Kangdong Liu

Research interests

Publications

• Unraveling the complexity of STAT3 in cancer: molecular understanding and drug discovery

  Journal of Experimental & Clinical Cancer Research · 2024 · https://doi.org/10.1186/s13046-024-02949-5

• Protein translation: biological processes and therapeutic strategies for human diseases

  Signal Transduction and Targeted Therapy · 2024 · https://doi.org/10.1038/s41392-024-01749-9

• Integrins in cancer: Emerging mechanisms and therapeutic opportunities

  Pharmacology & Therapeutics · 2023 · https://doi.org/10.1016/j.pharmthera.2023.108458

• Erianin suppresses constitutive activation of MAPK signaling pathway by inhibition of CRAF and MEK1/2

  Signal Transduction and Targeted Therapy · 2023 · https://doi.org/10.1038/s41392-023-01329-3

• The Role of p21-Activated Kinases in Cancer and Beyond: Where Are We Heading?

  Frontiers in Cell and Developmental Biology · 2021 · 10.3389/fcell.2021.641381

• The Role of p21-Activated Kinases in Cancer and Beyond: Where Are We Heading?

  Frontiers in Cell and Developmental Biology · 2021 · 10.3389/fcell.2021.641381

• Targeting AURKA in Cancer: molecular mechanisms and opportunities for Cancer therapy

  Molecular Cancer · 2021 · https://doi.org/10.1186/s12943-020-01305-3

• The Role of p21-Activated Kinases in Cancer and Beyond: Where Are We Heading?

  Frontiers in Cell and Developmental Biology · 2021 · 10.3389/fcell.2021.641381

• CDK12 and PAK2 as novel therapeutic targets for human gastric cancer

  Theranostics · 2020 · 10.7150/thno.46137

• Targeting CDK12 for Cancer Therapy: Function, Mechanism, and Drug Discovery

  Cancer Research · 2020 · https://doi.org/10.1158/0008-5472.can-20-2245

• CDK12 and PAK2 as novel therapeutic targets for human gastric cancer

  Theranostics · 2020 · 10.7150/thno.46137

• CDK12 and PAK2 as novel therapeutic targets for human gastric cancer

  Theranostics · 2020 · 10.7150/thno.46137

• Knockdown of Pyruvate Kinase M Inhibits Cell Growth and Migration by Reducing NF-kB Activity in Triple-Negative Breast Cancer Cells.

  PubMed · 2019 · 10.14348/molcells.2019.0038

• Knockdown of Pyruvate Kinase M Inhibits Cell Growth and Migration by Reducing NF-kB Activity in Triple-Negative Breast Cancer Cells.

  PubMed · 2019 · 10.14348/molcells.2019.0038

• Knockdown of Pyruvate Kinase M Inhibits Cell Growth and Migration by Reducing NF-kB Activity in Triple-Negative Breast Cancer Cells.

  PubMed · 2019 · 10.14348/molcells.2019.0038

• Targeting AKT with Oridonin Inhibits Growth of Esophageal Squamous Cell Carcinoma In Vitro and Patient-Derived Xenografts In Vivo

  Molecular Cancer Therapeutics · 2018 · 10.1158/1535-7163.mct-17-0823

• Targeting AKT with Oridonin Inhibits Growth of Esophageal Squamous Cell Carcinoma In Vitro and Patient-Derived Xenografts In Vivo

  Molecular Cancer Therapeutics · 2018 · 10.1158/1535-7163.mct-17-0823

• Targeting AKT with Oridonin Inhibits Growth of Esophageal Squamous Cell Carcinoma In Vitro and Patient-Derived Xenografts In Vivo

  Molecular Cancer Therapeutics · 2018 · 10.1158/1535-7163.mct-17-0823

• Phosphorylation of Caspase-7 by p21-activated Protein Kinase (PAK) 2 Inhibits Chemotherapeutic Drug-induced Apoptosis of Breast Cancer Cell Lines

  Journal of Biological Chemistry · 2011 · 10.1074/jbc.m111.236596

• Phosphorylation of Caspase-7 by p21-activated Protein Kinase (PAK) 2 Inhibits Chemotherapeutic Drug-induced Apoptosis of Breast Cancer Cell Lines

  Journal of Biological Chemistry · 2011 · 10.1074/jbc.m111.236596

• SHAFTS: A Hybrid Approach for 3D Molecular Similarity Calculation. 2. Prospective Case Study in the Discovery of Diverse p90 Ribosomal S6 Protein Kinase 2 Inhibitors To Suppress Cell Migration

  Journal of Medicinal Chemistry · 2011 · 10.1021/jm200139j

• SHAFTS: A Hybrid Approach for 3D Molecular Similarity Calculation. 2. Prospective Case Study in the Discovery of Diverse p90 Ribosomal S6 Protein Kinase 2 Inhibitors To Suppress Cell Migration

  Journal of Medicinal Chemistry · 2011 · 10.1021/jm200139j

• SHAFTS: A Hybrid Approach for 3D Molecular Similarity Calculation. 2. Prospective Case Study in the Discovery of Diverse p90 Ribosomal S6 Protein Kinase 2 Inhibitors To Suppress Cell Migration

  Journal of Medicinal Chemistry · 2011 · 10.1021/jm200139j

• Phosphorylation of Caspase-7 by p21-activated Protein Kinase (PAK) 2 Inhibits Chemotherapeutic Drug-induced Apoptosis of Breast Cancer Cell Lines

  Journal of Biological Chemistry · 2011 · 10.1074/jbc.m111.236596

Current projects

No projects listed.