Shai Izraeli

Research interests

Publications

• The KMT2A recombinome of acute leukemias in 2023

  Leukemia · 2023 · 10.1038/s41375-023-01877-1

• RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML

  Blood Advances · 2020 · 10.1182/bloodadvances.2019000901

• RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML

  Blood Advances · 2020 · 10.1182/bloodadvances.2019000901

• IKZF1 plus Defines a New Minimal Residual Disease–Dependent Very-Poor Prognostic Profile in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia

  Journal of Clinical Oncology · 2018 · 10.1200/jco.2017.74.3617

• The MLL recombinome of acute leukemias in 2017

  Leukemia · 2017 · https://doi.org/10.1038/leu.2017.213

• The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice

  Cancer Cell · 2016 · 10.1016/j.ccell.2016.03.008

• Childhood Acute Lymphoblastic Leukemia: Progress Through Collaboration

  Journal of Clinical Oncology · 2015 · https://doi.org/10.1200/jco.2014.59.1636

• The MLL recombinome of acute leukemias in 2013

  Leukemia · 2013 · https://doi.org/10.1038/leu.2013.135

• The landscape of somatic mutations in Down syndrome–related myeloid disorders

  Nature Genetics · 2013 · 10.1038/ng.2759

• Acute lymphoblastic leukemia in children with Down syndrome: a retrospective analysis from the Ponte di Legno study group

  Blood · 2013 · 10.1182/blood-2013-06-509463

• Intensive Chemotherapy for Childhood Acute Lymphoblastic Leukemia: Results of the Randomized Intercontinental Trial ALL IC-BFM 2002

  Journal of Clinical Oncology · 2013 · 10.1200/jco.2013.48.6522

• MiR-125 in normal and malignant hematopoiesis

  Leukemia · 2012 · 10.1038/leu.2012.90

• Identification of Regulators of Polyploidization Presents Therapeutic Targets for Treatment of AMKL

  Cell · 2012 · 10.1016/j.cell.2012.06.032

• Identification of Regulators of Polyploidization Presents Therapeutic Targets for Treatment of AMKL

  Cell · 2012 · 10.1016/j.cell.2012.06.032

• STIL is required for centriole duplication in human cells

  Journal of Cell Science · 2012 · 10.1242/jcs.104109

• Gain-of-function mutations in interleukin-7 receptor-α ( IL7R ) in childhood acute lymphoblastic leukemias

  The Journal of Experimental Medicine · 2011 · 10.1084/jem.20110580

• Presence of the P2RY8-CRLF2 rearrangement is associated with a poor prognosis in non–high-risk precursor B-cell acute lymphoblastic leukemia in children treated according to the ALL-BFM 2000 protocol

  Blood · 2010 · 10.1182/blood-2009-11-256131

• Insights into the manifestations, outcomes, and mechanisms of leukemogenesis in Down syndrome

  Blood · 2009 · 10.1182/blood-2008-11-163501

• Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group

  Blood · 2009 · https://doi.org/10.1182/blood-2009-08-235408

• Diagnostic Assay Based on hsa-miR-205 Expression Distinguishes Squamous From Nonsquamous Non–Small-Cell Lung Carcinoma

  Journal of Clinical Oncology · 2009 · 10.1200/jco.2008.19.4134

• New insights to the MLL recombinome of acute leukemias

  Leukemia · 2009 · https://doi.org/10.1038/leu.2009.33

• The Expression of Three Genes in Primary Non–Small Cell Lung Cancer Is Associated with Metastatic Spread to the Brain

  Clinical Cancer Research · 2009 · https://doi.org/10.1158/1078-0432.ccr-08-2124

• Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome

  The Lancet · 2008 · https://doi.org/10.1016/s0140-6736(08)61341-0

• Cytogenetic features of acute lymphoblastic and myeloid leukemias in pediatric patients with Down syndrome: an iBFM-SG study

  Blood · 2007 · 10.1182/blood-2007-09-114231

• Cytogenetic features of acute lymphoblastic and myeloid leukemias in pediatric patients with Down syndrome: an iBFM-SG study

  Blood · 2007 · 10.1182/blood-2007-09-114231

• The SIL gene is required for mouse embryonic axial development and left–right specification

  Nature · 1999 · 10.1038/21429

• The SIL gene is required for mouse embryonic axial development and left–right specification

  Nature · 1999 · 10.1038/21429

Current projects

No projects listed.