Laura Iris Cosen-Binker

Research interests

Publications

• Palmitic acid increases invasiveness of pancreatic cancer cells AsPC-1 through TLR4/ROS/NF-κB/MMP-9 signaling pathway

  Biochemical and Biophysical Research Communications · 2017 · 10.1016/j.bbrc.2017.01.051

• Ex vivo human pancreatic slice preparations offer a valuable model for studying pancreatic exocrine biology

  Journal of Biological Chemistry · 2017 · 10.1074/jbc.m117.777433

• TGF-β1 increases invasiveness of SW1990 cells through Rac1/ROS/NF-κB/IL-6/MMP-2

  Biochemical and Biophysical Research Communications · 2011 · 10.1016/j.bbrc.2011.01.023

• Hypoxia–reoxygenation increase invasiveness of PANC-1 cells through Rac1/MMP-2

  Biochemical and Biophysical Research Communications · 2010 · 10.1016/j.bbrc.2010.01.125

• Facioscapulohumeral Disease

  Journal · 2009 · 10.1007/978-3-540-29676-8_8486

• Functional Constipation

  Journal · 2009 · 10.1007/978-3-540-29676-8_8212

• LPS-stimulated MUC5AC production involves Rac1-dependent MMP-9 secretion and activation in NCI-H292 cells

  Biochemical and Biophysical Research Communications · 2009 · 10.1016/j.bbrc.2009.05.136

• EGF promotes invasion by PANC-1 cells through Rac1/ROS-dependent secretion and activation of MMP-2

  Biochemical and Biophysical Research Communications · 2008 · 10.1016/j.bbrc.2008.12.080

• Inhibition of Rac1 decreases the severity of pancreatitis and pancreatitis‐associated lung injury in mice

  Experimental Physiology · 2008 · 10.1113/expphysiol.2008.043141

• VAMP8 is the v-SNARE that mediates basolateral exocytosis in a mouse model of alcoholic pancreatitis

  Journal of Clinical Investigation · 2008 · 10.1172/jci34672

• Further Studies in Deoxycorticosterone Acetate Treated Rats: Brain Content of Mineralocorticoid and Glucocorticoid Receptors and Effect of Steroid Antagonists on Salt Intake

  Neuroendocrinology · 2008 · 10.1159/000126832

• Recent insights into the cellular mechanisms of acute pancreatitis

  Canadian Journal of Gastroenterology · 2007 · 10.1155/2007/930424

• Alcohol/Cholecystokinin-evoked Pancreatic Acinar Basolateral Exocytosis Is Mediated by Protein Kinase Cα Phosphorylation of Munc18c

  Journal of Biological Chemistry · 2007 · 10.1074/jbc.m611132200

• Arrested maturation ofNeisseria-containing phagosomes in the absence of the lysosome-associated membrane proteins, LAMP-1 and LAMP-2

  Cellular Microbiology · 2007 · 10.1111/j.1462-5822.2007.00946.x

• Alcohol-Induced Protein Kinase Cα Phosphorylation of Munc18c in Carbachol-Stimulated Acini Causes Basolateral Exocytosis

  Gastroenterology · 2007 · 10.1053/j.gastro.2007.01.042

• A Cytosolic Splice Variant of Cab45 Interacts with Munc18b and Impacts on Amylase Secretion by Pancreatic Acini

  Molecular Biology of the Cell · 2007 · 10.1091/mbc.e06-10-0950

• Relaxin prevents the development of severe acute pancreatitis

  World Journal of Gastroenterology · 2006 · 10.3748/wjg.v12.i10.1558

• Cortactin: The Gray Eminence of the Cytoskeleton

  Physiology · 2006 · 10.1152/physiol.00012.2006

• Influence of stress in acute pancreatitis and correlation with stress-induced gastric ulcer

  Pancreatology · 2004 · 10.1159/000079956

• Experimental Model of Acute Pancreatitis in Wistar Rat: Glucocorticoid Treatment Profile

  Digestive Diseases and Sciences · 2003 · 10.1023/a:1024791101859

Current projects

No projects listed.