Alicia Alonso

Research interests

Publications

• Epigenetic encoding, heritability and plasticity of glioma transcriptional cell states

  Nature Genetics · 2021 · https://doi.org/10.1038/s41588-021-00927-7

• Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

  Autophagy · 2021 · https://doi.org/10.1080/15548627.2020.1797280

• Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

  Autophagy · 2021 · https://doi.org/10.1080/15548627.2020.1797280

• Performance assessment of DNA sequencing platforms in the ABRF Next-Generation Sequencing Study

  Nature Biotechnology · 2021 · https://doi.org/10.1038/s41587-021-01049-5

• Circulating tumor DNA profile recognizes transformation to castration-resistant neuroendocrine prostate cancer

  Journal of Clinical Investigation · 2020 · https://doi.org/10.1172/jci131041

• Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia

  Nature · 2019 · https://doi.org/10.1038/s41586-019-1198-z

• Somatic mutations and cell identity linked by Genotyping of Transcriptomes

  Nature · 2019 · https://doi.org/10.1038/s41586-019-1367-0

• The Physical Properties of Ceramides in Membranes

  Annual Review of Biophysics · 2018 · https://doi.org/10.1146/annurev-biophys-070317-033309

• Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers

  Cancer Discovery · 2017 · https://doi.org/10.1158/2159-8290.cd-16-1032

• Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization

  Autophagy · 2016 · https://doi.org/10.1080/15548627.2016.1213927

• Detergent solubilization of lipid bilayers: a balance of driving forces

  Trends in Biochemical Sciences · 2013 · https://doi.org/10.1016/j.tibs.2012.11.005

• The octamer is the major form of CENP-A nucleosomes at human centromeres

  Nature Structural & Molecular Biology · 2013 · https://doi.org/10.1038/nsmb.2562

• Transbilayer (flip‐flop) lipid motion and lipid scrambling in membranes

  FEBS Letters · 2009 · https://doi.org/10.1016/j.febslet.2009.12.049

• Effects of ceramide and other simple sphingolipids on membrane lateral structure

  Biochimica et Biophysica Acta (BBA) - Biomembranes · 2008 · https://doi.org/10.1016/j.bbamem.2008.09.002

• Phase diagrams of lipid mixtures relevant to the study of membrane rafts

  Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 2008 · https://doi.org/10.1016/j.bbalip.2008.09.002

• Giant Unilamellar Vesicles Electroformed from Native Membranes and Organic Lipid Mixtures under Physiological Conditions

  Biophysical Journal · 2007 · https://doi.org/10.1529/biophysj.107.116228

• Biophysics of sphingolipids I. Membrane properties of sphingosine, ceramides and other simple sphingolipids

  Biochimica et Biophysica Acta (BBA) - Biomembranes · 2006 · https://doi.org/10.1016/j.bbamem.2006.09.011

• Detergent-Resistant, Ceramide-Enriched Domains in Sphingomyelin/Ceramide Bilayers

  Biophysical Journal · 2005 · https://doi.org/10.1529/biophysj.105.067710

• Sphingomyelinases: enzymology and membrane activity

  FEBS Letters · 2002 · https://doi.org/10.1016/s0014-5793(02)03482-8

• Membrane Restructuring via Ceramide Results in Enhanced Solute Efflux

  Journal of Biological Chemistry · 2002 · https://doi.org/10.1074/jbc.m111568200

• Interaction of Cholesterol with Sphingomyelin in Mixed Membranes Containing Phosphatidylcholine, Studied by Spin-Label ESR and IR Spectroscopies. A Possible Stabilization of Gel-Phase Sphingolipid Domains by Cholesterol

  Biochemistry · 2001 · https://doi.org/10.1021/bi0019803

• Compartmentalization of ceramide signaling: physical foundations and biological effects

  Journal of Cellular Physiology · 2000 · https://doi.org/10.1002/1097-4652(200009)184:3<285::aid-jcp2>3.0.co;2-3

• Structure and functional properties of diacylglycerols in membranes1This work is dedicated to Professor Vittorio Luzzati on occasion of his 75th birthday.1

  Progress in Lipid Research · 1999 · https://doi.org/10.1016/s0163-7827(98)00021-6

• Ceramides in Phospholipid Membranes: Effects on Bilayer Stability and Transition to Nonlamellar Phases

  Biophysical Journal · 1999 · https://doi.org/10.1016/s0006-3495(99)77201-2

• Different Effects of Enzyme-generated Ceramides and Diacylglycerols in Phospholipid Membrane Fusion and Leakage

  Journal of Biological Chemistry · 1996 · https://doi.org/10.1074/jbc.271.43.26616

• Intrinsic protein-lipid interactions

  Journal of Molecular Biology · 1982 · https://doi.org/10.1016/0022-2836(82)90501-0

Current projects

No projects listed.