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Stéphanie Lheureux

Researcher Next ID · RN-042597

Researcher · Biochemistry, Genetics and Molecular Biology

University of Toronto

Toronto, New Zealand

Accepting doctoral researchersFunding unknown
Works count
519
Citation count
8,301
H-index
38
i10-index
98

Research interests

Biochemistry, Genetics and Molecular Biology
Medicine
Ovarian cancer diagnosis and treatment
PARP inhibition in cancer therapy
Cancer Genomics and Diagnostics
Cancer Immunotherapy and Biomarkers
Endometrial and Cervical Cancer Treatments

Publications

  • First-Line Lenvatinib Plus Pembrolizumab Versus Chemotherapy for Advanced Endometrial Cancer: A Randomized, Open-Label, Phase III Trial

    Journal of Clinical Oncology · 2024 · 10.1200/jco-24-01326

  • First-Line Lenvatinib Plus Pembrolizumab Versus Chemotherapy for Advanced Endometrial Cancer: A Randomized, Open-Label, Phase III Trial

    Journal of Clinical Oncology · 2024 · 10.1200/jco-24-01326

  • Clinical Validation of Human Papilloma Virus Circulating Tumor DNA for Early Detection of Residual Disease After Chemoradiation in Cervical Cancer

    Journal of Clinical Oncology · 2023 · 10.1200/jco.23.00954

  • MASCC multidisciplinary evidence-based recommendations for the management of malignant bowel obstruction in advanced cancer

    Supportive Care in Cancer · 2022 · 10.1007/s00520-022-06889-8

  • Translational randomized phase II trial of cabozantinib in combination with nivolumab in advanced, recurrent, or metastatic endometrial cancer

    Journal for ImmunoTherapy of Cancer · 2022 · 10.1136/jitc-2021-004233

  • Molecular, cellular and systemic aspects of epithelial ovarian cancer and its tumor microenvironment

    Seminars in Cancer Biology · 2022 · https://doi.org/10.1016/j.semcancer.2022.03.027

  • ATARI trial: ATR inhibitor in combination with olaparib in gynecological cancers with ARID1A loss or no loss (ENGOT/GYN1/NCRI)

    International Journal of Gynecological Cancer · 2021 · 10.1136/ijgc-2021-002973

  • Pan-cancer analysis of longitudinal metastatic tumors reveals genomic alterations and immune landscape dynamics associated with pembrolizumab sensitivity

    Nature Communications · 2021 · 10.1038/s41467-021-25432-7

  • Phase II Trial of Symptom Screening With Targeted Early Palliative Care for Patients With Advanced Cancer

    Journal of the National Comprehensive Cancer Network · 2021 · 10.6004/jnccn.2020.7803

  • Personalized circulating tumor DNA analysis as a predictive biomarker in solid tumor patients treated with pembrolizumab

    Nature Cancer · 2020 · https://doi.org/10.1038/s43018-020-0096-5

  • PARP Inhibitors in the Management of Ovarian Cancer: ASCO Guideline

    Journal of Clinical Oncology · 2020 · https://doi.org/10.1200/jco.20.01924

  • An open-label, phase II multicohort study of an oral hypomethylating agent CC-486 and durvalumab in advanced solid tumors

    Journal for ImmunoTherapy of Cancer · 2020 · 10.1136/jitc-2020-000883

  • FIGO 2018 stage IB2 (2–4 cm) Cervical cancer treated with Neo-adjuvant chemotherapy followed by fertility Sparing Surgery (CONTESSA); Neo-Adjuvant Chemotherapy and Conservative Surgery in Cervical Cancer to Preserve Fertility (NEOCON-F). A PMHC, DGOG, GCIG/CCRN and multicenter study

    International Journal of Gynecological Cancer · 2019 · 10.1136/ijgc-2019-000398

  • Epithelial ovarian cancer: Evolution of management in the era of precision medicine

    CA A Cancer Journal for Clinicians · 2019 · https://doi.org/10.3322/caac.21559

  • Epithelial ovarian cancer

    The Lancet · 2019 · https://doi.org/10.1016/s0140-6736(18)32552-2

  • A Clinical and Molecular Phase II Trial of Oral ENMD-2076 in Ovarian Clear Cell Carcinoma (OCCC): A Study of the Princess Margaret Phase II Consortium

    Clinical Cancer Research · 2018 · 10.1158/1078-0432.ccr-18-1244

  • Landscape of genomic alterations in high-grade serous ovarian cancer from exceptional long- and short-term survivors

    Genome Medicine · 2018 · 10.1186/s13073-018-0590-x

  • Traceback: A Proposed Framework to Increase Identification and Genetic Counseling of BRCA1 and BRCA2 Mutation Carriers Through Family-Based Outreach

    Journal of Clinical Oncology · 2017 · 10.1200/jco.2016.70.3439

  • Molecularly targeted therapies in cancer: a guide for the nuclear medicine physician

    European Journal of Nuclear Medicine and Molecular Imaging · 2017 · 10.1007/s00259-017-3695-3

  • Towards a new standardized method for circulating miRNAs profiling in clinical studies: Interest of the exogenous normalization to improve miRNA signature accuracy

    Molecular Oncology · 2016 · 10.1016/j.molonc.2016.03.005

  • Treatment strategies for endometrial cancer: current practice and perspective

    Current Opinion in Obstetrics & Gynecology · 2016 · https://doi.org/10.1097/gco.0000000000000338

  • A phase 2 study of cediranib in recurrent or persistent ovarian, peritoneal or fallopian tube cancer: A trial of the Princess Margaret, Chicago and California Phase II Consortia

    Gynecologic Oncology · 2015 · 10.1016/j.ygyno.2015.04.009

  • F18-Choline, a Novel PET Tracer for Parathyroid Adenoma?

    The Journal of Clinical Endocrinology & Metabolism · 2013 · 10.1210/jc.2013-2084

  • Nanocarriers for the targeted treatment of ovarian cancers

    Biomaterials · 2012 · 10.1016/j.biomaterials.2012.10.055

Current projects

    No projects listed.