Cem Meydan

Research interests

Publications

• Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts

  Science Translational Medicine · 2023 · 10.1126/scitranslmed.abq1533

• Role of miR-2392 in driving SARS-CoV-2 infection

  Cell Reports · 2021 · 10.1016/j.celrep.2021.109839

• The spatial landscape of lung pathology during COVID-19 progression

  Nature · 2021 · 10.1038/s41586-021-03475-6

• A global metagenomic map of urban microbiomes and antimicrobial resistance

  Cell · 2021 · 10.1016/j.cell.2021.05.002

• Chemotherapy Induces Senescence-Like Resilient Cells Capable of Initiating AML Recurrence

  Cancer Discovery · 2021 · 10.1158/2159-8290.cd-20-1375

• Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions

  Nature Communications · 2021 · 10.1038/s41467-021-21361-7

• A diagnostic host response biosignature for COVID-19 from RNA profiling of nasal swabs and blood

  Science Advances · 2021 · 10.1126/sciadv.abe5984

• Long-term spaceflight and the cardiovascular system

  Precision Clinical Medicine · 2020 · 10.1093/pcmedi/pbaa022

• Immune complement and coagulation dysfunction in adverse outcomes of SARS-CoV-2 infection

  Nature Medicine · 2020 · 10.1038/s41591-020-1021-2

• Telomere Length Dynamics and DNA Damage Responses Associated with Long-Duration Spaceflight

  Cell Reports · 2020 · 10.1016/j.celrep.2020.108457

• Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact

  Cell · 2020 · 10.1016/j.cell.2020.11.002

• H1 histones control the epigenetic landscape by local chromatin compaction

  Nature · 2020 · 10.1038/s41586-020-3032-z

• Fundamental Biological Features of Spaceflight: Advancing the Field to Enable Deep-Space Exploration

  Cell · 2020 · 10.1016/j.cell.2020.10.050

• Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response

  Cancer Cell · 2020 · 10.1016/j.ccell.2020.04.004

• Long non-coding RNAs discriminate the stages and gene regulatory states of human humoral immune response

  Nature Communications · 2019 · 10.1038/s41467-019-08679-z

• The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight

  Science · 2019 · https://doi.org/10.1126/science.aau8650

• ketu mutant mice uncover an essential meiotic function for the ancient RNA helicase YTHDC2

  eLife · 2018 · 10.7554/elife.30919

• Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells

  Nature Genetics · 2017 · 10.1038/ng.3854

• Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers

  Cancer Discovery · 2017 · 10.1158/2159-8290.cd-16-1032

• Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in IDH2 - and TET2 -Mutant Acute Myeloid Leukemia

  Cancer Discovery · 2017 · 10.1158/2159-8290.cd-16-1049

• CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas

  Cancer Discovery · 2016 · 10.1158/2159-8290.cd-16-0975

• Mutational Cooperativity Linked to Combinatorial Epigenetic Gain of Function in Acute Myeloid Leukemia

  Cancer Cell · 2015 · 10.1016/j.ccell.2015.03.009

• Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome

  Nature Methods · 2015 · 10.1038/nmeth.3453

• Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis

  The Journal of Experimental Medicine · 2015 · 10.1084/jem.20151317

• Geospatial Resolution of Human and Bacterial Diversity with City-Scale Metagenomics

  Cell Systems · 2015 · 10.1016/j.cels.2015.01.001

Current projects

No projects listed.