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Lodewyk J. Mienie

Researcher Next ID · RN-043016

Researcher · Biochemistry, Genetics and Molecular Biology

North-West University

Potchefstroom, South Africa

Accepting doctoral researchersFunding unknown
Works count
1,053
Citation count
1,594
H-index
22
i10-index
48

Research interests

Biochemistry, Genetics and Molecular Biology
Medicine
Metabolism and Genetic Disorders
Glycogen Storage Diseases and Myoclonus
Corneal surgery and disorders
Diet and metabolism studies
Neurological and metabolic disorders

Publications

  • The GC–MS metabolomics signature in patients with fibromyalgia syndrome directs to dysbiosis as an aspect contributing factor of FMS pathophysiology

    Metabolomics · 2019 · 10.1007/s11306-019-1513-6

  • Uncovering the metabolic response of abalone (Haliotis midae) to environmental hypoxia through metabolomics

    Metabolomics · 2018 · 10.1007/s11306-018-1346-8

  • Characterising the metabolic differences related to growth variation in farmed Haliotis midae

    Aquaculture · 2018 · 10.1016/j.aquaculture.2018.04.052

  • GC–MS-based urinary organic acid profiling reveals multiple dysregulated metabolic pathways following experimental acute alcohol consumption

    Scientific Reports · 2018 · 10.1038/s41598-018-24128-1

  • The altered human serum metabolome induced by a marathon

    Metabolomics · 2018 · 10.1007/s11306-018-1447-4

  • The cross-tissue metabolic response of abalone (Haliotis midae) to functional hypoxia

    Biology Open · 2018 · 10.1242/bio.031070

  • The 1H-NMR-based metabolite profile of acute alcohol consumption: A metabolomics intervention study

    PLoS ONE · 2018 · 10.1371/journal.pone.0196850

  • Contribution towards a Metabolite Profile of the Detoxification of Benzoic Acid through Glycine Conjugation: An Intervention Study

    PLoS ONE · 2016 · 10.1371/journal.pone.0167309

  • A hypothetical astrocyte–microglia lactate shuttle derived from a 1H NMR metabolomics analysis of cerebrospinal fluid from a cohort of South African children with tuberculous meningitis

    Metabolomics · 2014 · 10.1007/s11306-014-0741-z

  • Inhibition of N-acetylglutamate synthase by various monocarboxylic and dicarboxylic short-chain coenzyme A esters and the production of alternative glutamate esters

    Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2013 · 10.1016/j.bbadis.2013.04.027

  • Disclosure of a putative biosignature for respiratory chain disorders through a metabolomics approach

    Metabolomics · 2012 · 10.1007/s11306-012-0455-z

  • Clinical variability of isovaleric acidemia in a genetically homogeneous population

    Journal of Inherited Metabolic Disease · 2012 · 10.1007/s10545-012-9457-2

  • Metabolomics of urinary organic acids in respiratory chain deficiencies in children

    Metabolomics · 2011 · 10.1007/s11306-011-0309-0

  • An overview of a cohort of South African patients with mitochondrial disorders

    Journal of Inherited Metabolic Disease · 2010 · 10.1007/s10545-009-9031-8

  • Ceramide Trihexosidase Deficiency

    Journal · 2009 · 10.1007/978-3-540-29676-8_8477

  • Glucose-6-Phosphate Dehydrogenase Deficiency

    Journal · 2009 · 10.1007/978-3-540-29676-8_709

  • Glycogen Storage Disease Type III

    Journal · 2009 · 10.1007/978-3-540-29676-8_8632

  • Congenital Hypothyroidism

    Journal · 2009 · 10.1007/978-3-540-29676-8_9114

  • Corticobasal Ganglionic Degeneration

    Journal · 2009 · 10.1007/978-3-540-29676-8_8232

  • Identification of 19 New Metabolites Induced by Abnormal Amino Acid Conjugation in Isovaleric Acidemia

    Clinical Chemistry · 2005 · 10.1373/clinchem.2005.048421

  • Melatonin prevents the free radical and MADD metabolic profiles induced by antituberculosis drugs in an animal model

    Journal of Pineal Research · 2004 · 10.1111/j.1600-079x.2004.00176.x

  • Acetyl-L-carnitine prevents total body hydroxyl free radical and uric acid production induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the rat

    Life Sciences · 2004 · 10.1016/j.lfs.2004.03.007

  • Spondyloenchondromatosis with D-2-hydroxyglutaric aciduria: a report of a second patient with this unusual combination

    Clinical Dysmorphology · 2003 · 10.1097/00019605-200304000-00004

  • Sublethal effects of copper on the freshwater crab Potamonautes warreni

    Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · 2002 · 10.1016/s1095-6433(02)00214-3

  • Variable clinical presentation in three patients with 3‐methylglutaconyl‐coenzyme A hydratase deficiency

    Journal of Inherited Metabolic Disease · 1998 · 10.1023/a:1005476315892

  • Non-catalytic oxidation of water-slurried coal with oxygen: identification of fulvic acids and acute toxicity

    Fuel · 1997 · 10.1016/s0016-2361(96)00194-9

  • Prenatal analysis in two suspected cases of glutathione synthetase deficiency

    Journal of Inherited Metabolic Disease · 1992 · 10.1007/bf00714275

Current projects

    No projects listed.