Lance Richard McMahon

Research interests

Publications

• Activity of Mitragyna speciosa (“Kratom”) Alkaloids at Serotonin Receptors

  Journal of Medicinal Chemistry · 2021 · 10.1021/acs.jmedchem.1c00726

• Exploring the Chemistry of Alkaloids from Malaysian Mitragyna speciosa (Kratom) and the Role of Oxindoles on Human Opioid Receptors

  Journal of Natural Products · 2021 · 10.1021/acs.jnatprod.0c01055

• Metabolism of a Kratom Alkaloid Metabolite in Human Plasma Increases Its Opioid Potency and Efficacy

  ACS Pharmacology & Translational Science · 2020 · 10.1021/acsptsci.0c00075

• Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats

  Journal of Pharmacology and Experimental Therapeutics · 2020 · 10.1124/jpet.120.000189

• Investigation of the Adrenergic and Opioid Binding Affinities, Metabolic Stability, Plasma Protein Binding Properties, and Functional Effects of Selected Indole-Based Kratom Alkaloids

  Journal of Medicinal Chemistry · 2019 · 10.1021/acs.jmedchem.9b01465

• Exploration of cytochrome P450 inhibition mediated drug-drug interaction potential of kratom alkaloids

  Toxicology Letters · 2019 · 10.1016/j.toxlet.2019.11.005

• Kratom policy: The challenge of balancing therapeutic potential with public safety

  International Journal of Drug Policy · 2019 · 10.1016/j.drugpo.2019.05.003

• The effects of mitragynine and morphine on schedule-controlled responding and antinociception in rats

  Psychopharmacology · 2019 · 10.1007/s00213-019-05247-7

• Full Fatty Acid Amide Hydrolase Inhibition Combined with Partial Monoacylglycerol Lipase Inhibition: Augmented and Sustained Antinociceptive Effects with Reduced Cannabimimetic Side Effects in Mice

  Journal of Pharmacology and Experimental Therapeutics · 2015 · 10.1124/jpet.115.222851

• Purity of Synthetic Cannabinoids Sold Online for Recreational Use

  Journal of Analytical Toxicology · 2012 · 10.1093/jat/bkr018

• Acetaminophen differentially enhances social behavior and cortical cannabinoid levels in inbred mice

  Progress in Neuro-Psychopharmacology and Biological Psychiatry · 2012 · 10.1016/j.pnpbp.2012.04.011

• JWH-018 and JWH-073: Δ9-Tetrahydrocannabinol-Like Discriminative Stimulus Effects in Monkeys

  Journal of Pharmacology and Experimental Therapeutics · 2011 · 10.1124/jpet.111.187757

• Contingency Management

  Journal · 2010 · 10.1007/978-3-540-68706-1_929

• Conditioned Reinforcement

  Journal · 2010 · 10.1007/978-3-540-68706-1_4146

• Conditioned Reinforcement

  Journal · 2010 · 10.1007/978-3-540-68706-1_4146

• Clinical Global Impression Scales

  Journal · 2010 · 10.1007/978-3-540-68706-1_1422

• Clinical Global Impression Scales

  Journal · 2010 · 10.1007/978-3-540-68706-1_1422

• Clinical Global Impression Scales

  Journal · 2010 · 10.1007/978-3-540-68706-1_1422

• Contingency Management

  Journal · 2010 · 10.1007/978-3-540-68706-1_929

• Contingency Management

  Journal · 2010 · 10.1007/978-3-540-68706-1_929

• Circumventricular Organs

  Journal · 2010 · 10.1007/978-3-540-68706-1_1096

• Circumventricular Organs

  Journal · 2010 · 10.1007/978-3-540-68706-1_1096

• Circumventricular Organs

  Journal · 2010 · 10.1007/978-3-540-68706-1_1096

• Brain Stimulation Reward

  Journal · 2010 · 10.1007/978-3-540-68706-1_1309

• Memorial Delirium Assessment Scale

  Journal · 2010 · 10.1007/978-3-540-68706-1_1159

• Cognitive Neuroscience

  Journal · 2010 · 10.1007/978-3-540-68706-1_1345

• Cognitive Neuroscience

  Journal · 2010 · 10.1007/978-3-540-68706-1_1345

• Cognitive Neuroscience

  Journal · 2010 · 10.1007/978-3-540-68706-1_1345

• Controlled Clinical Trials

  Journal · 2010 · 10.1007/978-3-540-68706-1_3171

• Controlled Clinical Trials

  Journal · 2010 · 10.1007/978-3-540-68706-1_3171

• Controlled Clinical Trials

  Journal · 2010 · 10.1007/978-3-540-68706-1_3171

• Controlled Substances Act

  Journal · 2010 · 10.1007/978-3-540-68706-1_939

• Controlled Substances Act

  Journal · 2010 · 10.1007/978-3-540-68706-1_939

• Controlled Substances Act

  Journal · 2010 · 10.1007/978-3-540-68706-1_939

• Controlled Clinical Trial

  Journal · 2010 · 10.1007/978-3-540-68706-1_4149

• Controlled Clinical Trial

  Journal · 2010 · 10.1007/978-3-540-68706-1_4149

• Controlled Clinical Trial

  Journal · 2010 · 10.1007/978-3-540-68706-1_4149

• Cognitive Behavioral Therapy

  Journal · 2010 · 10.1007/978-3-540-68706-1_1429

• Cognitive Behavioral Therapy

  Journal · 2010 · 10.1007/978-3-540-68706-1_1429

• Cognitive Behavioral Therapy

  Journal · 2010 · 10.1007/978-3-540-68706-1_1429

• Conditioned Reinforcement

  Journal · 2010 · 10.1007/978-3-540-68706-1_4146

• Conditioned Reinforcement

  Journal · 2010 · 10.1007/978-3-540-68706-1_4146

• Conditioned Reinforcement

  Journal · 2010 · 10.1007/978-3-540-68706-1_4146

• Controlled Substances Act

  Journal · 2010 · 10.1007/978-3-540-68706-1_939

• Controlled Substances Act

  Journal · 2010 · 10.1007/978-3-540-68706-1_939

• Controlled Substances Act

  Journal · 2010 · 10.1007/978-3-540-68706-1_939

• Cognitive Behavioral Therapy

  Journal · 2010 · 10.1007/978-3-540-68706-1_1429

• Cognitive Behavioral Therapy

  Journal · 2010 · 10.1007/978-3-540-68706-1_1429

• Cognitive Behavioral Therapy

  Journal · 2010 · 10.1007/978-3-540-68706-1_1429

• Conditioned Reinforcement

  Journal · 2010 · 10.1007/978-3-540-68706-1_4146

• Interactions between Δ9-tetrahydrocannabinol and μ opioid receptor agonists in rhesus monkeys: discrimination and antinociception

  Psychopharmacology · 2008 · 10.1007/s00213-008-1157-0

• Differences in the relative potency of SR 141716A and AM 251 as antagonists of various in vivo effects of cannabinoid agonists in C57BL/6J mice

  European Journal of Pharmacology · 2007 · 10.1016/j.ejphar.2007.04.054

• Selective serotonin reuptake inhibitors enhance cocaine-induced locomotor activity and dopamine release in the nucleus accumbens

  Neuropharmacology · 2003 · 10.1016/s0028-3908(02)00381-7

• Differential Regulation of the Mesoaccumbens Circuit by Serotonin 5-Hydroxytryptamine (5-HT)2Aand 5-HT2CReceptors

  Journal of Neuroscience · 2001 · 10.1523/jneurosci.21-19-07781.2001

• Antagonism of 5-Hydroxytryptamine2A Receptors Attenuates the Behavioral Effects of Cocaine in Rats

  Journal of Pharmacology and Experimental Therapeutics · 2001 · 10.1016/s0022-3565(24)29546-x

• PVN infusion of GLP-1-(7—36) amide suppresses feeding but does not induce aversion or alter locomotion in rats

  American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 1998 · 10.1152/ajpregu.1998.274.1.r23

• Modulation of feeding by hypothalamic paraventricular nucleus α1- and α2-adrenergic receptors

  Life Sciences · 1993 · 10.1016/0024-3205(93)90243-v

Current projects

No projects listed.