Michal Harel

Research interests

Publications

• Hippocampal sharp-wave ripples linked to visual episodic recollection in humans

  Science · 2019 · 10.1126/science.aax1030

• Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence

  Cell · 2019 · https://doi.org/10.1016/j.cell.2019.08.012

• A unifying principle underlying the extracellular field potential spectral responses in the human cortex

  Journal of Neurophysiology · 2015 · 10.1152/jn.00943.2014

• Acetylcholinesterase: From 3D structure to function

  Chemico-Biological Interactions · 2010 · 10.1016/j.cbi.2010.01.042

• Neural “Ignition”: Enhanced Activation Linked to Perceptual Awareness in Human Ventral Stream Visual Cortex

  Neuron · 2009 · 10.1016/j.neuron.2009.11.001

• Internally Generated Reactivation of Single Neurons in Human Hippocampus During Free Recall

  Science · 2008 · 10.1126/science.1164685

• Interhemispheric correlations of slow spontaneous neuronal fluctuations revealed in human sensory cortex

  Nature Neuroscience · 2008 · 10.1038/nn.2177

• When the Brain Loses Its Self: Prefrontal Inactivation during Sensorimotor Processing

  Neuron · 2006 · 10.1016/j.neuron.2006.03.015

• Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes

  Nature Structural & Molecular Biology · 2004 · 10.1038/nsmb767

• X‐ray structure of human acid‐β‐glucosidase, the defective enzyme in Gaucher disease

  EMBO Reports · 2003 · 10.1038/sj.embor.embor873

• Contrast Sensitivity in Human Visual Areas and Its Relationship to Object Recognition

  Journal of Neurophysiology · 2002 · 10.1152/jn.2002.87.6.3102

• Kinetic and Structural Studies on the Interaction of Cholinesterases with the Anti-Alzheimer Drug Rivastigmine ,

  Biochemistry · 2002 · 10.1021/bi020016x

• Three‐dimensional structures of Drosophila melanogaster acetylcholinesterase and of its complexes with two potent inhibitors

  Protein Science · 2000 · 10.1110/ps.9.6.1063

• Specific chemical and structural damage to proteins produced by synchrotron radiation

  Proceedings of the National Academy of Sciences · 2000 · 10.1073/pnas.97.2.623

• Structures of recombinant native and E202Q mutant human acetylcholinesterase complexed with the snake-venom toxin fasciculin-II

  Acta Crystallographica Section D Biological Crystallography · 2000 · 10.1107/s0907444900010659

• Crystal Structures of Aged Phosphonylated Acetylcholinesterase: Nerve Agent Reaction Products at the Atomic Level,

  Biochemistry · 1999 · 10.1021/bi982678l

• Structure of acetylcholinesterase complexed with the nootropic alkaloid, (–)-huperzine A

  Nature Structural & Molecular Biology · 1997 · 10.1038/nsb0197-57

• The X-ray Structure of a Transition State Analog Complex Reveals the Molecular Origins of the Catalytic Power and Substrate Specificity of Acetylcholinesterase

  Journal of the American Chemical Society · 1996 · 10.1021/ja952232h

• Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase.

  Proceedings of the National Academy of Sciences · 1993 · 10.1073/pnas.90.19.9031

• Relationship between intrinsic connections and functional architecture revealed by optical imaging and in vivo targeted biocytin injections in primate striate cortex.

  Proceedings of the National Academy of Sciences · 1993 · 10.1073/pnas.90.22.10469

• Relationship between sequence conservation and three‐dimensional structure in a large family of esterases, lipases, and related proteins

  Protein Science · 1993 · 10.1002/pro.5560020309

• Cortical hierarchy reflected in the organization of intrinsic connections in macaque monkey visual cortex

  The Journal of Comparative Neurology · 1993 · 10.1002/cne.903340103

• The α / β hydrolase fold

  Protein Engineering Design and Selection · 1992 · 10.1093/protein/5.3.197

• Conversion of acetylcholinesterase to butyrylcholinesterase: modeling and mutagenesis.

  Proceedings of the National Academy of Sciences · 1992 · 10.1073/pnas.89.22.10827

• Atomic Structure of Acetylcholinesterase from Torpedo californica : A Prototypic Acetylcholine-Binding Protein

  Science · 1991 · 10.1126/science.1678899

Current projects

No projects listed.