Jun‐ichi Tamura

Research interests

Publications

• Glycan sulfation patterns define autophagy flux at axon tip via PTPRσ-cortactin axis

  Nature Chemical Biology · 2019 · 10.1038/s41589-019-0274-x

• Chondroitin sulfate-E fine-tunes osteoblast differentiation via ERK1/2, Smad3 and Smad1/5/8 signaling by binding to N-cadherin and cadherin-11

  Biochemical and Biophysical Research Communications · 2012 · 10.1016/j.bbrc.2012.03.024

• FAM20B is a kinase that phosphorylates xylose in the glycosaminoglycan–protein linkage region

  Biochemical Journal · 2009 · https://doi.org/10.1042/bj20090474

• 2-O-Phosphorylation of Xylose and 6-O-Sulfation of Galactose in the Protein Linkage Region of Glycosaminoglycans Influence the Glucuronyltransferase-I Activity Involved in the Linkage Region Synthesis

  Journal of Biological Chemistry · 2008 · 10.1074/jbc.m709556200

• Identification of Chondroitin Sulfate Glucuronyltransferase as Chondroitin Synthase-3 Involved in Chondroitin Polymerization

  Journal of Biological Chemistry · 2008 · https://doi.org/10.1074/jbc.m707549200

• Synthesis of chondroitin sulfate E octasaccharide in a repeating region involving an acetamide auxiliary

  Carbohydrate Research · 2007 · 10.1016/j.carres.2007.09.009

• Mitochondrial reactive oxygen species and c-Src play a critical role in hypoxic response in vascular smooth muscle cells

  Cardiovascular Research · 2005 · 10.1016/j.cardiores.2005.04.017

• Vascular Endothelial Growth Factor is an Autocrine Growth Factor for Cardiac Myxoma Cells

  Circulation Journal · 2004 · 10.1253/circj.68.488

• In Vitro Heparan Sulfate Polymerization

  Journal of Biological Chemistry · 2003 · 10.1074/jbc.m304831200

• A case-control study of purple urine bag syndrome in geriatric wards

  Journal of Infection and Chemotherapy · 2003 · 10.1007/s10156-002-0210-x

• Molecular Cloning and Expression of a Second Chondroitin N-Acetylgalactosaminyltransferase Involved in the Initiation and Elongation of Chondroitin/Dermatan Sulfate

  Journal of Biological Chemistry · 2003 · 10.1074/jbc.m209446200

• Molecular Cloning and Expression of Human ChondroitinN-Acetylgalactosaminyltransferase

  Journal of Biological Chemistry · 2002 · 10.1074/jbc.m111434200

• Zn DEFICIENCY AGGRAVATES HYPERTENSION IN SPONTANEOUSLY HYPERTENSIVE RATS: POSSIBLE ROLE OF Cu/Zn-SUPEROXIDE DISMUTASE

  Clinical and Experimental Hypertension · 2002 · 10.1081/ceh-120004797

• Inflammatory cytokines in vitreous fluid and serum of patients with diabetic vitreoretinopathy

  Journal of Diabetes and its Complications · 2001 · 10.1016/s1056-8727(01)00155-6

• Human tumor suppressor EXT gene family members EXTL1 and EXTL3 encode α1,4- N -acetylglucosaminyltransferases that likely are involved in heparan sulfate/ heparin biosynthesis

  Proceedings of the National Academy of Sciences · 2001 · https://doi.org/10.1073/pnas.131188498

• rib-2, a Caenorhabditis elegans Homolog of the Human Tumor Suppressor EXT Genes Encodes a Novel α1,4-N-Acetylglucosaminyltransferase Involved in the Biosynthetic Initiation and Elongation of Heparan Sulfate

  Journal of Biological Chemistry · 2001 · 10.1074/jbc.c000835200

• Immunomodulation by vitamin B12: augmentation of CD8+ T lymphocytes and natural killer (NK) cell activity in vitamin B12-deficient patients by methyl-B12 treatment

  Clinical & Experimental Immunology · 1999 · 10.1046/j.1365-2249.1999.00870.x

• Molecular Cloning and Expression of Glucuronyltransferase I Involved in the Biosynthesis of the Glycosaminoglycan-Protein Linkage Region of Proteoglycans

  Journal of Biological Chemistry · 1998 · https://doi.org/10.1074/jbc.273.12.6615

• Analysis of prognostic factors in newly diagnosed acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy. Japan Adult Leukemia Study Group.

  Journal of Clinical Oncology · 1998 · https://doi.org/10.1200/jco.1998.16.1.78

• Treatment of refractory cases of atopic dermatitis with acidic hot-spring bathing.

  Acta Dermato Venereologica · 1997 · 10.2340/0001555577452454

• Regulation of chondroitin sulfate biosynthesis by specific sulfation: acceptor specificity of serum β-GalNAc transferase revealed by structurally defined oligosaccharides

  Glycobiology · 1997 · 10.1093/glycob/7.4.531

• Internal tandem duplication of FLT3 associated with leukocytosis in acute promyelocytic leukemia

  Leukemia · 1997 · https://doi.org/10.1038/sj.leu.2400756

• FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

  Nature · 1992 · https://doi.org/10.1038/357692a0

• Cloning and characterization of molecular isoforms of the catalytic subunit of calcineurin using nonisotopic methods.

  Journal of Biological Chemistry · 1990 · 10.1016/s0021-9258(19)38593-x

• Is the circadian change in hematocrit and blood viscosity a factor triggering cerebral and myocardial infarction?

  Stroke · 1987 · 10.1161/str.18.4.812b

Current projects

No projects listed.