Christopher E. Barbieri

Research interests

Publications

• Identifying synergistic high-order 3D chromatin conformations from genome-scale nanopore concatemer sequencing

  Nature Biotechnology · 2022 · 10.1038/s41587-022-01289-z

• CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis

  Cancer Cell · 2019 · 10.1016/j.ccell.2019.03.001

• N-Myc–mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer

  Journal of Clinical Investigation · 2019 · https://doi.org/10.1172/jci127961

• FOXA1 mutations alter pioneering activity, differentiation and prostate cancer phenotypes

  Nature · 2019 · 10.1038/s41586-019-1318-9

• The long tail of oncogenic drivers in prostate cancer

  Nature Genetics · 2018 · https://doi.org/10.1038/s41588-018-0078-z

• Molecular Subtypes of Prostate Cancer

  Current Oncology Reports · 2018 · 10.1007/s11912-018-0707-9

• SPOP-Mutated/CHD1-Deleted Lethal Prostate Cancer and Abiraterone Sensitivity

  Clinical Cancer Research · 2018 · 10.1158/1078-0432.ccr-18-0937

• Prostate cancer–associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4

  Nature Medicine · 2017 · https://doi.org/10.1038/nm.4378

• The Role of Gut Microbiome in the Pathogenesis of Prostate Cancer: A Prospective, Pilot Study

  Urology · 2017 · 10.1016/j.urology.2017.08.039

• SPOP Mutation Drives Prostate Tumorigenesis In Vivo through Coordinate Regulation of PI3K/mTOR and AR Signaling

  Cancer Cell · 2017 · 10.1016/j.ccell.2017.02.004

• Clinical variability and molecular heterogeneity in prostate cancer

  Asian Journal of Andrology · 2016 · 10.4103/1008-682x.178852

• DNA Repair in Prostate Cancer: Biology and Clinical Implications

  European Urology · 2016 · 10.1016/j.eururo.2016.08.037

• The Molecular Taxonomy of Primary Prostate Cancer

  Cell · 2015 · https://doi.org/10.1016/j.cell.2015.10.025

• SPOP mutation leads to genomic instability in prostate cancer

  eLife · 2015 · 10.7554/elife.09207

• SPOP Mutations in Prostate Cancer across Demographically Diverse Patient Cohorts

  Neoplasia · 2014 · 10.1593/neo.131704

• Evidence for Molecular Differences in Prostate Cancer between African American and Caucasian Men

  Clinical Cancer Research · 2014 · 10.1158/1078-0432.ccr-13-2265

• Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover

  Proceedings of the National Academy of Sciences · 2013 · 10.1073/pnas.1304502110

• Punctuated Evolution of Prostate Cancer Genomes

  Cell · 2013 · https://doi.org/10.1016/j.cell.2013.03.021

• The Mutational Landscape of Prostate Cancer

  European Urology · 2013 · https://doi.org/10.1016/j.eururo.2013.05.029

• Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

  Zurich Open Repository and Archive (University of Zurich) · 2012 · https://doi.org/10.1038/ng.2279

• Association of Procedure Volume With Radical Cystectomy Outcomes in a Nationwide Database

  The Journal of Urology · 2007 · 10.1016/j.juro.2007.05.156

• p63 and epithelial biology

  Experimental Cell Research · 2006 · 10.1016/j.yexcr.2005.11.028

• Loss of p63 Leads to Increased Cell Migration and Up-regulation of Genes Involved in Invasion and Metastasis

  Cancer Research · 2006 · 10.1158/0008-5472.can-06-2020

Current projects

No projects listed.