and metabolism

  Food and Chemical Toxicology · 2014 · 10.1016/j.fct.2014.03.018

• Chemistry of silybin

  Natural Product Reports · 2014 · 10.1039/c3np70122k

• Enzymatic Glycosylation of Small Molecules: Challenging Substrates Require Tailored Catalysts

  Chemistry - A European Journal · 2012 · 10.1002/chem.201103069

• β-N-Acetylhexosaminidase: What's in a name…?

  Biotechnology Advances · 2010 · 10.1016/j.biotechadv.2010.04.004

• Glycosidases: a key to tailored carbohydrates

  Trends in biotechnology · 2009 · 10.1016/j.tibtech.2008.12.003

• Sweet antibiotics – the role of glycosidic residues in antibiotic and antitumor activity and their randomization

  FEMS Microbiology Reviews · 2008 · 10.1111/j.1574-6976.2008.00124.x

• Integrated genomic approaches implicate osteoglycin (Ogn) in the regulation of left ventricular mass

  Nature Genetics · 2008 · 10.1038/ng.134

• Mechanism of the Antioxidant Action of Silybin and 2,3-Dehydrosilybin Flavonolignans: A Joint Experimental and Theoretical Study

  The Journal of Physical Chemistry A · 2008 · 10.1021/jp075814h

• Biodegradation potential of the genus Rhodococcus

  Environment International · 2008 · https://doi.org/10.1016/j.envint.2008.07.018

• Silybin and Silymarin - New and Emerging Applications in Medicine

  Current Medicinal Chemistry · 2007 · https://doi.org/10.2174/092986707779941159

• Heritability and Tissue Specificity of Expression Quantitative Trait Loci

  PLoS Genetics · 2006 · 10.1371/journal.pgen.0020172

• Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease

  Nature Genetics · 2005 · https://doi.org/10.1038/ng1522

• Oxidised derivatives of silybin and their antiradical and antioxidant activity

  Bioorganic & Medicinal Chemistry · 2004 · 10.1016/j.bmc.2004.07.064

• Glycosides in Medicine: “The Role of Glycosidic Residue in Biological Activity”

  Current Medicinal Chemistry · 2001 · https://doi.org/10.2174/0929867013372193

• Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats

  Nature Genetics · 1999 · https://doi.org/10.1038/5013

• Glycosylation employing bio-systems: from enzymes to whole cells

  Chemical Society Reviews · 1997 · 10.1039/cs9972600463

• Secondary metabolites of the fungusMonascus: A review

  Journal of Industrial Microbiology & Biotechnology · 1996 · 10.1007/bf01569999

• Mapping of quantitative trait loci for blood pressure and cardiac mass in the rat by genome scanning of recombinant inbred strains.

  Journal of Clinical Investigation · 1995 · 10.1172/jci118244

• A genetic linkage map of the laboratory rat, Rattus norvegicus

  Nature Genetics · 1995 · 10.1038/ng0195-63

Current projects

No projects listed.