С. Б. Середенин

Research interests

Publications

• Chaperone Sigma1R and Antidepressant Effect

  International Journal of Molecular Sciences · 2020 · 10.3390/ijms21197088

• Low‐molecular mimetics of nerve growth factor and brain‐derived neurotrophic factor: Design and pharmacological properties

  Medicinal Research Reviews · 2020 · 10.1002/med.21721

• Mimetics of brain-derived neurotrophic factor loops 1 and 4 are active in a model of ischemic stroke in rats

  Drug Design Development and Therapy · 2016 · 10.2147/dddt.s118768

• Dimeric dipeptide mimetics of the nerve growth factor Loop 4 and Loop 1 activate TRKA with different patterns of intracellular signal transduction

  Journal of Biomedical Science · 2015 · 10.1186/s12929-015-0198-z

• Design, synthesis and anxiolytic-like activity of 1-arylpyrrolo[1,2-a]pyrazine-3-carboxamides

  Bioorganic & Medicinal Chemistry · 2015 · 10.1016/j.bmc.2015.04.049

• Antidepressant Effect of Dimeric Dipeptide GSB-106, an Original Low-Molecular-Weight Mimetic of BDNF

  Acta Naturae · 2013 · 10.32607/20758251-2013-5-4-105-109

• Original Nerve Growth Factor Mimetic Dipeptide GK-2 Restores Impaired Cognitive Functions in Rat Models of Alzheimer’s Disease

  Acta Naturae · 2013 · 10.32607/20758251-2013-5-3-84-91

• Stimulation of Sigma Receptors with Afobazole Blocks Activation of Microglia and Reduces Toxicity Caused by Amyloid-β25–35

  Journal of Pharmacology and Experimental Therapeutics · 2013 · 10.1124/jpet.113.208348

• Afobazole Activation of σ-1 Receptors Modulates Neuronal Responses to Amyloid-β25–35

  Journal of Pharmacology and Experimental Therapeutics · 2013 · 10.1124/jpet.113.208330

• Brain-derived neurotrophic factor loop 4 dipeptide mimetic GSB-106 activates TrkB, Erk, and Akt and promotes neuronal survival in vitro

  Doklady Biochemistry and Biophysics · 2013 · 10.1134/s1607672913040121

• Design and synthesis of dipeptide mimetics of the brain-derived neurotrophic factor

  Russian Journal of Bioorganic Chemistry · 2012 · 10.1134/s1068162012030053

• In Vitro Study of Neuroprotective Properties of GK-2, a New Original Nerve Growth Factor Mimetic

  Bulletin of Experimental Biology and Medicine · 2011 · 10.1007/s10517-011-1202-6

• Novel low-molecular-weight mimetics of the nerve growth factor

  Doklady Biochemistry and Biophysics · 2010 · 10.1134/s160767291005011x

• Evaluation of Genotoxicity and Reproductive Toxicity of Silicon Nanocrystals

  Bulletin of Experimental Biology and Medicine · 2010 · 10.1007/s10517-010-0967-3

• GVS‐111 prevents oxidative damage and apoptosis in normal and Down's syndrome human cortical neurons

  International Journal of Developmental Neuroscience · 2003 · 10.1016/s0736-5748(03)00031-5

• Anxiolytic Activity of Endogenous Nootropic Dipeptide Cycloprolylglycine in Elevated Plus-Maze Test

  Bulletin of Experimental Biology and Medicine · 2001 · 10.1023/a:1017928116025

• Memory restoring and neuroprotective effects of the proline-containing dipeptide, GVS-111, in a photochemical stroke model

  Behavioural Pharmacology · 1999 · 10.1097/00008877-199909000-00013

• Behavioral Similarities and Differences among Alcohol‐Preferring and ‐Nonpreferring Rats: Confirmation by Factor Analysis and Extension to Additional Groups

  Alcoholism Clinical and Experimental Research · 1997 · 10.1111/j.1530-0277.1997.tb03847.x

• Identification of a novel endogenous memory facilitating cyclic dipeptide cyclo‐prolylglycine in rat brain

  FEBS Letters · 1996 · 10.1016/0014-5793(96)00722-3

• To drink or not to drink: Open field behavior in alcohol-preferring and-nonpreferring rat strains

  Physiology & Behavior · 1995 · 10.1016/0031-9384(94)00299-k

• To drink or not to drink: Tests of anxiety and immobility in alcohol-preferring and alcohol-nonpreferring rat strains

  Physiology & Behavior · 1995 · 10.1016/0031-9384(94)00368-f

Current projects

No projects listed.