Tom Wilkinson

Research interests

Publications

• Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults

  Nature Medicine · 2022 · https://doi.org/10.1038/s41591-022-01780-9

• Safety and efficacy of inhaled nebulised interferon beta-1a (SNG001) for treatment of SARS-CoV-2 infection: a randomised, double-blind, placebo-controlled, phase 2 trial

  The Lancet Respiratory Medicine · 2020 · https://doi.org/10.1016/s2213-2600(20)30511-7

• Inflammatory Endotype–associated Airway Microbiome in Chronic Obstructive Pulmonary Disease Clinical Stability and Exacerbations: A Multicohort Longitudinal Analysis

  American Journal of Respiratory and Critical Care Medicine · 2020 · https://doi.org/10.1164/rccm.202009-3448oc

• Longitudinal profiling of the lung microbiome in the AERIS study demonstrates repeatability of bacterial and eosinophilic COPD exacerbations

  Thorax · 2018 · https://doi.org/10.1136/thoraxjnl-2017-210408

• British Thoracic Society guidelines for home oxygen use in adults: accredited by NICE

  Thorax · 2015 · https://doi.org/10.1136/thoraxjnl-2015-206865

• Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans

  Nature Medicine · 2012 · https://doi.org/10.1038/nm.2612

• A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virus

  Proceedings of the National Academy of Sciences · 2010 · https://doi.org/10.1073/pnas.0912186107

• Viral Load Drives Disease in Humans Experimentally Infected with Respiratory Syncytial Virus

  American Journal of Respiratory and Critical Care Medicine · 2010 · https://doi.org/10.1164/rccm.201002-0221oc

• Long-term Erythromycin Therapy Is Associated with Decreased Chronic Obstructive Pulmonary Disease Exacerbations

  American Journal of Respiratory and Critical Care Medicine · 2008 · https://doi.org/10.1164/rccm.200801-145oc

• Inflammatory changes, recovery and recurrence at COPD exacerbation

  European Respiratory Journal · 2006 · https://doi.org/10.1183/09031936.00092506

• Use of Plasma Biomarkers at Exacerbation of Chronic Obstructive Pulmonary Disease

  American Journal of Respiratory and Critical Care Medicine · 2006 · https://doi.org/10.1164/rccm.200604-506oc

• Effect of Interactions Between Lower Airway Bacterial and Rhinoviral Infection in Exacerbations of COPD

  CHEST Journal · 2006 · https://doi.org/10.1378/chest.129.2.317

• Systemic and Upper and Lower Airway Inflammation at Exacerbation of Chronic Obstructive Pulmonary Disease

  American Journal of Respiratory and Critical Care Medicine · 2005 · https://doi.org/10.1164/rccm.200505-704oc

• Bronchiectasis, Exacerbation Indices, and Inflammation in Chronic Obstructive Pulmonary Disease

  American Journal of Respiratory and Critical Care Medicine · 2004 · https://doi.org/10.1164/rccm.200305-648oc

• Exacerbations and Time Spent Outdoors in Chronic Obstructive Pulmonary Disease

  American Journal of Respiratory and Critical Care Medicine · 2004 · https://doi.org/10.1164/rccm.200408-1054oc

• Early Therapy Improves Outcomes of Exacerbations of Chronic Obstructive Pulmonary Disease

  American Journal of Respiratory and Critical Care Medicine · 2004 · https://doi.org/10.1164/rccm.200310-1443oc

• Airway Bacterial Load and FEV1 Decline in Patients with Chronic Obstructive Pulmonary Disease

  American Journal of Respiratory and Critical Care Medicine · 2003 · https://doi.org/10.1164/rccm.200210-1179oc

Current projects

No projects listed.