Mark A. Sussman

Research interests

Publications

• BNIP3L/NIX and FUNDC1-mediated mitophagy is required for mitochondrial network remodeling during cardiac progenitor cell differentiation

  Autophagy · 2019 · 10.1080/15548627.2019.1580095

• Mechanisms of Cardiac Repair and Regeneration

  Circulation Research · 2018 · 10.1161/circresaha.117.312586

• Global position paper on cardiovascular regenerative medicine

  European Heart Journal · 2017 · 10.1093/eurheartj/ehx248

• Cardiomyocyte Regeneration

  Circulation · 2017 · https://doi.org/10.1161/circulationaha.117.029343

• Cardiomyocyte Regeneration: A Consensus Statement.

  PubMed · 2017 · https://doi.org/10.1161/circulationaha.117.029343

• Loss of MCL-1 leads to impaired autophagy and rapid development of heart failure

  Genes & Development · 2013 · 10.1101/gad.215871.113

• Enhanced Effect of Combining Human Cardiac Stem Cells and Bone Marrow Mesenchymal Stem Cells to Reduce Infarct Size and to Restore Cardiac Function After Myocardial Infarction

  Circulation · 2012 · 10.1161/circulationaha.112.131110

• Animal Models of Heart Failure

  Circulation Research · 2012 · https://doi.org/10.1161/res.0b013e3182582523

• Signal Transducers and Activators of Transcription-3/Pim1 Axis Plays a Critical Role in the Pathogenesis of Human Pulmonary Arterial Hypertension

  Circulation · 2011 · 10.1161/circulationaha.110.963314

• Myocardial AKT: The Omnipresent Nexus

  Physiological Reviews · 2011 · 10.1152/physrev.00024.2010

• Juvenile Exposure to Anthracyclines Impairs Cardiac Progenitor Cell Function and Vascularization Resulting in Greater Susceptibility to Stress-Induced Myocardial Injury in Adult Mice

  Circulation · 2010 · 10.1161/circulationaha.109.902221

• Enhancement of Myocardial Regeneration Through Genetic Engineering of Cardiac Progenitor Cells Expressing Pim-1 Kinase

  Circulation · 2009 · 10.1161/circulationaha.109.884403

• Activation of Notch-Mediated Protective Signaling in the Myocardium

  Circulation Research · 2008 · 10.1161/circresaha.107.164749

• Mesencephalic Astrocyte-Derived Neurotrophic Factor Is an Ischemia-Inducible Secreted Endoplasmic Reticulum Stress Response Protein in the Heart

  Circulation Research · 2008 · 10.1161/circresaha.108.180679

• Bone marrow cells adopt the cardiomyogenic fate in vivo

  Proceedings of the National Academy of Sciences · 2007 · 10.1073/pnas.0706406104

• Pim-1 regulates cardiomyocyte survival downstream of Akt

  Nature Medicine · 2007 · 10.1038/nm1671

• Endoplasmic Reticulum Stress Gene Induction and Protection From Ischemia/Reperfusion Injury in the Hearts of Transgenic Mice With a Tamoxifen-Regulated Form of ATF6

  Circulation Research · 2006 · 10.1161/01.res.0000220643.65941.8d

• Activation of the Unfolded Protein Response in Infarcted Mouse Heart and Hypoxic Cultured Cardiac Myocytes

  Circulation Research · 2006 · 10.1161/01.res.0000233317.70421.03

• The Rac and Rho Hall of Fame

  Circulation Research · 2006 · 10.1161/01.res.0000216039.75913.9e

• Cardiac Stem Cell and Myocyte Aging, Heart Failure, and Insulin-Like Growth Factor-1 Overexpression

  Circulation Research · 2004 · https://doi.org/10.1161/01.res.0000117306.10142.50

• Alterations at the Intercalated Disk Associated with the Absence of Muscle Lim Protein

  The Journal of Cell Biology · 2001 · 10.1083/jcb.153.4.763

• Myocardial Akt Activation and Gender

  Circulation Research · 2001 · 10.1161/hh1001.090858

• Altered focal adhesion regulation correlates with cardiomyopathy in mice expressing constitutively active rac1

  Journal of Clinical Investigation · 2000 · 10.1172/jci8497

• Decreased SLIM1 Expression and Increased Gelsolin Expression in Failing Human Hearts Measured by High-Density Oligonucleotide Arrays

  Circulation · 2000 · 10.1161/01.cir.102.25.3046

• Prevention of Cardiac Hypertrophy in Mice by Calcineurin Inhibition

  Science · 1998 · https://doi.org/10.1126/science.281.5383.1690

Current projects

No projects listed.