Marie Stiborová

Research interests

Publications

• DNA Adducts Formed by Aristolochic Acid Are Unique Biomarkers of Exposure and Explain the Initiation Phase of Upper Urothelial Cancer

  International Journal of Molecular Sciences · 2017 · 10.3390/ijms18102144

• Histone Deacetylase Inhibitors as Anticancer Drugs

  International Journal of Molecular Sciences · 2017 · https://doi.org/10.3390/ijms18071414

• Balkan endemic nephropathy: an update on its aetiology

  Archives of Toxicology · 2016 · 10.1007/s00204-016-1819-3

• The Role of Metallothionein in Oxidative Stress

  International Journal of Molecular Sciences · 2013 · https://doi.org/10.3390/ijms14036044

• Cisplatin-resistant prostate cancer model: Differences in antioxidant system, apoptosis and cell cycle

  International Journal of Oncology · 2013 · https://doi.org/10.3892/ijo.2013.2223

• Sarcosine as a Potential Prostate Cancer Biomarker—A Review

  International Journal of Molecular Sciences · 2013 · https://doi.org/10.3390/ijms140713893

• Exceptionally long-term persistence of DNA adducts formed by carcinogenic aristolochic acid I in renal tissue from patients with aristolochic acid nephropathy

  International Journal of Cancer · 2013 · 10.1002/ijc.28681

• The Epidemiology, Diagnosis, and Management of Aristolochic Acid Nephropathy

  Annals of Internal Medicine · 2013 · 10.7326/0003-4819-158-6-201303190-00006

• Mammalian metallothioneins: properties and functions

  Metallomics · 2012 · https://doi.org/10.1039/c2mt20081c

• Metallothioneins and zinc in cancer diagnosis and therapy

  Drug Metabolism Reviews · 2012 · https://doi.org/10.3109/03602532.2012.725414

• Modern Micro and Nanoparticle-Based Imaging Techniques

  Sensors · 2012 · https://doi.org/10.3390/s121114792

• Ellipticine cytotoxicity to cancer cell lines - a comparative study

  Interdisciplinary Toxicology · 2011 · https://doi.org/10.2478/v10102-011-0017-7

• Anthracyclines and ellipticines as DNA-damaging anticancer drugs: Recent advances

  Pharmacology & Therapeutics · 2011 · https://doi.org/10.1016/j.pharmthera.2011.07.006

• Vertebrate metallothioneins as target molecules for analytical techniques

  TrAC Trends in Analytical Chemistry · 2010 · https://doi.org/10.1016/j.trac.2010.02.004

• Mutagenicity and DNA adduct formation of PAH, nitro-PAH, and oxy-PAH fractions of atmospheric particulate matter from São Paulo, Brazil

  Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2008 · 10.1016/j.mrgentox.2007.12.007

• Metabolic activation of benzo[a]pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo: experiments with hepatic cytochrome P450 reductase null mice

  Carcinogenesis · 2007 · 10.1093/carcin/bgn002

• Metabolic activation of carcinogenic aristolochic acid, a risk factor for Balkan endemic nephropathy

  Mutation Research/Reviews in Mutation Research · 2007 · 10.1016/j.mrrev.2007.07.003

• Aristolochic acid mutagenesis: molecular clues to the aetiology of Balkan endemic nephropathy-associated urothelial cancer

  Carcinogenesis · 2007 · 10.1093/carcin/bgm082

• Evaluation of Isoflavone Aglycon and Glycoside Distribution in Soy Plants and Soybeans by Fast Column High-Performance Liquid Chromatography Coupled with a Diode-Array Detector

  Journal of Agricultural and Food Chemistry · 2005 · https://doi.org/10.1021/jf0502754

• Environmental Pollutant and Potent Mutagen 3-Nitrobenzanthrone Forms DNA Adducts after Reduction by NAD(P)H:Quinone Oxidoreductase and Conjugation by Acetyltransferases and Sulfotransferases in Human Hepatic Cytosols

  Cancer Research · 2005 · 10.1158/0008-5472.can-04-3544

• Human hepatic and renal microsomes, cytochromes P450 1A1/2, NADPH:Cytochrome P450 reductase and prostaglandin H synthase mediate the formation of aristolochic acid‐DNA adducts found in patients with urothelial cancer

  International Journal of Cancer · 2004 · 10.1002/ijc.20564

• The Anticancer Drug Ellipticine Forms Covalent DNA Adducts, Mediated by Human Cytochromes P450, through Metabolism to 13-Hydroxyellipticine and EllipticineN2-Oxide

  Cancer Research · 2004 · 10.1158/0008-5472.can-04-2202

• Expression of cytochrome P450 1A1 and its contribution to oxidation of a potential human carcinogen 1-phenylazo-2-naphthol (Sudan I) in human livers

  Cancer Letters · 2004 · 10.1016/j.canlet.2004.07.036

• Sanguinarine and chelerythrine: assessment of safety on pigs in ninety days feeding experiment

  Food and Chemical Toxicology · 2003 · 10.1016/j.fct.2003.08.007

• Human cytosolic enzymes involved in the metabolic activation of carcinogenic aristolochic acid: evidence for reductive activation by human NAD(P)H:quinone oxidoreductase

  Carcinogenesis · 2003 · 10.1093/carcin/bgg119

• Sudan I is a potential carcinogen for humans: evidence for its metabolic activation and detoxication by human recombinant cytochrome P450 1A1 and liver microsomes.

  PubMed · 2002

• Flavonoids-potent and versatile biologically active compounds interacting with cytochromes P450

  Chemico-Biological Interactions · 2002 · https://doi.org/10.1016/s0009-2797(01)00285-x

• Human Enzymes Involved in the Metabolic Activation of Carcinogenic Aristolochic Acids: Evidence for Reductive Activation by Cytochromes P450 1A1 and 1A2

  Chemical Research in Toxicology · 2001 · 10.1021/tx010059z

• The anticancer agent ellipticine on activation by cytochrome P450 forms covalent DNA adducts☆

  Biochemical Pharmacology · 2001 · 10.1016/s0006-2952(01)00806-1

• Effect of heavy metal ions on growth and biochemical characteristics of photosynthesis of barley and maize seedlings

  Biologia Plantarum · 1987 · 10.1007/bf02882221

Current projects

No projects listed.