Patricia A.M. Williams

Research interests

Publications

• Ternary copper(II) complex of 5-hydroxytryptophan and 1,10-phenanthroline with several pharmacological properties and an adequate safety profile

  Journal of Inorganic Biochemistry · 2019 · 10.1016/j.jinorgbio.2019.110933

• Azilsartan and its Zn(II) complex. Synthesis, anticancer mechanisms of action and binding to bovine serum albumin

  Toxicology in Vitro · 2018 · 10.1016/j.tiv.2018.01.009

• Antioxidant and anticancer effects and bioavailability studies of the flavonoid baicalin and its oxidovanadium(IV) complex

  Journal of Inorganic Biochemistry · 2016 · 10.1016/j.jinorgbio.2016.11.005

• Bovine serum albumin binding, antioxidant and anticancer properties of an oxidovanadium(IV) complex with luteolin

  Journal of Inorganic Biochemistry · 2016 · 10.1016/j.jinorgbio.2016.01.021

• Antioxidant, anticancer activities and mechanistic studies of the flavone glycoside diosmin and its oxidovanadium(IV) complex. Interactions with bovine serum albumin

  Bioorganic & Medicinal Chemistry · 2016 · 10.1016/j.bmc.2016.06.053

• Insights into the mechanisms underlying the antitumor activity of an oxidovanadium(IV) compound with the antioxidant naringenin. Albumin binding studies

  Journal of Inorganic Biochemistry · 2015 · 10.1016/j.jinorgbio.2015.04.011

• Antitumoral, Antihypertensive, Antimicrobial, and Antioxidant Effects of an Octanuclear Copper(II)-Telmisartan Complex with an Hydrophobic Nanometer Hole

  Inorganic Chemistry · 2014 · 10.1021/ic500483p

• Promising antioxidant and anticancer (human breast cancer) oxidovanadium(IV) complex of chlorogenic acid. Synthesis, characterization and spectroscopic examination on the transport mechanism with bovine serum albumin

  Journal of Inorganic Biochemistry · 2014 · 10.1016/j.jinorgbio.2014.02.013

• Antitumor properties of a vanadyl(iv) complex with the flavonoid chrysin [VO(chrysin)2EtOH]2 in a human osteosarcoma model: the role of oxidative stress and apoptosis

  Dalton Transactions · 2013 · 10.1039/c3dt50524c

• Antiproliferative and apoptosis-inducing activity of an oxidovanadium(IV) complex with the flavonoid silibinin against osteosarcoma cells

  JBIC Journal of Biological Inorganic Chemistry · 2013 · 10.1007/s00775-013-1061-x

• Biological evaluation of morin and its new oxovanadium(IV) complex as antio-xidant and specific anti-cancer agents

  Chemico-Biological Interactions · 2013 · 10.1016/j.cbi.2013.10.006

• Antioxidant, DNA cleavage, and cellular effects of silibinin and a new oxovanadium(IV)/silibinin complex

  JBIC Journal of Biological Inorganic Chemistry · 2011 · 10.1007/s00775-011-0769-8

• Role of oxidative stress in the antitumoral action of a new vanadyl(IV) complex with the flavonoid chrysin in two osteoblast cell lines: relationship with the radical scavenger activity

  JBIC Journal of Biological Inorganic Chemistry · 2010 · 10.1007/s00775-010-0652-z

• Antioxidant effects of the VO(IV) hesperidin complex and its role in cancer chemoprevention

  JBIC Journal of Biological Inorganic Chemistry · 2007 · 10.1007/s00775-007-0332-9

• Synthesis, characterization, antitumoral and osteogenic activities of quercetin vanadyl(IV) complexes

  JBIC Journal of Biological Inorganic Chemistry · 2006 · 10.1007/s00775-006-0122-9

• Synthesis, structure and antifungal properties of Co(II)–sulfathiazolate complexes

  Polyhedron · 2005 · 10.1016/j.poly.2004.12.017

• Synthesis of a new vanadyl(IV) complex with trehalose (TreVO): insulin-mimetic activities in osteoblast-like cells in culture

  JBIC Journal of Biological Inorganic Chemistry · 2003 · 10.1007/s00775-002-0438-z

• Three new vanadyl(IV) complexes with non-steroidal anti-inflammatory drugs (Ibuprofen, Naproxen and Tolmetin). Bioactivity on osteoblast-like cells in culture

  Journal of Inorganic Biochemistry · 2002 · 10.1016/s0162-0134(01)00368-3

• Activation of the NPY Y5 receptor regulates both feeding and energy expenditure

  American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 1999 · 10.1152/ajpregu.1999.277.5.r1428

• Differential Effects of Intracerebroventricular Glucagon-Like Peptide-1 on Feeding and Energy Expenditure Regulation

  Peptides · 1998 · 10.1016/s0196-9781(98)00033-3

• Synthesis and characterization of oxovanadium(IV) complexes with saccharides

  Carbohydrate Research · 1997 · 10.1016/s0008-6215(97)00132-8

• Evidence for the Presence of a Proteinase-Activated Receptor Distinct From the Thrombin Receptor in Vascular Endothelial Cells

  Circulation Research · 1996 · 10.1161/01.res.78.4.581

• A novel DNA lesion in neoplastic livers of feral fish: 2,6-diamino-4-hydroxy-5-formamidopyrimidine

  Carcinogenesis · 1990 · 10.1093/carcin/11.6.1045

Current projects

No projects listed.