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Richard D. Williams

Researcher Next ID · RN-042856

Researcher · Biochemistry, Genetics and Molecular Biology

Clinical Trials New Zealand

Hamilton, New Zealand

Accepting doctoral researchersFunding unknown
Works count
328
Citation count
10,967
H-index
56
i10-index
160

Research interests

Biochemistry, Genetics and Molecular Biology
Medicine
Neuroscience
Renal and related cancers
Prostate Cancer Treatment and Research
Neuroscience and Neuropharmacology Research
Bladder and Urothelial Cancer Treatments
Renal cell carcinoma treatment

Publications

  • Cathepsin S (CTSS) activity in health and disease - A treasure trove of untapped clinical potential

    Molecular Aspects of Medicine · 2022 · 10.1016/j.mam.2022.101106

  • Cathepsin S (CTSS) activity in health and disease - A treasure trove of untapped clinical potential

    Molecular Aspects of Medicine · 2022 · 10.1016/j.mam.2022.101106

  • Cathepsin S (CTSS) activity in health and disease - A treasure trove of untapped clinical potential

    Molecular Aspects of Medicine · 2022 · 10.1016/j.mam.2022.101106

  • Mutations in the SIX1/2 Pathway and the DROSHA/DGCR8 miRNA Microprocessor Complex Underlie High-Risk Blastemal Type Wilms Tumors

    Cancer Cell · 2015 · https://doi.org/10.1016/j.ccell.2015.01.002

  • Cathepsin S: therapeutic, diagnostic, and prognostic potential

    Biological Chemistry · 2015 · https://doi.org/10.1515/hsz-2015-0114

  • Discovery of Novel Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5 Reveals Chemical and Functional Diversity and In Vivo Activity in Rat Behavioral Models of Anxiolytic and Antipsychotic Activity

    Molecular Pharmacology · 2010 · 10.1124/mol.110.067207

  • Discovery of Novel Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5 Reveals Chemical and Functional Diversity and In Vivo Activity in Rat Behavioral Models of Anxiolytic and Antipsychotic Activity

    Molecular Pharmacology · 2010 · 10.1124/mol.110.067207

  • Discovery and Evaluation of BMS-708163, a Potent, Selective and Orally Bioavailable γ-Secretase Inhibitor

    ACS Medicinal Chemistry Letters · 2010 · https://doi.org/10.1021/ml1000239

  • Discovery of Novel Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5 Reveals Chemical and Functional Diversity and In Vivo Activity in Rat Behavioral Models of Anxiolytic and Antipsychotic Activity

    Molecular Pharmacology · 2010 · 10.1124/mol.110.067207

  • mGluR5 Positive Allosteric Modulators Facilitate both Hippocampal LTP and LTD and Enhance Spatial Learning

    Neuropsychopharmacology · 2009 · https://doi.org/10.1038/npp.2009.30

  • Comparison of Echocardiographic and Cardiac Magnetic Resonance Imaging Measurements of Functional Single Ventricular Volumes, Mass, and Ejection Fraction (from the Pediatric Heart Network Fontan Cross-Sectional Study)††A list of participating institutions and investigators appears in the Appendix.

    The American Journal of Cardiology · 2009 · https://doi.org/10.1016/j.amjcard.2009.03.058

  • Discovery, Characterization, and Antiparkinsonian Effect of Novel Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4

    Molecular Pharmacology · 2008 · https://doi.org/10.1124/mol.108.049551

  • An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmission

    Nature Chemical Biology · 2007 · 10.1038/nchembio.2007.55

  • An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmission

    Nature Chemical Biology · 2007 · 10.1038/nchembio.2007.55

  • An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmission

    Nature Chemical Biology · 2007 · 10.1038/nchembio.2007.55

  • Colorectal adenoma to carcinoma progression follows multiple pathways of chromosomal instability

    Gastroenterology · 2002 · 10.1053/gast.2002.36051

  • Rate Acceleration of the Baylis−Hillman Reaction in Polar Solvents (Water and Formamide). Dominant Role of Hydrogen Bonding, Not Hydrophobic Effects, Is Implicated

    The Journal of Organic Chemistry · 2001 · https://doi.org/10.1021/jo016073y

  • Adenoviral-Mediated Transfer of the TNF-Related Apoptosis-Inducing Ligand/Apo-2 Ligand Gene Induces Tumor Cell Apoptosis

    The Journal of Immunology · 2000 · https://doi.org/10.4049/jimmunol.165.5.2886

  • ( 111 ) INDIUM-CAPROMAB PENDETIDE IN THE EVALUATION OF PATIENTS WITH RESIDUAL OR RECURRENT PROSTATE CANCER AFTER RADICAL PROSTATECTOMY

    The Journal of Urology · 1998 · 10.1016/s0022-5347(01)63239-7

  • ( 111 ) INDIUM-CAPROMAB PENDETIDE IN THE EVALUATION OF PATIENTS WITH RESIDUAL OR RECURRENT PROSTATE CANCER AFTER RADICAL PROSTATECTOMY

    The Journal of Urology · 1998 · 10.1016/s0022-5347(01)63239-7

  • ( 111 ) INDIUM-CAPROMAB PENDETIDE IN THE EVALUATION OF PATIENTS WITH RESIDUAL OR RECURRENT PROSTATE CANCER AFTER RADICAL PROSTATECTOMY

    The Journal of Urology · 1998 · 10.1016/s0022-5347(01)63239-7

  • Treatment of Renal Cell Carcinoma in Von Hippel-Lindau Disease: A Multicenter Study

    The Journal of Urology · 1995 · 10.1016/s0022-5347(01)67318-x

  • Treatment of Renal Cell Carcinoma in Von Hippel-Lindau Disease: A Multicenter Study

    The Journal of Urology · 1995 · 10.1016/s0022-5347(01)67318-x

  • Treatment of Renal Cell Carcinoma in Von Hippel-Lindau Disease: A Multicenter Study

    The Journal of Urology · 1995 · 10.1016/s0022-5347(01)67318-x

  • Synthesis of messenger RNAs for transforming growth factors alpha and beta and the epidermal growth factor receptor by human tumors.

    PubMed · 1987

  • Human transforming growth factor-alpha stimulates bone resorption in vitro.

    Journal of Clinical Investigation · 1985 · 10.1172/jci112202

  • Human transforming growth factor-alpha stimulates bone resorption in vitro.

    Journal of Clinical Investigation · 1985 · 10.1172/jci112202

  • Human transforming growth factor-alpha stimulates bone resorption in vitro.

    Journal of Clinical Investigation · 1985 · 10.1172/jci112202

  • Human renal carcinoma cells produce hypercalcemia in the nude mouse and a novel protein recognized by parathyroid hormone receptors.

    Journal of Clinical Investigation · 1983 · 10.1172/jci110825

  • Human renal carcinoma cells produce hypercalcemia in the nude mouse and a novel protein recognized by parathyroid hormone receptors.

    Journal of Clinical Investigation · 1983 · 10.1172/jci110825

  • Human renal carcinoma cells produce hypercalcemia in the nude mouse and a novel protein recognized by parathyroid hormone receptors.

    Journal of Clinical Investigation · 1983 · 10.1172/jci110825

  • Incidental Carcinoma of the Prostate: a Review of the Literature and Critical Reappraisal of Classification

    The Journal of Urology · 1980 · https://doi.org/10.1016/s0022-5347(17)55589-5

Current projects

    No projects listed.