Iris Barshack

Research interests

Publications

• Pan-cancer analyses reveal cancer-type-specific fungal ecologies and bacteriome interactions

  Cell · 2022 · https://doi.org/10.1016/j.cell.2022.09.005

• The human tumor microbiome is composed of tumor type–specific intracellular bacteria

  Science · 2020 · https://doi.org/10.1126/science.aay9189

• Cancer-associated fibroblast compositions change with breast cancer progression linking the ratio of S100A4+ and PDPN+ CAFs to clinical outcome

  Nature Cancer · 2020 · https://doi.org/10.1038/s43018-020-0082-y

• Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients

  Science · 2020 · https://doi.org/10.1126/science.abb5920

• Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence

  Cell · 2019 · https://doi.org/10.1016/j.cell.2019.08.012

• Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine

  Science · 2017 · https://doi.org/10.1126/science.aah5043

• Perioperative COX-2 and β-Adrenergic Blockade Improves Metastatic Biomarkers in Breast Cancer Patients in a Phase-II Randomized Trial

  Clinical Cancer Research · 2017 · https://doi.org/10.1158/1078-0432.ccr-17-0152

• Melanoma miRNA trafficking controls tumour primary niche formation

  Nature Cell Biology · 2016 · https://doi.org/10.1038/ncb3399

• MicroRNA-mediated loss of ADAR1 in metastatic melanoma promotes tumor growth

  Journal of Clinical Investigation · 2013 · https://doi.org/10.1172/jci62980

• Cancer Associated Fibroblasts express pro-inflammatory factors in human breast and ovarian tumors

  Biochemical and Biophysical Research Communications · 2013 · https://doi.org/10.1016/j.bbrc.2013.06.089

• Lack of interleukin-1α or interleukin-1β inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice

  Journal of Hepatology · 2011 · https://doi.org/10.1016/j.jhep.2011.01.048

• Effects of Hypoxia-Inducible Factor-1α Overexpression in Pregnant Mice

  American Journal Of Pathology · 2010 · https://doi.org/10.2353/ajpath.2010.090800

• MicroRNAs accurately identify cancer tissue origin

  Nature Biotechnology · 2008 · https://doi.org/10.1038/nbt1392

• MiR‐92b and miR‐9/9* Are Specifically Expressed in Brain Primary Tumors and Can Be Used to Differentiate Primary from Metastatic Brain Tumors

  Brain Pathology · 2008 · https://doi.org/10.1111/j.1750-3639.2008.00184.x

• Cell-replacement therapy for diabetes: Generating functional insulin-producing tissue from adult human liver cells

  Proceedings of the National Academy of Sciences · 2005 · https://doi.org/10.1073/pnas.0405277102

• Functional, Persistent, and Extended Liver to Pancreas Transdifferentiation

  Journal of Biological Chemistry · 2003 · https://doi.org/10.1074/jbc.m303127200

• Rhino‐Orbital and Rhino‐Orbito‐Cerebral Mucormycosis

  Otolaryngology · 2002 · https://doi.org/10.1067/mhn.2002.126587

• Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia

  Nature Medicine · 2000 · https://doi.org/10.1038/75050

• High susceptibility to bacterial infection, but no liver dysfunction, in mice compromised for hepatocyte NF-κB activation

  Nature Medicine · 2000 · https://doi.org/10.1038/75057

• Immunolocalization of β 2 -Glycoprotein I (Apolipoprotein H) to Human Atherosclerotic Plaques

  Circulation · 1999 · https://doi.org/10.1161/01.cir.99.17.2227

Current projects

No projects listed.