Thumbi Ndung’u
Researcher Next ID · RN-043130
Researcher · Immunology and Microbiology
Ragon Institute of MGH, MIT and Harvard
Cambridge, South Africa
- Works count
- 515
- Citation count
- 18,418
- H-index
- 71
- i10-index
- 267
Research interests
Publications
SARS-CoV-2 prolonged infection during advanced HIV disease evolves extensive immune escape
Cell Host & Microbe · 2022 · https://doi.org/10.1016/j.chom.2022.01.005
Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization
Nature · 2021 · https://doi.org/10.1038/s41586-021-04387-1
Research priorities for an HIV cure: International AIDS Society Global Scientific Strategy 2021
Nature Medicine · 2021 · https://doi.org/10.1038/s41591-021-01590-5
Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis
Nature · 2019 · https://doi.org/10.1038/s41586-019-1276-2
Elevated HLA-A expression impairs HIV control through inhibition of NKG2A-expressing cells
Science · 2018 · https://doi.org/10.1126/science.aam8825
Clonal expansion of genome-intact HIV-1 in functionally polarized Th1 CD4+ T cells
Journal of Clinical Investigation · 2017 · https://doi.org/10.1172/jci93289
Lactobacillus-Deficient Cervicovaginal Bacterial Communities Are Associated with Increased HIV Acquisition in Young South African Women
Immunity · 2017 · https://doi.org/10.1016/j.immuni.2016.12.013
Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-1 Infection in the Absence of Viral Suppression
Immunity · 2016 · https://doi.org/10.1016/j.immuni.2016.01.006
Comprehensive serological profiling of human populations using a synthetic human virome
Science · 2015 · https://doi.org/10.1126/science.aaa0698
Cervicovaginal Bacteria Are a Major Modulator of Host Inflammatory Responses in the Female Genital Tract
Immunity · 2015 · https://doi.org/10.1016/j.immuni.2015.04.019
Magnitude and Kinetics of CD8+ T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point
Immunity · 2015 · https://doi.org/10.1016/j.immuni.2015.08.012
Selection bias at the heterosexual HIV-1 transmission bottleneck
Science · 2014 · https://doi.org/10.1126/science.1254031
Translating HIV Sequences into Quantitative Fitness Landscapes Predicts Viral Vulnerabilities for Rational Immunogen Design
Immunity · 2013 · https://doi.org/10.1016/j.immuni.2012.11.022
Additive Contribution of HLA Class I Alleles in the Immune Control of HIV-1 Infection
Journal of Virology · 2010 · https://doi.org/10.1128/jvi.00320-10
Adaptation of HIV-1 to human leukocyte antigen class I
Nature · 2009 · https://doi.org/10.1038/nature07746
Evolution of HLA-B*5703 HIV-1 escape mutations in HLA-B*5703–positive individuals and their transmission recipients
The Journal of Experimental Medicine · 2009 · https://doi.org/10.1084/jem.20081984
HLA Class I-Driven Evolution of Human Immunodeficiency Virus Type 1 Subtype C Proteome: Immune Escape and Viral Load
Journal of Virology · 2008 · https://doi.org/10.1128/jvi.02455-07
Central Role of Reverting Mutations in HLA Associations with Human Immunodeficiency Virus Set Point
Journal of Virology · 2008 · https://doi.org/10.1128/jvi.00580-08
Current projects
No projects listed.