Claudia Lanari

Research interests

Publications

• Beneficial Effects of Mifepristone Treatment in Patients with Breast Cancer Selected by the Progesterone Receptor Isoform Ratio: Results from the MIPRA Trial

  Clinical Cancer Research · 2022 · 10.1158/1078-0432.ccr-22-2060

• Enhanced Antitumor Immunity via Endocrine Therapy Prevents Mammary Tumor Relapse and Increases Immune Checkpoint Blockade Sensitivity

  Cancer Research · 2020 · 10.1158/0008-5472.can-20-1441

• FGF2 induces breast cancer growth through ligand‐independent activation and recruitment of ERα and PRBΔ4 isoform to MYC regulatory sequences

  International Journal of Cancer · 2019 · 10.1002/ijc.32252

• Hormone receptors in breast cancer: more than estrogen receptors.

  PubMed · 2019

• AKT1 and AKT2 isoforms play distinct roles during breast cancer progression through the regulation of specific downstream proteins

  Scientific Reports · 2017 · 10.1038/srep44244

• Progesterone Receptor Isoform Ratio: A Breast Cancer Prognostic and Predictive Factor for Antiprogestin Responsiveness

  JNCI Journal of the National Cancer Institute · 2016 · 10.1093/jnci/djw317

• Progestin and antiprogestin responsiveness in breast cancer is driven by the PRA / PRB ratio via AIB 1 or SMRT recruitment to the CCND 1 and MYC promoters

  International Journal of Cancer · 2014 · 10.1002/ijc.29304

• Action of hexachlorobenzene on tumor growth and metastasis in different experimental models

  Toxicology and Applied Pharmacology · 2013 · 10.1016/j.taap.2013.02.007

• Estrogen Receptor Alpha Mediates Progestin-Induced Mammary Tumor Growth by Interacting with Progesterone Receptors at the Cyclin D1/MYC Promoters

  Cancer Research · 2012 · 10.1158/0008-5472.can-11-3290

• Estrogen receptor beta growth-inhibitory effects are repressed through activation of MAPK and PI3K signalling in mammary epithelial and breast cancer cells

  Oncogene · 2012 · 10.1038/onc.2012.261

• Antiprogestins in breast cancer treatment: are we ready?

  Endocrine Related Cancer · 2012 · 10.1530/erc-11-0378

• PI3K/AKT pathway regulates phosphorylation of steroid receptors, hormone independence and tumor differentiation in breast cancer

  Carcinogenesis · 2011 · 10.1093/carcin/bgr303

• α2-Adrenoceptors Enhance Cell Proliferation and Mammary Tumor Growth Acting Through both the Stroma and the Tumor Cells

  Current Cancer Drug Targets · 2011 · 10.2174/156800911796191051

• Interaction between FGFR-2, STAT5, and Progesterone Receptors in Breast Cancer

  Cancer Research · 2011 · 10.1158/0008-5472.can-10-3074

• The MPA mouse breast cancer model: evidence for a role of progesterone receptors in breast cancer

  Endocrine Related Cancer · 2009 · 10.1677/erc-08-0244

• NK Cells Expressing a Progesterone Receptor Are Susceptible to Progesterone-Induced Apoptosis

  The Journal of Immunology · 2008 · 10.4049/jimmunol.180.8.5746

• Carcinoma‐associated fibroblasts activate progesterone receptors and induce hormone independent mammary tumor growth: A role for the FGF‐2/FGFR‐2 axis

  International Journal of Cancer · 2008 · 10.1002/ijc.23802

• α2‐Adrenoceptor action on cell proliferation and mammary tumour growth in mice

  British Journal of Pharmacology · 2008 · 10.1038/bjp.2008.278

• Progesterone receptors - animal models and cell signaling in breast cancer Diverse activation pathways for the progesterone receptor - possible implications for breast biology and cancer

  Breast Cancer Research · 2002 · 10.1186/bcr539

• Five novel hormone-responsive cell lines derived from murine mammary ductal carcinomas: in vivo and in vitro effects of estrogens and progestins.

  PubMed · 2001

• Effect of medroxyprogesterone acetate (MPA) and serum factors on cell proliferation in primary cultures of an MPA-induced mammary adenocarcinoma

  Breast Cancer Research and Treatment · 1995 · 10.1007/bf00668207

• Hormone dependence of a mouse mammary tumor line inducedin vivo by medroxyprogesterone acetate

  Breast Cancer Research and Treatment · 1990 · 10.1007/bf01812682

• Mammary adenocarcinomas induced by medroxyprogesterone acetate: Hormone dependence and egf receptors of BALB/c In vivo sublines

  International Journal of Cancer · 1989 · 10.1002/ijc.2910430518

• Mouse mammary tumors induced by medroxyprogesterone acetate: immunohistochemistry and hormonal receptors.

  PubMed · 1987

• Induction of mammary adenocarcinomas by medroxyprogesterone acetate in BALBc female mice

  Cancer Letters · 1986 · 10.1016/0304-3835(86)90027-3

Current projects

No projects listed.