Yuqin Chen

Research interests

Publications

• Smart Liposomal Nanocarrier Enhanced the Treatment of Ischemic Stroke through Neutrophil Extracellular Traps and Cyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase-Stimulator of Interferon Genes (cGAS-STING) Pathway Inhibition of Ischemic Penumbra

  ACS Nano · 2023 · 10.1021/acsnano.3c03390

• Upregulation of mechanosensitive channel Piezo1 involved in high shear stress-induced pulmonary hypertension

  Thrombosis Research · 2022 · 10.1016/j.thromres.2022.08.006

• Up-regulating lncRNA OIP5-AS1 protects neuron injury against cerebral hypoxia-ischemia induced inflammation and oxidative stress in microglia/macrophage through activating CTRP3 via sponging miR-186-5p

  International Immunopharmacology · 2021 · 10.1016/j.intimp.2020.107339

• Upregulation of Piezo1 (Piezo Type Mechanosensitive Ion Channel Component 1) Enhances the Intracellular Free Calcium in Pulmonary Arterial Smooth Muscle Cells From Idiopathic Pulmonary Arterial Hypertension Patients

  Hypertension · 2021 · 10.1161/hypertensionaha.120.16629

• Metformin inhibits MAPK signaling and rescues pancreatic aquaporin 7 expression to induce insulin secretion in type 2 diabetes mellitus

  Journal of Biological Chemistry · 2021 · 10.1016/j.jbc.2021.101002

• Efficacy and safety of Bufei Huoxue capsules in the management of convalescent patients with COVID-19 infection: A multicentre, double-blind, and randomised controlled trial

  Journal of Ethnopharmacology · 2021 · 10.1016/j.jep.2021.114830

• Tetramethylpyrazine: A promising drug for the treatment of pulmonary hypertension

  British Journal of Pharmacology · 2020 · 10.1111/bph.15000

• Dysregulation of BMP9/BMPR2/SMAD signalling pathway contributes to pulmonary fibrosis and pulmonary hypertension induced by bleomycin in rats

  British Journal of Pharmacology · 2020 · 10.1111/bph.15285

• Altered Airway Microbiota Composition in Patients With Pulmonary Hypertension

  Hypertension · 2020 · 10.1161/hypertensionaha.120.15025

• Mitomycin C induces pulmonary vascular endothelial‐to‐mesenchymal transition and pulmonary veno‐occlusive disease via Smad3‐dependent pathway in rats

  British Journal of Pharmacology · 2020 · 10.1111/bph.15314

• Activation of DR3 signaling causes loss of ILC3s and exacerbates intestinal inflammation

  Nature Communications · 2019 · 10.1038/s41467-019-11304-8

• Sodium Tanshinone IIA Sulfonate Decreases Cigarette Smoke-Induced Inflammation and Oxidative Stress via Blocking the Activation of MAPK/HIF-1α Signaling Pathway

  Frontiers in Pharmacology · 2018 · 10.3389/fphar.2018.00263

• Divergent changes of p53 in pulmonary arterial endothelial and smooth muscle cells involved in the development of pulmonary hypertension

  American Journal of Physiology-Lung Cellular and Molecular Physiology · 2018 · 10.1152/ajplung.00538.2017

• Arabidopsis HSP70‐16 is required for flower opening under normal or mild heat stress temperatures

  Plant Cell & Environment · 2018 · 10.1111/pce.13480

• Epigenetic restriction of Hippo signaling by MORC2 underlies stemness of hepatocellular carcinoma cells

  Cell Death and Differentiation · 2018 · 10.1038/s41418-018-0095-6

• Fecal Microbiota Transplantation Ameliorates Experimentally Induced Colitis in Mice by Upregulating AhR

  Frontiers in Microbiology · 2018 · 10.3389/fmicb.2018.01921

• Comparison and evaluation of two different methods to establish the cigarette smoke exposure mouse model of COPD

  Scientific Reports · 2017 · 10.1038/s41598-017-15685-y

• Involvements of p38 MAPK and oxidative stress in the ozone-induced enhancement of AHR and pulmonary inflammation in an allergic asthma model

  Respiratory Research · 2017 · 10.1186/s12931-017-0697-4

• MicroRNA-223 Attenuates Hypoxia-induced Vascular Remodeling by Targeting RhoB/MLC2 in Pulmonary Arterial Smooth Muscle Cells

  Scientific Reports · 2016 · 10.1038/srep24900

• Sodium tanshinone IIA sulfonate inhibits hypoxia-induced enhancement of SOCE in pulmonary arterial smooth muscle cells via the PKG-PPAR-γ signaling axis

  American Journal of Physiology-Cell Physiology · 2016 · 10.1152/ajpcell.00252.2015

• Metformin suppresses hypoxia-induced stabilization of HIF-1α through reprogramming of oxygen metabolism in hepatocellular carcinoma

  Oncotarget · 2015 · 10.18632/oncotarget.6418

• Hypoxia inducible factor-1-dependent up-regulation of BMP4 mediates hypoxia-induced increase of TRPC expression in PASMCs

  Cardiovascular Research · 2015 · 10.1093/cvr/cvv122

• Sodium Tanshinone IIA Sulfonate Inhibits Canonical Transient Receptor Potential Expression in Pulmonary Arterial Smooth Muscle from Pulmonary Hypertensive Rats

  American Journal of Respiratory Cell and Molecular Biology · 2013 · 10.1165/rcmb.2012-0071oc

• Effects of chronic exposure to cigarette smoke on canonical transient receptor potential expression in rat pulmonary arterial smooth muscle

  American Journal of Physiology-Cell Physiology · 2013 · 10.1152/ajpcell.00048.2013

• Expression of store-operated Ca2+entry and transient receptor potential canonical and vanilloid-related proteins in rat distal pulmonary venous smooth muscle

  American Journal of Physiology-Lung Cellular and Molecular Physiology · 2010 · 10.1152/ajplung.00176.2009

Current projects

No projects listed.