Song Tan

Research interests

Publications

• Principles of nucleosome recognition by chromatin factors and enzymes

  Current Opinion in Structural Biology · 2021 · https://doi.org/10.1016/j.sbi.2021.05.006

• Nucleosome Structure and Function

  Chemical Reviews · 2014 · https://doi.org/10.1021/cr500373h

• Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome

  Nature · 2014 · https://doi.org/10.1038/nature13890

• Exchange of associated factors directs a switch in HBO1 acetyltransferase histone tail specificity

  Genes & Development · 2013 · https://doi.org/10.1101/gad.223396.113

• Structure of RCC1 chromatin factor bound to the nucleosome core particle

  Nature · 2010 · https://doi.org/10.1038/nature09321

• DNA Methylation Increases Nucleosome Compaction and Rigidity

  Journal of the American Chemical Society · 2010 · https://doi.org/10.1021/ja910264z

• Interplay of Chromatin Modifiers on a Short Basic Patch of Histone H4 Tail Defines the Boundary of Telomeric Heterochromatin

  Molecular Cell · 2007 · https://doi.org/10.1016/j.molcel.2007.12.002

• ING Tumor Suppressor Proteins Are Critical Regulators of Chromatin Acetylation Required for Genome Expression and Perpetuation

  Molecular Cell · 2006 · https://doi.org/10.1016/j.molcel.2005.12.007

• Comparison of affinity tags for protein purification

  Protein Expression and Purification · 2005 · https://doi.org/10.1016/j.pep.2005.01.019

• Krüppel-like Factor-6 Promotes Preadipocyte Differentiation through Histone Deacetylase 3-dependent Repression of DLK1

  Journal of Biological Chemistry · 2005 · https://doi.org/10.1074/jbc.m500463200

• The pST44 polycistronic expression system for producing protein complexes in Escherichia coli

  Protein Expression and Purification · 2005 · https://doi.org/10.1016/j.pep.2004.12.002

• Structural and Functional Conservation of the NuA4 Histone Acetyltransferase Complex from Yeast to Humans

  Molecular and Cellular Biology · 2004 · https://doi.org/10.1128/mcb.24.5.1884-1896.2004

• Yeast Enhancer of Polycomb defines global Esa1-dependent acetylation of chromatin

  Genes & Development · 2003 · https://doi.org/10.1101/gad.1056603

• Role of the Ada2 and Ada3 Transcriptional Coactivators in Histone Acetylation

  Journal of Biological Chemistry · 2002 · https://doi.org/10.1074/jbc.m110849200

• Essential Role for the SANT Domain in the Functioning of Multiple Chromatin Remodeling Enzymes

  Molecular Cell · 2002 · https://doi.org/10.1016/s1097-2765(02)00634-2

• Recruitment of HAT Complexes by Direct Activator Interactions with the ATM-Related Tra1 Subunit

  Science · 2001 · https://doi.org/10.1126/science.1060214

• A Modular Polycistronic Expression System for Overexpressing Protein Complexes in Escherichia coli

  Protein Expression and Purification · 2001 · https://doi.org/10.1006/prep.2000.1363

• Crystal structure of the yeast MATα2/MCM1/DNA ternary complex

  Nature · 1998 · https://doi.org/10.1038/35563

• Crystal structure of a yeast TFIIA/TBP/DNA complex

  Nature · 1996 · https://doi.org/10.1038/381127a0

• Structure of serum response factor core bound to DNA

  Nature · 1995 · https://doi.org/10.1038/376490a0

Current projects

No projects listed.