Jiří Litzman

Research interests

Publications

• Initial presenting manifestations in 16,486 patients with inborn errors of immunity include infections and noninfectious manifestations

  Journal of Allergy and Clinical Immunology · 2021 · 10.1016/j.jaci.2021.04.015

• Therapeutic options for CTLA-4 insufficiency

  Journal of Allergy and Clinical Immunology · 2021 · 10.1016/j.jaci.2021.04.039

• European Society for Immunodeficiencies (ESID) and European Reference Network on Rare Primary Immunodeficiency, Autoinflammatory and Autoimmune Diseases (ERN RITA) Complement Guideline: Deficiencies, Diagnosis, and Management

  Journal of Clinical Immunology · 2020 · 10.1007/s10875-020-00754-1

• CVID-Associated Tumors: Czech Nationwide Study Focused on Epidemiology, Immunology, and Genetic Background in a Cohort of Patients With CVID

  Frontiers in Immunology · 2019 · 10.3389/fimmu.2018.03135

• Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4–insufficient subjects

  Journal of Allergy and Clinical Immunology · 2018 · https://doi.org/10.1016/j.jaci.2018.02.055

• Infectious Complications and Immune/Inflammatory Response in Cardiogenic Shock Patients

  Shock · 2016 · 10.1097/shk.0000000000000756

• When to initiate immunoglobulin replacement therapy (IGRT) in antibody deficiency: a practical approach

  Clinical & Experimental Immunology · 2016 · 10.1111/cei.12915

• Long-term outcomes of 176 patients with X-linked hyper-IgM syndrome treated with or without hematopoietic cell transplantation

  Journal of Allergy and Clinical Immunology · 2016 · 10.1016/j.jaci.2016.07.039

• Common variants at PVT1, ATG13–AMBRA1, AHI1 and CLEC16A are associated with selective IgA deficiency

  Nature Genetics · 2016 · 10.1038/ng.3675

• Prognosis of Good syndrome: mortality and morbidity of thymoma associated immunodeficiency in perspective

  Clinical Immunology · 2016 · 10.1016/j.clim.2016.07.025

• Clinical picture and treatment of 2212 patients with common variable immunodeficiency

  Journal of Allergy and Clinical Immunology · 2014 · https://doi.org/10.1016/j.jaci.2013.12.1077

• New and recurrent gain-of-function STAT1 mutations in patients with chronic mucocutaneous candidiasis from Eastern and Central Europe

  Journal of Medical Genetics · 2013 · 10.1136/jmedgenet-2013-101570

• Outcomes of splenectomy in patients with common variable immunodeficiency (CVID): a survey of 45 patients

  Clinical & Experimental Immunology · 2012 · 10.1111/cei.12039

• Soluble BAFF Levels Inversely Correlate with Peripheral B Cell Numbers and the Expression of BAFF Receptors

  The Journal of Immunology · 2011 · 10.4049/jimmunol.1102321

• Mutations in STAT3 and diagnostic guidelines for hyper-IgE syndrome

  Journal of Allergy and Clinical Immunology · 2010 · 10.1016/j.jaci.2009.10.059

• Matrix metalloproteinase-9 and matrix metalloproteinase-2 as biomarkers of various courses in multiple sclerosis

  Multiple Sclerosis Journal · 2009 · 10.1177/1352458508099482

• Immunoglobulin D enhances immune surveillance by activating antimicrobial, proinflammatory and B cell–stimulating programs in basophils

  Nature Immunology · 2009 · 10.1038/ni.1748

• Reduced memory B cells in patients with hyper IgE syndrome

  Clinical Immunology · 2008 · 10.1016/j.clim.2008.08.002

• Gross Deletions Involving IGHM, BTK, or Artemis: A Model for Genomic Lesions Mediated by Transposable Elements

  The American Journal of Human Genetics · 2008 · 10.1016/j.ajhg.2007.10.011

• The EUROclass trial: defining subgroups in common variable immunodeficiency

  Blood · 2007 · 10.1182/blood-2007-06-091744

• Impaired Toll-like receptor 8–mediated IL-6 and TNF-α production in antigen-presenting cells from patients with X-linked agammaglobulinemia

  Blood · 2006 · 10.1182/blood-2006-07-037960

• ICOS deficiency in patients with common variable immunodeficiency

  Clinical Immunology · 2004 · 10.1016/j.clim.2004.07.002

• Clinical, immunologic and genetic analysis of 29 patients with autosomal recessive hyper-IgM syndrome due to Activation-Induced Cytidine Deaminase deficiency

  Clinical Immunology · 2003 · 10.1016/j.clim.2003.10.007

• Intravenous immunoglobulin, splenectomy, and antibiotic prophylaxis in Wiskott-Aldrich syndrome.

  Archives of Disease in Childhood · 1996 · 10.1136/adc.75.5.436

• A defect in the early phase of T-cell receptor-mediated T-cell activation in patients with common variable immunodeficiency

  Blood · 1994 · 10.1182/blood.v84.12.4234.bloodjournal84124234

Current projects

No projects listed.