Lothar Lilge

Research interests

Publications

• Transition Metal Complexes and Photodynamic Therapy from a Tumor-Centered Approach: Challenges, Opportunities, and Highlights from the Development of TLD1433

  Chemical Reviews · 2018 · https://doi.org/10.1021/acs.chemrev.8b00211

• A ruthenium(ii) based photosensitizer and transferrin complexes enhance photo-physical properties, cell uptake, and photodynamic therapy safety and efficacy

  Photochemical & Photobiological Sciences · 2016 · https://doi.org/10.1039/c5pp00450k

• A novel class of ruthenium-based photosensitizers effectively kills in vitro cancer cells and in vivo tumors

  Photochemical & Photobiological Sciences · 2015 · https://doi.org/10.1039/c4pp00438h

• Antimicrobial photodynamic therapy with fulleropyrrolidine: photoinactivation mechanism of Staphylococcus aureus, in vitro and in vivo studies

  Applied Microbiology and Biotechnology · 2015 · https://doi.org/10.1007/s00253-015-6539-8

• Ru(II) dyads derived from α-oligothiophenes: A new class of potent and versatile photosensitizers for PDT

  Coordination Chemistry Reviews · 2014 · https://doi.org/10.1016/j.ccr.2014.04.012

• Differential expression of sirtuin family members in the developing, adult, and aged rat brain

  Frontiers in Aging Neuroscience · 2014 · 10.3389/fnagi.2014.00333

• Photodynamic inactivation of Staphylococcus aureus and methicillin-resistant Staphylococcus aureus with Ru(II)-based type I/type II photosensitizers

  Photodiagnosis and Photodynamic Therapy · 2013 · https://doi.org/10.1016/j.pdpdt.2013.07.001

• Drug delivery to the brain by focused ultrasound induced blood–brain barrier disruption: Quantitative evaluation of enhanced permeability of cerebral vasculature using two-photon microscopy

  Journal of Controlled Release · 2013 · https://doi.org/10.1016/j.jconrel.2013.08.029

• Next-generation acceleration and code optimization for light transport in turbid media using GPUs

  Biomedical Optics Express · 2010 · https://doi.org/10.1364/boe.1.000658

• Evidence for the Direct Binding of Phosphorylated p53 to Sites of DNA Breaks In vivo

  Cancer Research · 2005 · https://doi.org/10.1158/0008-5472.can-05-0729

• The Distribution of the Anticancer Drug Doxorubicin in Relation to Blood Vessels in Solid Tumors

  Clinical Cancer Research · 2005 · https://doi.org/10.1158/1078-0432.ccr-05-1664

• Metronomic Photodynamic Therapy as a New Paradigm for Photodynamic Therapy: Rationale and Preclinical Evaluation of Technical Feasibility for Treating Malignant Brain Tumors¶

  Photochemistry and Photobiology · 2004 · https://doi.org/10.1562/2004-03-05-ra-100.1

• Microfabricated System for Parallel Single-Cell Capillary Electrophoresis

  Analytical Chemistry · 2004 · https://doi.org/10.1021/ac0496906

• Effects of 630-, 660-, 810-, and 905-nm Laser Irradiation Delivering Radiant Exposure of 1-50 J/cm 2 on Three Species of Bacteria in Vitro

  Journal of Clinical Laser Medicine & Surgery · 2002 · https://doi.org/10.1089/104454702320901116

• Apoptosis induced in vivo by photodynamic therapy in normal brain and intracranial tumour tissue

  British Journal of Cancer · 2000 · 10.1054/bjoc.2000.1426

• Photodynamic Therapy of Intracranial Tissues: A Preclinical Comparative Study of Four Different Photosensitizers

  Journal of Clinical Laser Medicine & Surgery · 1998 · https://doi.org/10.1089/clm.1998.16.81

• Implicit and explicit dosimetry in photodynamic therapy: a New paradigm

  Lasers in Medical Science · 1997 · https://doi.org/10.1007/bf02765099

• Why do veins appear blue? A new look at an old question

  Applied Optics · 1996 · 10.1364/ao.35.001151

• Spatially resolved absolute diffuse reflectance measurements for noninvasive determination of the optical scattering and absorption coefficients of biological tissue

  Applied Optics · 1996 · https://doi.org/10.1364/ao.35.002304

Current projects

No projects listed.