Matthew D. Dun

Research interests

Publications

• Intracerebroventricular B7-H3-targeting CAR T cells for diffuse intrinsic pontine glioma: a phase 1 trial

  Nature Medicine · 2025 · 10.1038/s41591-024-03451-3

• Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways

  Cancer Discovery · 2023 · 10.1158/2159-8290.cd-23-0131

• Imipridones affect tumor bioenergetics and promote cell lineage differentiation in diffuse midline gliomas

  Neuro-Oncology · 2022 · 10.1093/neuonc/noac041

• Intraventricular B7-H3 CAR T Cells for Diffuse Intrinsic Pontine Glioma: Preliminary First-in-Human Bioactivity and Safety

  Cancer Discovery · 2022 · https://doi.org/10.1158/2159-8290.cd-22-0750

• The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location

  Nature Genetics · 2022 · https://doi.org/10.1038/s41588-022-01236-3

• Imipridones affect tumor bioenergetics and promote cell lineage differentiation in diffuse midline gliomas

  Neuro-Oncology · 2022 · 10.1093/neuonc/noac041

• The Role of Reactive Oxygen Species in Acute Myeloid Leukaemia

  International Journal of Molecular Sciences · 2019 · 10.3390/ijms20236003

• Mechanisms of tethering and cargo transfer during epididymosome-sperm interactions

  BMC Biology · 2019 · 10.1186/s12915-019-0653-5

• The Role of Reactive Oxygen Species in Acute Myeloid Leukaemia

  International Journal of Molecular Sciences · 2019 · 10.3390/ijms20236003

• Proteomic Profiling of Mouse Epididymosomes Reveals their Contributions to Post-testicular Sperm Maturation

  Molecular & Cellular Proteomics · 2018 · https://doi.org/10.1074/mcp.ra118.000946

• Characteristics of the Epididymal Luminal Environment Responsible for Sperm Maturation and Storage

  Frontiers in Endocrinology · 2018 · https://doi.org/10.3389/fendo.2018.00059

• Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons

  Nucleic Acids Research · 2014 · https://doi.org/10.1093/nar/gku594

• The presence of a truncated base excision repair pathway in human spermatozoa, Mediated by OGG1

  Journal of Cell Science · 2013 · 10.1242/jcs.121657

• The role of molecular chaperones in spermatogenesis and the post-testicular maturation of mammalian spermatozoa

  Human Reproduction Update · 2012 · 10.1093/humupd/dms009

• The role of molecular chaperones in spermatogenesis and the post-testicular maturation of mammalian spermatozoa

  Human Reproduction Update · 2012 · 10.1093/humupd/dms009

• Involvement of multimeric protein complexes in mediating the capacitation-dependent binding of human spermatozoa to homologous zonae pellucidae

  Developmental Biology · 2011 · 10.1016/j.ydbio.2011.05.674

• The Chaperonin Containing TCP1 Complex (CCT/TRiC) Is Involved in Mediating Sperm-Oocyte Interaction

  Journal of Biological Chemistry · 2011 · 10.1074/jbc.m110.188888

• The Chaperonin Containing TCP1 Complex (CCT/TRiC) Is Involved in Mediating Sperm-Oocyte Interaction

  Journal of Biological Chemistry · 2011 · 10.1074/jbc.m110.188888

• Involvement of multimeric protein complexes in mediating the capacitation-dependent binding of human spermatozoa to homologous zonae pellucidae

  Developmental Biology · 2011 · 10.1016/j.ydbio.2011.05.674

Current projects

No projects listed.