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Karel Smetana

Researcher Next ID · RN-041830

Researcher · Biochemistry, Genetics and Molecular Biology

Charles University

Prague, Czechia

Accepting doctoral researchersFunding unknown
Works count
541
Citation count
9,809
H-index
48
i10-index
223

Research interests

Biochemistry, Genetics and Molecular Biology
Immunology and Microbiology
RNA modifications and cancer
Galectins and Cancer Biology
Glycosylation and Glycoproteins Research
RNA and protein synthesis mechanisms
RNA Research and Splicing

Publications

  • The Role of IL-6 in Cancer Cell Invasiveness and Metastasis—Overview and Therapeutic Opportunities

    Cells · 2022 · 10.3390/cells11223698

  • Molecular Changes Underlying Hypertrophic Scarring Following Burns Involve Specific Deregulations at All Wound Healing Stages (Inflammation, Proliferation and Maturation)

    International Journal of Molecular Sciences · 2021 · 10.3390/ijms22020897

  • Interleukin-6: Molecule in the Intersection of Cancer, Ageing and COVID-19

    International Journal of Molecular Sciences · 2020 · 10.3390/ijms21217937

  • Ageing as an Important Risk Factor for Cancer

    Anticancer Research · 2016 · 10.21873/anticanres.11069

  • Simultaneous blocking of IL-6 and IL-8 is sufficient to fully inhibit CAF-induced human melanoma cell invasiveness

    Histochemistry and Cell Biology · 2016 · 10.1007/s00418-016-1433-8

  • Melanoma cells influence the differentiation pattern of human epidermal keratinocytes

    Molecular Cancer · 2015 · https://doi.org/10.1186/1476-4598-14-1

  • A guide into glycosciences: How chemistry, biochemistry and biology cooperate to crack the sugar code

    Biochimica et Biophysica Acta (BBA) - General Subjects · 2014 · 10.1016/j.bbagen.2014.03.016

  • Upregulation of IL‐6, IL‐8 and CXCL‐1 production in dermal fibroblasts by normal/malignant epithelial cells in vitro: Immunohistochemical and transcriptomic analyses

    Biology of the Cell · 2012 · 10.1111/boc.201200018

  • Smooth muscle actin‐expressing stromal fibroblasts in head and neck squamous cell carcinoma: Increased expression of galectin‐1 and induction of poor prognosis factors

    International Journal of Cancer · 2012 · 10.1002/ijc.27550

  • The Miniature Pig as an Animal Model in Biomedical Research

    Annals of the New York Academy of Sciences · 2005 · https://doi.org/10.1196/annals.1334.015

  • New aspects of galectin functionality in nuclei of cultured bone marrow stromal and epidermal cells: biotinylated galectins as tool to detect specific binding sites

    Biology of the Cell · 2003 · 10.1016/j.biolcel.2003.08.002

  • Mitochondrial and endoplasmic reticulum stress-induced apoptotic pathways are activated by 5-aminolevulinic acid-based photodynamic therapy in HL60 leukemia cells

    Journal of Photochemistry and Photobiology B Biology · 2003 · 10.1016/s1011-1344(02)00410-4

  • New aspects of galectin functionality in nuclei of cultured bone marrow stromal and epidermal cells: biotinylated galectins as tool to detect specific binding sites

    Biology of the Cell · 2003 · 10.1016/j.biolcel.2003.08.002

  • Cell biology of hydrogels

    Biomaterials · 1993 · 10.1016/0142-9612(93)90203-e

  • The influence of hydrogel functional groups on cell behavior

    Journal of Biomedical Materials Research · 1990 · 10.1002/jbm.820240405

  • Evidence from studies on segregated nucleoli that nucleolar silver staining proteins C23 and B23 are in the fibrillar component

    Experimental Cell Research · 1980 · 10.1016/0014-4827(80)90434-6

  • Proteins C23 and B23 are the major nucleolar silver staining proteins

    Life Sciences · 1979 · 10.1016/0024-3205(79)90512-5

  • The Nucleolus and Nucleolar DNA

    Elsevier eBooks · 1974 · 10.1016/b978-0-12-147601-4.50010-5

  • Ultrastructural aspects of the ribonucleo-protein network in nuclei of walker tumor and rat liver

    Experimental Cell Research · 1967 · 10.1016/0014-4827(67)90409-0

  • A nuclear ribonucleoprotein network

    Experimental Cell Research · 1963 · 10.1016/0014-4827(63)90169-1

  • Quantitative Aspects of Isolation of Nucleoli of the Walker Carcinosarcoma and Liver of the Rat

    Cancer Research · 1963

  • The nucleolus of the cancer cell: a review.

    PubMed · 1963

Current projects

    No projects listed.