Richard H. Furneaux

Research interests

Publications

• Azetidine Based Transition State Analogue Inhibitors of N-Ribosyl Hydrolases and Phosphorylases

  Journal of Medicinal Chemistry · 2008 · https://doi.org/10.1021/jm701265n

• Structure and Antiviral Activity of the Galactofucan Sulfates Extracted from Undaria Pinnatifida (Phaeophyta)

  Journal of Applied Phycology · 2006 · https://doi.org/10.1007/s10811-006-9096-9

• Femtomolar Transition State Analogue Inhibitors of 5′-Methylthioadenosine/S-Adenosylhomocysteine Nucleosidase from Escherichia coli

  Journal of Biological Chemistry · 2005 · https://doi.org/10.1074/jbc.m414472200

• Targeting a Novel Plasmodium falciparum Purine Recycling Pathway with Specific Immucillins

  Journal of Biological Chemistry · 2004 · https://doi.org/10.1074/jbc.m412693200

• Plasmodium falciparum Purine Nucleoside Phosphorylase

  Journal of Biological Chemistry · 2004 · https://doi.org/10.1074/jbc.c400068200

• Achieving the Ultimate Physiological Goal in Transition State Analogue Inhibitors for Purine Nucleoside Phosphorylase

  Journal of Biological Chemistry · 2003 · https://doi.org/10.1074/jbc.c300259200

• Synthesis of Second-Generation Transition State Analogues of Human Purine Nucleoside Phosphorylase

  Journal of Medicinal Chemistry · 2003 · https://doi.org/10.1021/jm030305z

• Transition State Analogue Inhibitors of Purine Nucleoside Phosphorylase from Plasmodium falciparum

  Journal of Biological Chemistry · 2002 · https://doi.org/10.1074/jbc.m105905200

• Purine-less Death in Plasmodium falciparumInduced by Immucillin-H, a Transition State Analogue of Purine Nucleoside Phosphorylase

  Journal of Biological Chemistry · 2002 · https://doi.org/10.1074/jbc.m105906200

• Immucillin H, a powerful transition-state analog inhibitor of purine nucleoside phosphorylase, selectively inhibits human T lymphocytes

  Proceedings of the National Academy of Sciences · 2001 · https://doi.org/10.1073/pnas.071050798

• Addition of Lithiated 9-Deazapurine Derivatives to a Carbohydrate Cyclic Imine: Convergent Synthesis of the Aza-C-nucleoside Immucillins

  The Journal of Organic Chemistry · 2001 · https://doi.org/10.1021/jo0155613

• Transition State Structure of Purine Nucleoside Phosphorylase and Principles of Atomic Motion in Enzymatic Catalysis,

  Biochemistry · 2000 · https://doi.org/10.1021/bi002499f

• Transition-state analogs as inhibitors of human and malarial hypoxanthine-guanine phosphoribosyltransferases.

  Nature Structural Biology · 1999 · https://doi.org/10.1038/9367

• The 2.0 Å Structure of Malarial Purine Phosphoribosyltransferase in Complex with a Transition-State Analogue Inhibitor ,

  Biochemistry · 1999 · https://doi.org/10.1021/bi990664p

• The 2.0 A structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor.

  Nature Structural Biology · 1999 · https://doi.org/10.1038/9376

• One-Third-the-Sites Transition-State Inhibitors for Purine Nucleoside Phosphorylase

  Biochemistry · 1998 · https://doi.org/10.1021/bi980658d

• Chemical methods for the analysis of sulphated galactans from red algae

  Carbohydrate Research · 1991 · https://doi.org/10.1016/0008-6215(91)80129-b

• Some reactions of levoglucosenone

  Carbohydrate Research · 1979 · https://doi.org/10.1016/s0008-6215(00)86069-3

• Production of levoglucosan and glucose from pyrolysis of cellulosic materials

  Journal of Applied Polymer Science · 1979 · https://doi.org/10.1002/app.1979.070231209

Current projects

No projects listed.